Zobrazeno 1 - 10 of 361 pro vyhledávání: '"F. Munro"'
1
Akademický článek
Crosstalk with lung fibroblasts shapes the growth and therapeutic response of mesothelioma cells
Autor: Yakinthi Chrisochoidou, Rajat Roy, Pooyeh Farahmand, Guadalupe Gonzalez, Jennifer Doig, Lukas Krasny, Ella F. Rimmer, Anne E Willis, Marion MacFarlane, Paul H. Huang, Neil O. Carragher, Alison F. Munro, Daniel J. Murphy, Kirill Veselkov, Michael J. Seckl, Miriam F. Moffatt, William O. C. Cookson, Olivier E. Pardo
Publikováno v: Cell Death and Disease, Vol 14, Iss 11, Pp 1-20 (2023)
Abstract Mesothelioma is an aggressive cancer of the mesothelial layer associated with an extensive fibrotic response. The latter is in large part mediated by cancer-associated fibroblasts which mediate tumour progression and poor prognosis. However,
Externí odkaz: https://doaj.org/article/aaf6d7ac3e1a4d1b86de96ee85ac0b92
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3
Akademický článek
Targeting earlier diagnosis: What symptoms come first in Degenerative Cervical Myelopathy?
Autor: Colin F Munro, Ratko Yurac, Zipser Carl Moritz, Michael G Fehlings, Ricardo Rodrigues-Pinto, James Milligan, Konstantinos Margetis, Mark R N Kotter, Benjamin M Davies
Publikováno v: PLoS ONE, Vol 18, Iss 3, p e0281856 (2023)
BackgroundDegenerative cervical myelopathy (DCM) is a common and disabling condition. Early effective treatment is limited by late diagnosis. Conventional descriptions of DCM focus on motor and sensory limb disability, however, recent work suggests t
Externí odkaz: https://doaj.org/article/f7f182f59f3a40bc83f93ffb570c60c4
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4
Akademický článek
Unlocking the transcriptomic potential of formalin-fixed paraffin embedded clinical tissues: comparison of gene expression profiling approaches
Autor: Arran K. Turnbull, Cigdem Selli, Carlos Martinez-Perez, Anu Fernando, Lorna Renshaw, Jane Keys, Jonine D. Figueroa, Xiaping He, Maki Tanioka, Alison F. Munro, Lee Murphy, Angie Fawkes, Richard Clark, Audrey Coutts, Charles M. Perou, Lisa A. Carey, J. Michael Dixon, Andrew H. Sims
Publikováno v: BMC Bioinformatics, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Background High-throughput transcriptomics has matured into a very well established and widely utilised research tool over the last two decades. Clinical datasets generated on a range of different platforms continue to be deposited in public
Externí odkaz: https://doaj.org/article/35931cd60eb849c58eee6a74c308610f
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7
Distinct neuroinflammatory signatures exist across genetic and sporadic ALS cohorts
Autor: Olivia M. Rifai, Judi O’Shaughnessy, Owen R. Dando, Alison F. Munro, Michael D.E. Sewell, Sharon Abrahams, Fergal M. Waldron, Christopher R. Sibley, Jenna M. Gregory
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterised by progressive loss of upper and lower motor neurons. ALS is on a pathogenetic disease spectrum with frontotemporal dementia (FTD), with patients sometimes experiencing
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::30a6117d07ef89750449883a80f227b2
https://doi.org/10.1101/2023.01.19.524561
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8
Targeting earlier diagnosis: What symptoms come first in Degenerative Cervical Myelopathy?
Autor: Colin F. Munro, Ratko Yurac, Zipser Carl Moritz, Michael G. Fehlings, Ricardo Rodrigues-Pinto, James Milligan, Konstantinos Margetis, Mark R. N. Kotter, Benjamin M. Davies
Background Degenerative cervical myelopathy (DCM) is a common and disabling condition. Early effective treatment is limited by late diagnosis. Conventional descriptions of DCM focus on motor and sensory limb disability, however, recent work suggests
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f59f00f169ae446483c9225cec8f6917
https://www.repository.cam.ac.uk/handle/1810/348868
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9
283 AN EXPLORATION OF THE IRISH NATIONAL FRAILTY EDUCATION PROGRAMME ON PRACTICE: A FRAILTY FACILITATOR'S PERSPECTIVE
Autor: F Munro, C Murphy
Publikováno v: Age and Ageing. 51
Background Frailty is associated with a range of adverse outcomes in older adults requiring prevention, early detection and management. Interprofessional collaboration in education and practice can facilitate integrated care for older people in the m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4fad47ab4e4610d459e8f93b3af417e3
https://doi.org/10.1093/ageing/afac218.250
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10
Multiparametric High-Content Cell Painting Identifies Copper Ionophores as Selective Modulators of Esophageal Cancer Phenotypes
Autor: Rebecca E. Hughes, Richard J. R. Elliott, Xiaodun Li, Alison F. Munro, Ashraff Makda, Roderick N. Carter, Nicholas M. Morton, Kenji Fujihara, Nicholas J. Clemons, Rebecca Fitzgerald, J. Robert O’Neill, Ted Hupp, Neil O. Carragher
Publikováno v: Hughes, R E, Elliott, R J R, Li, X, Munro, A F, Makda, A, Carter, R N, Morton, N M, Fujihara, K, Clemons, N J, Fitzgerald, R, O’neill, J R, Hupp, T & Carragher, N O 2022, ' Multiparametric High-Content Cell Painting Identifies Copper Ionophores as Selective Modulators of Esophageal Cancer Phenotypes ', Acs chemical biology . https://doi.org/10.1021/acschembio.2c00301
Esophageal adenocarcinoma is of increasing global concern due to increasing incidence, a lack of effective treatments, and poor prognosis. Therapeutic target discovery and clinical trials have been hindered by the heterogeneity of the disease, the la
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ae1b81ebfac4d9ae464d548058df3c
https://hdl.handle.net/20.500.11820/912bf260-81ba-4eb2-816a-27ffa0dbfa9d
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