Zobrazeno 1 - 10
of 19
pro vyhledávání: '"F. O'kirwan"'
Autor:
Johannes D. Veldhuis, Sinan Caglayan, Bulent O. Yildiz, Ma-Li Wong, Julio Licinio, Alex M. DePaoli, Patricia B. de Miranda, Pinchas Cohen, Liyin Liang, Ronald M. Krauss, Shalender Bhasin, F. O'kirwan, Anthony J. Wagner, Samuel M. McCann, Robert Whitby, Metin Ozata
Publikováno v:
Proceedings of the National Academy of Sciences. 101:4531-4536
Genetic mutations in the leptin pathway can be a cause of human obesity. It is still unknown whether leptin can be effective in the treatment of fully established morbid obesity and its endocrine and metabolic consequences in adults. To test the hypo
Publikováno v:
Molecular Psychiatry. 9:237-251
Both the prototypic tricyclic antidepressant imipramine (IMI) and the herbal product St John's wort (SJW) can be effective in the treatment of major depressive disorder. We studied hypothalamic gene expression in rats treated with SJW or IMI to test
Autor:
Samuel M. McCann, Philip W. Gold, Jonas Hannestad, Ma-Li Wong, Gregory W. Lawson, Nadia Khan, F. O'kirwan, Julio Licinio, Kwok H. Wu, David Elashoff
Publikováno v:
Proceedings of the National Academy of Sciences. 100:14241-14246
In septic shock, reversible cardiac dysfunction starts within 24 h. Myocardial depressant factors are thought to cause myocyte dysfunction, resulting in alterations of intrinsic cardiac function. Nitric oxide is a myocardial depressant factor candida
Publikováno v:
The pharmacogenomics journal. 4(6)
Interethnic differences in cytochrome P450 polymorphism might be responsible, at least in part, for the variations in drug disposition between ethnic groups. Of the various CYP2C9 alleles, CYP2C9*2 and CYP2C9*3 have been reported to have altered cata
Autor:
Kelan G. Tantisira, Barry Merriman, Sarika Thakur, Julio Licinio, Stephen L. Lake, Ma-Li Wong, F. O'kirwan, K. Irizarry, Jepson R, Scott T. Weiss
Publikováno v:
Molecular psychiatry. 9(12)
There are well-replicated, independent lines of evidence supporting a role for corticotropin-releasing hormone (CRH) in the pathophysiology of depression. CRH receptor 1 (CRHR1), which we first mapped in the brain in 1994, has been implicated in the
Autor:
A. dePaoli, Bulent O. Yildiz, Julio Licinio, A. Wagner, Sinan Caglayan, R. M. Krauss, F. O'kirwan, P. de Miranda, M. Ozata, Ma-Li Wong, Johannes D. Veldhuis, S. Bhasinm
Publikováno v:
Clinical Pharmacology & Therapeutics. 75:P11
Background Genetic mutations in the leptin pathway can be a cause of human obesity. We examined the effects of human leptin replacement in the only three adults identified to date who have genetically-based leptin deficiency. Their phenotype consiste
Autor:
Stefan R. Bornstein, David Heber, F. O'kirwan, P. Frost, M. Ehrhart-Bornstein, Ma-Li Wong, Julio Licinio, V. Go, C. Hutson
Publikováno v:
ResearcherID
Dysregulation in corticotropin-releasing hormone (CRH) secretion in the hypothalamus-pituitary-adrenal (HPA) axis may be involved in the etiology of major depressive disorder (MDD). Chronic therapy with standard antidepressant drugs, such as imiprami
Externí odkaz:
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http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000186587400008&KeyUID=WOS:000186587400008
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