Zobrazeno 1 - 10
of 477
pro vyhledávání: '"F. Ponte"'
Publikováno v:
Artificial Intelligence in Geosciences; Dec2024, Vol. 5, p1-13, 13p
Autor:
Christian Brand, Ahmad Sadique, Jacob L. Houghton, Kishore Gangangari, Jose F. Ponte, Jason S. Lewis, Naga Vara Kishore Pillarsetty, Jason A. Konner, Thomas Reiner
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Background The folate receptor α (FRα)-targeting antibody-drug conjugate (ADC), IMGN853, shows great antitumor activity against FRα-expressing tumors in vivo, but patient selection and consequently therapy outcome are based on immunohisto
Externí odkaz:
https://doaj.org/article/48194ca7f8f946429f00bb484510caba
Autor:
Alessandro D. Santin, Peter E. Schwartz, Masoud Azodi, Gloria S. Huang, Dan-Arin Silasi, Elena Ratner, Babak Litkouhi, Serena Wong, Pei Hui, Natalia Buza, Jose F. Ponte, Ashley Morneault, Katherine Dugan, Ghanshyam Yadav, Chanhee Han, Luca Zammataro, Jacqueline Feinberg, Francesco Riccio, Anna Bianchi, Francesca Pettinella, Gulden Menderes, Tomomi Egawa-Takata, Stefania Bellone, Elena Bonazzoli, Gary Altwerger
Immunohistochemistry (IHC) showing expression of FRα endometrioid cancer cell blocks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a47bbbe8a69d698bc12b43acf09e5e3e
https://doi.org/10.1158/1535-7163.22504590.v1
https://doi.org/10.1158/1535-7163.22504590.v1
Autor:
Alessandro D. Santin, Peter E. Schwartz, Masoud Azodi, Gloria S. Huang, Dan-Arin Silasi, Elena Ratner, Babak Litkouhi, Serena Wong, Pei Hui, Natalia Buza, Jose F. Ponte, Ashley Morneault, Katherine Dugan, Ghanshyam Yadav, Chanhee Han, Luca Zammataro, Jacqueline Feinberg, Francesco Riccio, Anna Bianchi, Francesca Pettinella, Gulden Menderes, Tomomi Egawa-Takata, Stefania Bellone, Elena Bonazzoli, Gary Altwerger
Grade 3 endometrioid and uterine serous carcinomas (USC) account for the vast majority of endometrial cancer deaths. The purpose of this study was to determine folic acid receptor alpha (FRα) expression in these biologically aggressive (type II) end
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a81646ed0c38f7c706dc160a71539783
https://doi.org/10.1158/1535-7163.c.6537780.v1
https://doi.org/10.1158/1535-7163.c.6537780.v1
Autor:
Greg M. Thurber, Richard Gregory, Jan Pinkas, Ravi Chari, Thomas A. Keating, Michael L. Miller, Yulius Setiady, Bahar Matin, Neeraj Kohli, Christopher Espelin, Olga Ab, Rassol Laleau, Eshita Khera, Leanne Lanieri, Jose F. Ponte
Supplementary figures and data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::633ee436ae1eb2f1537f2ada328961b9
https://doi.org/10.1158/1535-7163.22521463
https://doi.org/10.1158/1535-7163.22521463
Autor:
Ravi V.J. Chari, Thomas A. Keating, Jan Pinkas, Olga Ab, Katharine C. Lai, Yelena Kovtun, Nicholas C. Yoder, Jose F. Ponte, Rajeeva Singh, Luke Harris, Dilrukshi Vitharana, Chen Bai, Katie E. Archer, Qifeng Qiu, Lauren Harvey, Erin K. Maloney, Surina Sikka, Leanne Lanieri, Emily E. Reid, Paulin Salomon, Alan Wilhelm, Manami Shizuka, Michael L. Miller
Tumor-selective delivery of cytotoxic agents in the form of antibody–drug conjugates (ADCs) is now a clinically validated approach for cancer treatment. In an attempt to improve the clinical success rate of ADCs, emphasis has been recently placed o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d1e99e32e1b6463933f4f9a2e6edc1f
