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The beach degradation and sustainable management of the sandy coast: the Yilan coast of Northeastern Taiwan

Autor: H. M. Lin, Y. T. Huang, F. M. Chu

Publikováno v: Island Sustainability II.

The purpose of this research is to improve the knowledge of citizens towards the Yilan coastal area. The basic ideas behind this project are to reduce the degree of usage of limited natural resources and to preserve the coastal area. First, it is imp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6ea618f8dbbcffffd7107291c11839b3
https://doi.org/10.2495/islands120161

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[Three dimensional quantitative structure-activity relationship of heterocyclic-compounds with di-tert-bultylphenyl inhibitors]

Autor: A P, Bai, Z R, Guo, F M, Chu

Publikováno v: Yao xue xue bao = Acta pharmaceutica Sinica. 36(5)

To quatitatively disclose the relationship between activity and structure of a new class of COX-II inhibitors containing dialkylphenyl-linked heterocyclic moieties.Seventeen COX-II inhibitors from literature as a training set were investigated with t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6fc7ef1d5b871b1c9b6c0ab4142206bc
https://pubmed.ncbi.nlm.nih.gov/12584856

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[Synthesis of triphenylethylene with aliphatic cyclic moiety and its antagonism on estrogen receptor]

Autor: B L, Xu, Z R, Guo, N G, Wang, M Z, Guan, X T, Liang, F M, Chu

Publikováno v: Yao xue xue bao = Acta pharmaceutica Sinica. 36(3)

In order to improve the biological activity and reduce the side effects and toxicity, a series of novel estrogen receptor antagonists were designed.The key triphenylethylene intermediates were obtained by the McMurry reaction. The target compounds we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f8af893e9b49414e8e8680ac84524785
https://pubmed.ncbi.nlm.nih.gov/12580083

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[Studies on retinoids. IV. Design, synthesis and structure-activity relationships of di-t-butylphenyl compounds]

Autor: Z R, Guo, Q Z, Liu, F M, Chu, M M, Wang, S Q, Pi, G Z, Yang, R, Han, L J, Xia, X Q, He

Publikováno v: Yao xue xue bao = Acta pharmaceutica Sinica. 32(11)

Retinoic acid and its analogues play important roles in modulating cell growth, differentiation, immunity and apoptosis. Clinically they are used for cancer chemoprevention and chemotherapy. Based upon the moiety of 3,5-di-t-butyl-4-hydroxy phenyl ri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d40f1d13eb9b939588d4f8e0a2d9b78d
https://pubmed.ncbi.nlm.nih.gov/11596202

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Phase I study of CNTO 95, a fully human monoclonal antibody to αv integrins, docetaxel, and prednisone in hormone refractory prostate cancer patients (HRPCP)

Autor: B. Foster, Z. Lang, Joel Picus, M. Mata, F. M. Chu, R. A. Beckman, C. Kopacynski, Robert Dreicer

Publikováno v: Journal of Clinical Oncology. 25:15595-15595

15595 Background: CNTO 95 has demonstrated preclinical antitumor activity through binding to multiple av integrins, resulting in growth inhibition indirectly through anti-angiogenic effects as well as directly by inhibiting tumor cell proliferation.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c58411ee013413acdb9f8f475dea0958
https://doi.org/10.1200/jco.2007.25.18_suppl.15595

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Akademický článek

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[Studies on antipeptic ulcer agents: the synthesis and QSAR analysis of heterocycle aldehyde N4-substituted phenyl(thio)semicarbazones]

Autor: Z R, Guo, G Z, Yang, F M, Chu, S R, Zhang, Y W, Yu

Publikováno v: Yao xue xue bao = Acta pharmaceutica Sinica. 24(11)

Forty-five condensation products of furan-, pyrrole-, and N-methyl pyrrole-alpha-carboaldehyde with N4-3-or 4-substituted phenyl semicarbazides and thiosemicarbazides were designed and synthesized to optimize the antiulcer activity. Quantitative stru

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::90b7d786e67e0c8dea32adaa399dbcb1
https://pubmed.ncbi.nlm.nih.gov/2618679

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