Evidence for Constitutive Microbiota-Dependent Short-Term Control of Food Intake in Mice: Is There a Link with Inflammation, Oxidative Stress, Endotoxemia, and GLP-1?

Autor: Selma Ben Fradj, Emmanuelle Nédélec, Juliette Salvi, Mélanie Fouesnard, Marine Huillet, Gaëtan Pallot, Céline Cansell, Clara Sanchez, Catherine Philippe, Vincent Gigot, Aleth Lemoine, Doriane Trompier, Thomas Henry, Virginie Petrilli, Benedicte F. Py, Hervé Guillou, Nicolas Loiseau, Sandrine Ellero-Simatos, Jean-Louis Nahon, Carole Rovère, Jacques Grober, Gaelle Boudry, Véronique Douard, Alexandre Benani

Publikováno v: Antioxidants and Redox Signaling
Antioxidants and Redox Signaling, 2022, 37 (4-6), pp.349-369. ⟨10.1089/ars.2021.0095⟩

International audience; AIMS: Although prebiotics, probiotics, and fecal transplantation can alter the sensation of hunger and/or feeding behavior, the role of the constitutive gut microbiota in the short-term regulation of food intake during normal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::858f4a298e1bf0e846e2bdb61536f668
https://doi.org/10.1089/ars.2021.0095

L’inflammasome NLRP3 dans la physiopathologie des infections virales

Autor: Marlène Chemarin, Océane Dufies, Anastassia Mazet, Eva Mellan, Rémy Coudereau, Bénédicte F. Py, Laurent Boyer, Fabienne Venet

Publikováno v: médecine/sciences. 38:545-552

L’inflammasome NLRP3 est un complexe multiprotéique intracellulaire impliqué dans la réponse immunitaire innée. Après la détection de signaux de dangers, tels que ceux provenant d’agents pathogènes, ce complexe s’assemble afin d’initie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::39682a86e19b026967b6558d51c90db8
https://doi.org/10.1051/medsci/2022080

Caspase-11 Controls Interleukin-1β Release through Degradation of TRPC1

Autor: Bénédicte F. Py, Mingzhi Jin, Bimal N. Desai, Anirudh Penumaka, Hong Zhu, Maike Kober, Alexander Dietrich, Marta M. Lipinski, Thomas Henry, David E. Clapham, Junying Yuan

Publikováno v: Cell Reports, Vol 6, Iss 6, Pp 1122-1128 (2014)

Caspase-11 is a highly inducible caspase that controls both inflammatory responses and cell death. Caspase-11 controls interleukin 1β (IL-1β) secretion by potentiating caspase-1 activation and induces caspase-1-independent pyroptosis downstream of

Externí odkaz: https://doaj.org/article/b44a020f82154fb5b96661a67e2a8b58

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Escherichia coli Rho GTPase-activating toxin CNF1 mediates NLRP3 inflammasome activation via p21-activated kinases-1/2 during bacteraemia in mice

Autor: Alexandre Gallerand, Arnaud Jacquel, Pedro Henrique Viana Saavedra, Cedric Torre, Paul Chaintreuil, Sandrine Marchetti, Alissa Majoor, Mohamed Lamkanfi, Raymond Ruimy, Céline Loubatier, Amaury Rey, Anne Doye, Laurent Boyer, Benedicte F. Py, Grégory Michel, Johan Courjon, Rodolphe Guinamard, Patrick Munro, Dorota Czerucka, Orane Visvikis, Océane Dufies, Els Verhoeyen

Publikováno v: Nature Microbiology
Nature Microbiology, Nature Publishing Group, 2021, 6 (3), pp.401-412. ⟨10.1038/s41564-020-00832-5⟩
Nature microbiology
Nature Microbiology, 2021, 6 (3), pp.401-412. ⟨10.1038/s41564-020-00832-5⟩

Inflammasomes are signalling platforms that are assembled in response to infection or sterile inflammation by cytosolic pattern recognition receptors. The consequent inflammasome-triggered caspase-1 activation is critical for the host defence against

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f03b7b7351ee08b0a26e57e7c5e8244
https://hal.archives-ouvertes.fr/hal-03473187