Zobrazeno 1 - 10
of 50
pro vyhledávání: '"F. Marquart"'
Autor:
Yanik Weber, Desirée Böck, Anastasia Ivașcu, Nicolas Mathis, Tanja Rothgangl, Eleonora I. Ioannidi, Alex C. Blaudt, Lisa Tidecks, Máté Vadovics, Hiromi Muramatsu, Andreas Reichmuth, Kim F. Marquart, Lucas Kissling, Norbert Pardi, Martin Jinek, Gerald Schwank
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Prime editing is a highly versatile genome editing technology that enables the introduction of base substitutions, insertions, and deletions. However, compared to traditional Cas9 nucleases prime editors (PEs) are less active. In this study
Externí odkaz:
https://doaj.org/article/0aff369579524b25ad7f5eb7c077ffae
Autor:
Kim F. Marquart, Ahmed Allam, Sharan Janjuha, Anna Sintsova, Lukas Villiger, Nina Frey, Michael Krauthammer, Gerald Schwank
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Base editors enable precise genetic alterations but vary in efficiency at different loci. Here the authors analyse ABEs and CBEs at over 28,000 integrated sequences to train BE-DICT, a machine learning model capable of predicting base editing outcome
Externí odkaz:
https://doaj.org/article/c9632ae8e3554eb0a6f6c3e3694e3ef8
Autor:
Keagan M. Ringling, Len F. Marquart
Publikováno v:
Frontiers in Sustainable Food Systems, Vol 4 (2020)
Food and agriculture professionals strive to feed the growing population diets that maintain human health and minimize environmental impacts. Recently, global organizations such as the World Health Organization and the Food and Agricultural Organizat
Externí odkaz:
https://doaj.org/article/f727acd38bbf41ce8f5a73df1deaf967
Autor:
Tanja Rothgangl, Martina Hruzova, Ralph Gnannt, Nadja Aeberhard, Lucas Kissling, Hiu Man Grisch-Chan, Sven Klassa, Nicole Rimann, Kim F. Marquart, Eleonora Ioannidi, Anja Wolf, Christian Kupatt, Xaver Sidler, Johannes Häberle, Gerald Schwank, Beat Thöny
One challenge for liver-directed gene therapy is sufficient vector delivery to the target tissue while minimizing loss of the applied vector dose to other tissues. Infusion via peripheral veins is the least invasive approach; however, it results in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16e29a86e47747a7ab0e74f492719f8e
https://doi.org/10.1101/2023.04.05.535660
https://doi.org/10.1101/2023.04.05.535660
Publikováno v:
West European Politics, 44(5-6), 1314-1328. Routledge
Goldberg, A C, Gattermann, K, Marquart, F, Brosius, A & de Vreese, C H 2021, ' European solidarity in times of crisis : the role of information and media use ', West European Politics, vol. 44, no. 5-6, pp. 1314-1328 . https://doi.org/10.1080/01402382.2021.1884398
Goldberg, A C, Gattermann, K, Marquart, F, Brosius, A & de Vreese, C H 2021, ' European solidarity in times of crisis : the role of information and media use ', West European Politics, vol. 44, no. 5-6, pp. 1314-1328 . https://doi.org/10.1080/01402382.2021.1884398
COVID-19 has important implications for European solidarity. In this study, it is proposed to consider the role of information and media use for citizens’ attitudes towards European solidarity given the accelerated information supply alongside an i
Publikováno v:
Nutrients, Vol 5, Iss 6, Pp 2093-2113 (2013)
Dietary fiber may contribute to satiety. This study examined the effect of two dietary fiber characteristics, small intestinal contents viscosity and large intestinal fermentability, on satiety-and adiposity-related hormones in rats. Diets contained
Externí odkaz:
https://doaj.org/article/388e6ed5c6b9439b8e1cd78134cc3bae
Publikováno v:
Nutrition in Exercise and Sport ISBN: 9780367813499
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5870fe62955b385388a55b9f223aa1e4
https://doi.org/10.1201/9780367813499-23
https://doi.org/10.1201/9780367813499-23
Akademický článek
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Akademický článek
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Autor:
Simon, Fischer, Kim F, Marquart, Lisa A, Pieper, Juergen, Fieder, Martin, Gamer, Ingo, Gorr, Patrick, Schulz, Harald, Bradl
Publikováno v:
Biotechnology and Bioengineering
In recent years, coherent with growing biologics portfolios also the number of complex and thus difficult‐to‐express (DTE) therapeutic proteins has increased considerably. DTE proteins challenge bioprocess development and can include various ther