National multicentric evaluation of quality of pathology reports for rectal cancer in France in 2016

Autor: Anne Rullier, Céline Bazille, M. Desrousseaux, A. Daubech, Catherine Julie, F. Thélu, F. Le Pessot, B. Turlin, S. Stanislas, M.-S. Bordier, Armelle Bardier, C. Boutanos, Marie-Hélène Laverriere, R.-P. Eyremandi, A. Rousseau, T. Lazure, Janick Selves, Frédéric Bibeau, Nathalie Guedj, Magali Svrcek, M. Capdepont, Flora Poizat, B. Bonhomme, A. Demoures

Publikováno v: Virchows Archiv
Virchows Archiv, Springer Verlag, 2019, 474 (5), pp.561-568. ⟨10.1007/s00428-019-02534-8⟩

International audience; The quality of pathologic assessment of rectal cancer specimens is crucial for treatment efficiency and survival. The Royal College of Pathologists (RCP) recommends evaluating the quality of the pathology report in routine pra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aac1f7d94ed30da7902adcfed18b4617
https://hal.umontpellier.fr/hal-02431858

Le laboratoire de Génétique Somatique des Tumeurs du CHU de Rouen

Autor: A. Lamy, J.C. Sabourin, Thierry Frebourg, F. Le Pessot

Publikováno v: Annales de Pathologie. 27:122-125

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b854eaa27b0fdc4e3c19f969746f6394
https://doi.org/10.1016/s0242-6498(07)92894-1

Clinical relevance of KRAS mutation detection in metastatic colorectal cancer treated by Cetuximab plus chemotherapy

Autor: A. Lamy, Jean-Christophe Sabourin, Audrey Killian, Pierre Michel, Thierry Frebourg, L Bastit, F. Le Pessot, Bernard Paillot, Richard Sesboüé, F. Di Fiore, A.-M. Queuniet, Francis Michot, M.P. Galais, F. Blanchard, Jean-Jacques Tuech, Françoise Charbonnier

Publikováno v: British Journal of Cancer

The predictive value of KRAS mutation in metastatic colorectal cancer (MCRC) patients treated with cetuximab plus chemotherapy has recently been suggested. In our study, 59 patients with a chemotherapy-refractory MCRC treated with cetuximab plus chem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6565613bf83a681b53d8a6bb5da508
https://doi.org/10.1038/sj.bjc.6603685

Cleft lip/palate and CDH1/E-cadherin mutations in families with hereditary diffuse gastric cancer

Autor: Julia B. Winston, S Lejeune Dumoulin, Michael Lovett, Sérgio Castedo, Carla Oliveira, Juanliang Cai, Stéphanie Baert-Desurmont, Michel Scotté, C Marroni, Cosette Martin, José Carlos Machado, Michel Vekemans, Fátima Carneiro, Sylvie Manouvrier, Cláudio Osmar Pereira Alexandre, Rachid Karam, C. Graziadio, J P Triboulet, F Le Pessot, A Hedouin, A Hartmann, T Attié, P Hochain, Raquel Seruca, Ph Pellerin, Thierry Frebourg, Martine Blayau, Ethylin Wang Jabs

Publikováno v: Journal of Medical Genetics. 43:138-142

We report the association of CDH1/E‐cadherin mutations with cleft lip, with or without cleft palate (CLP), in two families with hereditary diffuse gastric cancer (HDGC). In each family, the CDH1 mutation was a splicing mutation generating aberrant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3b0d8cec39479ba7d720e0f68f999c5
https://doi.org/10.1136/jmg.2005.031385

TP53 mutations predict disease control in metastatic colorectal cancer treated with cetuximab-based chemotherapy

Autor: Gaëlle Bougeard, F. Boissière, Jean-Jacques Tuech, J.-C. Sabourin, Frédéric Bibeau, Marc Ychou, David Tougeron, Françoise Charbonnier, Pierre Michel, F. Le Pessot, Aude Lamy, Thierry Frebourg, F. Di Fiore, Alice Oden-Gangloff, F. Blanchard

Publikováno v: British Journal of Cancer
British Journal of Cancer, 2009, 100 (8), pp.1330-1335. ⟨10.1038/sj.bjc.6605008⟩
British Journal of Cancer, Cancer Research UK, 2009, 100 (8), pp.1330-1335. ⟨10.1038/sj.bjc.6605008⟩

International audience; Recent studies have suggested that activation of the EGFR pathway leads to malignant transformation only if the p53 protein is inactivated. Therefore, we evaluated the impact of TP53 mutations on cetuximab-based chemotherapy (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ccc61d0e9fb18d13febbdae2475895c
https://pubmed.ncbi.nlm.nih.gov/19367287