Zobrazeno 1 - 10
of 164
pro vyhledávání: '"F. S. Lee"'
Autor:
Ronald F. S. Lee, Alexey Chernobrovkin, Dorothea Rutishauser, Claire S. Allardyce, David Hacker, Kai Johnsson, Roman A. Zubarev, Paul J. Dyson
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The emerging technique termed functional identification of target by expression proteomics (FITExP) has been shown to identify the key protein targets of anti-cancer drugs. Here, we use this approach to elucidate the proteins involved in the
Externí odkaz:
https://doaj.org/article/4de57fb3c86d42eab3c5f8158d0517a9
Autor:
Lin Kooi Ong, Ronald F. S. Lee, Beng Ti Tey, Iekhsan Othman, Wen Siang Tan, Ken Fong Chen, Syafiq Asnawi Zainal Abidin
Publikováno v:
Reviews in Aquaculture. 13:2117-2141
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf0f7d14512341b031d6aeca0419ec3c
https://doi.org/10.1111/raq.12562
https://doi.org/10.1111/raq.12562
Akademický článek
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Publikováno v:
Drying Technology. 40:1083-1102
Propolis, which is a bee glue is potentially a useful food additive since it contains antioxidant and preservative-like properties. However, its application in the food industry remains limited, du...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac1cd33c1f102ac06c6d4a1e5ca3d68f
https://doi.org/10.1080/07373937.2020.1850470
https://doi.org/10.1080/07373937.2020.1850470
Publikováno v:
Analytical Chemistry. 89:11985-11989
Metallodrug-protein interactions contribute to their therapeutic effect (even when DNA is the dominant target), side-effects and are implicit in drug resistance. Here, we provide mass spectrometric-based evidence to show that metallodrug interactions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f6248b87c71a2496850773f220de68
https://doi.org/10.1021/acs.analchem.7b02211
https://doi.org/10.1021/acs.analchem.7b02211
Autor:
Graham Knott, Anders Meibom, Tina Riedel, Kai Johnsson, Ronald F. S. Lee, Catherine Maclachlan, Paul J. Dyson, Curt A. Davey, Stéphane Escrig
Publikováno v:
Metallomics. 9:1413-1420
Cisplatin is a widely used anti-cancer drug, but its effect is often limited by acquired resistance to the compound during treatment. Here, we use a combination of transmission electron microscopy (TEM) and nanoscale-secondary ion mass spectrometry (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701bc905f19ea1042c87a2b3b2f244ea
https://doi.org/10.1039/c7mt00153c
https://doi.org/10.1039/c7mt00153c
Autor:
Roman A. Zubarev, Dorothea Rutishauser, Alexey Chernobrovkin, Kai Johnsson, David L. Hacker, Paul J. Dyson, Ronald F. S. Lee, Claire S. Allardyce
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
The emerging technique termed functional identification of target by expression proteomics (FITExP) has been shown to identify the key protein targets of anti-cancer drugs. Here, we use this approach to elucidate the proteins involved in the mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c246e6bae1fec0a1530df4813c07c131
https://doi.org/10.1038/s41598-017-01643-1
https://doi.org/10.1038/s41598-017-01643-1
Autor:
Laure Menin, Pornvichai Temboot, Ronald F. S. Lee, Luc Patiny, Paul J. Dyson, Adisorn Ratanaphan
Publikováno v:
Biochemical and biophysical research communications. 488(2)
RAPTA compounds, ([Ru(eta(6)-arene)(PTA)Cl-2], PTA = 1,3,5-triaza-7-phosphaadamantane), have been reported to overcome drug resistance in cisplatin resistant cells. However, the exact mechanism of these complexes is still largely unexplored. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bef00ec0b370a394aa1e477dff772cf
https://pubmed.ncbi.nlm.nih.gov/28501617
https://pubmed.ncbi.nlm.nih.gov/28501617
Autor:
Gunda Koellensperger, Bernhard K. Keppler, Paul J. Dyson, Ronald F. S. Lee, Sarah Theiner, Anders Meibom
Publikováno v:
Metallomics : integrated biometal science. 9(4)
Mass spectrometry imaging is being increasingly used in metal-based anticancer drug development to study elemental and/or molecular drug distributions in different biological systems. The main analytical tools employed are SIMS (especially nanoSIMS),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f52dbeeddc5ace273eb3a6460dd8b38
https://pubmed.ncbi.nlm.nih.gov/28154861
https://pubmed.ncbi.nlm.nih.gov/28154861
Publikováno v:
The journal of nutrition, health & aging. 16:660-665
Poor appetite is one of the main contributing factors of poor nutritional status among elderly individuals. Recognizing the importance of assessment of appetite, a cross sectional study was conducted to determine the validity of appetite screening to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cfd96a732de9bd1644ed0f287ad494d
https://doi.org/10.1007/s12603-012-0056-6
https://doi.org/10.1007/s12603-012-0056-6