Zobrazeno 1 - 6
of 6
pro vyhledávání: '"F. Phil Brooks"'
Autor:
William C. Thomas, F. Phil Brooks, Audrey A. Burnim, John-Paul Bacik, JoAnne Stubbe, Jason T. Kaelber, James Z. Chen, Nozomi Ando
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Ribonucleotide reductase (RNR) catalyzes the conversion of ribonucleotides to deoxyribonucleotides, which is an essential step in DNA synthesis. Here the authors use small-angle X-ray scattering, X-ray crystallography, and cryo-electron microscopy to
Externí odkaz:
https://doaj.org/article/6430e8e15b544ccd941a8a5b5dbc7669
Publikováno v:
eLife, Vol 12 (2023)
Many channelrhodopsins are permeable to protons. We found that in neurons, activation of a high-current channelrhodopsin, CheRiff, led to significant acidification, with faster acidification in the dendrites than in the soma. Experiments with pattern
Externí odkaz:
https://doaj.org/article/b5dff882a0eb4000b1af069c8b910784
Autor:
Daan Brinks, F. Phil Brooks, Adam E. Cohen, Miao-Ping Chien, Benjamin Gmeiner, He Tian, Yoav Adam, Simon Kheifets, Guilherme Testa-Silva, William Bloxham
Publikováno v:
Science Advances, 7(19)
Science advances, 7(19):eabe3216. American Association for the Advancement of Science
Science Advances
Science advances, 7(19):eabe3216. American Association for the Advancement of Science
Science Advances
Photoactivated genetically encoded voltage indicators (GEVIs) have the potential to enable optically sectioned voltage imaging at the intersection of a photoactivation beam and an imaging beam. We developed a pooled high-throughput screen to identify
Autor:
John-Paul Bacik, Nozomi Ando, William C. Thomas, James Z. Chen, JoAnne Stubbe, Jason T. Kaelber, Audrey A. Burnim, F. Phil Brooks
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 75:a14-a14
Autor:
Phil Brooks F 3rd; Harvard University, Department of Chemistry and Chemical Biology, Cambridge, Massachusetts, United States., Davis HC; Harvard University, Department of Chemistry and Chemical Biology, Cambridge, Massachusetts, United States., Wong-Campos JD; Harvard University, Department of Chemistry and Chemical Biology, Cambridge, Massachusetts, United States., Cohen AE; Harvard University, Department of Chemistry and Chemical Biology, Cambridge, Massachusetts, United States.
Publikováno v:
Neurophotonics [Neurophotonics] 2024 Jul; Vol. 11 (3), pp. 035007. Date of Electronic Publication: 2024 Aug 13.
Autor:
Chien MP; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.; Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, Netherlands.; Oncode Institute, Utrecht, Netherlands., Brinks D; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.; Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, Netherlands.; Department of Imaging Physics, Delft University of Technology, Delft, Netherlands., Testa-Silva G; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.; Howard Hughes Medical Institute, Cambridge, MA 02138, USA., Tian H; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA., Phil Brooks F 3rd; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA., Adam Y; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA., Bloxham B; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA., Gmeiner B; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA., Kheifets S; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA., Cohen AE; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA. cohen@chemistry.harvard.edu.; Howard Hughes Medical Institute, Cambridge, MA 02138, USA.
Publikováno v:
Science advances [Sci Adv] 2021 May 05; Vol. 7 (19). Date of Electronic Publication: 2021 May 05 (Print Publication: 2021).