https://doi.org/10.1158/1535-7163.c.6537900.v1
https://doi.org/10.1158/1535-7163.c.6537900.v1
Autor:
Alessandro D. Santin, Peter E. Schwartz, Masoud Azodi, Gloria S. Huang, Dan-Arin Silasi, Elena Ratner, Babak Litkouhi, Serena Wong, Pei Hui, Natalia Buza, Jose F. Ponte, Ashley Morneault, Katherine Dugan, Ghanshyam Yadav, Chanhee Han, Luca Zammataro, Jacqueline Feinberg, Francesco Riccio, Anna Bianchi, Francesca Pettinella, Gulden Menderes, Tomomi Egawa-Takata, Stefania Bellone, Elena Bonazzoli, Gary Altwerger
Determination by ICso of IMGN853 cytotoxicity compared to controls, ADC isotype and M9346A, in primary USC cell lines (ie, END(K) 149 and ARK19) with 2+ FRα expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53be3b3c29dfd1353c8c582dd60bb588
https://doi.org/10.1158/1535-7163.22504572
https://doi.org/10.1158/1535-7163.22504572
Autor:
Alessandro D. Santin, Peter E. Schwartz, Masoud Azodi, Gloria S. Huang, Dan-Arin Silasi, Elena Ratner, Babak Litkouhi, Serena Wong, Pei Hui, Natalia Buza, Jose F. Ponte, Ashley Morneault, Katherine Dugan, Ghanshyam Yadav, Chanhee Han, Luca Zammataro, Jacqueline Feinberg, Francesco Riccio, Anna Bianchi, Francesca Pettinella, Gulden Menderes, Tomomi Egawa-Takata, Stefania Bellone, Elena Bonazzoli, Gary Altwerger
Endometrioid cell lines with demographics, stage, histologic grade, primary site of tumor, Mean fluorescence intensity (MFI) and score for FRα (folic acid alpha receptor).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84041e0d44be22aecf17d287e5cd0946
https://doi.org/10.1158/1535-7163.22504569.v1
https://doi.org/10.1158/1535-7163.22504569.v1
Autor:
Ravi V.J. Chari, Thomas A. Keating, Jan Pinkas, Olga Ab, Katharine C. Lai, Yelena Kovtun, Nicholas C. Yoder, Jose F. Ponte, Rajeeva Singh, Luke Harris, Dilrukshi Vitharana, Chen Bai, Katie E. Archer, Qifeng Qiu, Lauren Harvey, Erin K. Maloney, Surina Sikka, Leanne Lanieri, Emily E. Reid, Paulin Salomon, Alan Wilhelm, Manami Shizuka, Michael L. Miller
Figure S1. Structural representations and scheme for preparation of IGN ADCs. Figure S2A. In vitro potency comparing ADCs of an IGN DNA cross-linker and DNA alkylator. Figure S2B. In vitro potency comparing ADCs of an IGN DNA cross-linker and DNA alk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f568423d203af13cedff0663cdc34a8
https://doi.org/10.1158/1535-7163.22504929.v1
https://doi.org/10.1158/1535-7163.22504929.v1
Autor:
Alessandro D. Santin, Peter E. Schwartz, Masoud Azodi, Gloria S. Huang, Dan-Arin Silasi, Elena Ratner, Babak Litkouhi, Serena Wong, Pei Hui, Natalia Buza, Jose F. Ponte, Ashley Morneault, Katherine Dugan, Ghanshyam Yadav, Chanhee Han, Luca Zammataro, Jacqueline Feinberg, Francesco Riccio, Anna Bianchi, Francesca Pettinella, Gulden Menderes, Tomomi Egawa-Takata, Stefania Bellone, Elena Bonazzoli, Gary Altwerger
Immunohistochemistry (IHC) showing expression of FRα uterine serous cancer (USC) cell blocks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f04ff34ea7724140d47131b6dc949bf
https://doi.org/10.1158/1535-7163.22504578.v1
https://doi.org/10.1158/1535-7163.22504578.v1