Zobrazeno 1 - 10
of 291
pro vyhledávání: '"F. Perlík"'
Autor:
O, Bartošová, O, Polanecký, R, Šachl, I, Štenglová Netíková, F, Perlík, S, Adámek, R, Lischke, O, Slanař
Publikováno v:
Physiological research. 68(Suppl 1)
The aim of this study was to evaluate the association between OPRM1 and ABCB1 polymorphisms on pain relief with epidural sufentanil in 69 patients after rectosigma resection for cancer. The median number of injections (SD) 2.31 (1.36), IQR=1, require
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f7c24ffaf97b9bdcb93200a28ec73f3e
https://pubmed.ncbi.nlm.nih.gov/31755291
https://pubmed.ncbi.nlm.nih.gov/31755291
Autor:
F, Perlík
Publikováno v:
Vnitrni lekarstvi. 59(7)
Metabolic liver functions are significantly involved in the total clearance of a number of drugs. In liver cirrhosis the reduced drug elimination is a result of the blood flow through the liver, hepatocytes function and volume of hepatic tissue. Phar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::68c17d538e6f021248265b61011f0911
https://pubmed.ncbi.nlm.nih.gov/23909263
https://pubmed.ncbi.nlm.nih.gov/23909263
Publikováno v:
Casopis lekaru ceskych. 146(9)
Polymorphisms in drug metabolizing enzymes are considered as a major factor influencing the incidence of adverse drug reactions or failure of pharmacotherapy. Our aim was to compare the distribution of functional polymorphisms in the genes CYP2D6 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9f106face864ccb9e6c74aaf4bd9e1db
https://pubmed.ncbi.nlm.nih.gov/17966194
https://pubmed.ncbi.nlm.nih.gov/17966194
Publikováno v:
Prague medical report. 107(4)
The majority of human P450 dependent drug metabolism is carried out by polymorphic enzymes which can alter plasma concentration of the pharmacological active substance followed by an enhanced or suppressed pharmacological effect. The response of indi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::13bcd05cbd4a66179c7dd71beeda5684
https://pubmed.ncbi.nlm.nih.gov/17402551
https://pubmed.ncbi.nlm.nih.gov/17402551
Publikováno v:
Prague medical report. 107(3)
The aim of the study was to describe the effect of regulatory changes on the development of statins prescribing in individual districts of the Czech Republic. Retrospective analysis of reimbursed medical prescriptions for statins was based on the dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::32e42106f5ba328feb7a8689bb7355ea
https://pubmed.ncbi.nlm.nih.gov/17385409
https://pubmed.ncbi.nlm.nih.gov/17385409
Publikováno v:
Folia biologica. 52(6)
There exists a marked inter-individual variability of P-glycoprotein expression and activity, which can be of clinical importance due to the large number of drugs that are substrates for the transporter. Previously identified polymorphisms in the MDR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d21aea7c0988013260bf67a8d52be015
https://pubmed.ncbi.nlm.nih.gov/17184596
https://pubmed.ncbi.nlm.nih.gov/17184596
Akademický článek
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Publikováno v:
Casopis lekaru ceskych. 144(4)
Pupil size is mainly controlled by the action of parasympathetic and sympathetic nerves. Measurement of pupil size and reaction to light are important in both experimental and clinical settings.We have established infrared pupilometry using a commerc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::02578e9306be1b84c95980e3506ea006
https://pubmed.ncbi.nlm.nih.gov/15945488
https://pubmed.ncbi.nlm.nih.gov/15945488
Autor:
F, Perlík
Publikováno v:
Casopis lekaru ceskych. 143(2)
Adverse drug reactions represent a common clinical problem. They are partly induced by a large variability in drug response, which results from the complex interplay between pharmacokinetics, pharmacodynamics and other disease-associated factors. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b26fae6de6a4656ee4007ac820b0cc72
https://pubmed.ncbi.nlm.nih.gov/15077574
https://pubmed.ncbi.nlm.nih.gov/15077574
Publikováno v:
Physiological research. 51(4)
Portal-systemic shunting is an important circulatory abnormality in patients with liver cirrhosis. Glyceryl trinitrate (GTN) that is normally subject to first pass elimination, may exhibit higher bioavailability in these patients. This study compares
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7ed8917d4a44570aaf60049d79119f92
https://pubmed.ncbi.nlm.nih.gov/12449441
https://pubmed.ncbi.nlm.nih.gov/12449441