Zobrazeno 1 - 4
of 4
pro vyhledávání: '"F. Patrick McGarry"'
Autor:
Roberta Glynn, Steven Mathieu, David Bauer, Jeevanandam Arumugasamy, Jie Li, Jingyang Wang, Alistair Stewart, Alan Becker, Jinsoo Lim, Elodie Rosinovsky, F. Patrick McGarry, Narayan Chaudhuri, G. Mark Latham, Erkan Baloglu, Adrien F. Soret, Kannan Arunachalam, Jia Liu, Adel Moussa, Benjamin Alexander Mayes
Publikováno v:
Organic Process Research & Development. 19:520-530
A scalable process is described for the synthesis of 2′-C-methylguanosine-5′-[2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)thio]ethyl-N-benzylphosphoramidate], a nucleotide prodrug inhibitor of hepatitis C virus NS5B polymerase. The route features the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59db1becbb4e9c2c9f190d64e71e6d6b
https://doi.org/10.1021/op5003837
https://doi.org/10.1021/op5003837
Autor:
Elodie Rosinovsky, Narayan Chaudhuri, Benjamin Alexander Mayes, Christophe Trochet, Steven Mathieu, G. Mark Latham, Alistair Stewart, Adel Moussa, Jie Li, Jeevanandam Arumugasamy, Alan Becker, Erkan Baloglu, F. Patrick McGarry, Jingyang Wang, David Bauer
Publikováno v:
Organic Process Research & Development. 18:717-724
A synthetic process for 2′-C-methylcytidine-5′-[2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)thio]ethyl-N-benzylphosphoramidate], a nucleotide prodrug inhibitor of hepatitis C virus NS5B polymerase, is described. The route developed was demonstrated on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6560b20a8c693f5283f4af20fa03985c
https://doi.org/10.1021/op500042u
https://doi.org/10.1021/op500042u
Autor:
Steven Mathieu, Adel Moussa, Jingyang Wang, Narayan Chaudhuri, Alistair Stewart, Frederic Jeannot, G. Mark Latham, Christopher P. Hencken, F. Patrick McGarry, Benjamin Alexander Mayes
Publikováno v:
Organic Process Research & Development. 14:1248-1253
A synthetic preparation of methyl 5-chloro-4-fluoro-1H-indole-2-carboxylate, a key intermediate towards phosphoindole inhibitors of HIV non-nucleoside reverse transcriptase, is described. The five-step synthesis involved Boc protection of the commerc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::652b1f65a8b5d87a054125368a49fe7c
https://doi.org/10.1021/op1001808
https://doi.org/10.1021/op1001808
Autor:
Benjamin A. Mayes, Jingyang Wang, Jeevanandam Arumugasamy, Kannan Arunachalam, Erkan Baloglu, David Bauer, Alan Becker, Narayan Chaudhuri, Roberta Glynn, G. Mark Latham, Jie Li, Jinsoo Lim, Jia Liu, Steve Mathieu, F. Patrick McGarry, Elodie Rosinovsky, Adrien F. Soret, Alistair Stewart, Adel Moussa
Publikováno v:
Organic Process Research & Development; Apr2015, Vol. 19 Issue 4, p520-530, 11p