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pro vyhledávání: '"F. Oesch"'
Methyl acrylate (MA) and ethyl acrylate (EA) had previously tested positive for mutagenicity in vitro, but in vivo studies were negative. One of the metabolism pathways of alkyl acrylates is conjugation with glutathione. The glutathione availability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bccae586c2e29041aa19c8e29f9e768
https://refubium.fu-berlin.de/handle/fub188/35846
https://refubium.fu-berlin.de/handle/fub188/35846
Autor:
F Oesch, Jan G. Hengstler
Publikováno v:
Regulatory Toxicology ISBN: 9783642362064
Regulatory Toxicology
Regulatory Toxicology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9d4cbef650811eef1287d2d795b8760
https://doi.org/10.1007/978-3-642-36206-4_71-2
https://doi.org/10.1007/978-3-642-36206-4_71-2
Publikováno v:
Archives of Toxicology
Studies on the metabolic fate of medical drugs, skin care products, cosmetics and other chemicals intentionally or accidently applied to the human skin have become increasingly important in order to ascertain pharmacological effectiveness and to avoi
Publikováno v:
Laryngo- rhino- otologie. 95(7)
Autor:
S Löffler, H. Halfer-Wirkus, W. Porn, F. Oesch, G. Doerjer, E. Lehrbach, H. R. Glatt, Frans Setiabudi, I. Gemperlein-Mertes, J. Herborn, T. Wölfel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2dc012a890064f6a0349022c74ac11a
https://doi.org/10.1159/000412583
https://doi.org/10.1159/000412583
Publikováno v:
Annual Review of Pharmacology and Toxicology. 43:485-520
Although many questions remain unanswered, the general principle of the sequence of events leading to cancer after exposure to genotoxic carcinogens has become increasingly clear. This helps to understand the parameters that influence the shape of th
Akademický článek
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Autor:
F Oesch, Jan G. Hengstler
Publikováno v:
Regulatory Toxicology ISBN: 9783642353734
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c234d6f4760bbcc177c512fd13c65fb5
https://doi.org/10.1007/978-3-642-35374-1_71
https://doi.org/10.1007/978-3-642-35374-1_71
Publikováno v:
Europe PubMed Central
Objectives In lungs of asbestos-exposed persons alveolar and interstitial macrophages are able to release genotoxic substances such as reactive oxygen intermediates. It is unknown whether reactive oxygen intermediates released by macrophages are able
Publikováno v:
Xenobiotica. 30:665-681
1. The effect of cryopreservation on the metabolic capacity of monkey hepatocytes over 4 h in suspension and 24 h in culture was determined. Hepatocytes were diluted in a buffer containing 10% DMSO and frozen in a computer-controlled chamber. 2. Init