Zobrazeno 1 - 10
of 163
pro vyhledávání: '"F. Lanoue"'
Publikováno v:
Journal of Materials Research and Technology, Vol 27, Iss , Pp 4772-4786 (2023)
A new L-PBF process is proposed to manufacture, from a single powder chemically activated by pure hot water, parts comprising in selected areas of space, a ceramic or a metal alloy. The chemical activation of the starting alloy powder, the melting an
Externí odkaz:
https://doaj.org/article/798fa154a24e4feaaecb95458bcc8ea5
Publikováno v:
Neurotoxicity research. 36(1)
Neurodegeneration in diabetic retina has been widely considered as initiating factor that may lead to vascular damage, the classical hallmark of diabetic retinopathy. Diabetes induced altered glutamate metabolism in the retina, especially through glu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0418a4a608ee87c280056f236237d9d9
https://pubmed.ncbi.nlm.nih.gov/30830678
https://pubmed.ncbi.nlm.nih.gov/30830678
Akademický článek
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Publikováno v:
Brain research bulletin. 144
Muller glial cells are highly metabolic active cells that compensate for the high energy demand of retinal neurons. It has been believed that glucose provides the energy needs by the complete oxidation within Muller cells. However, numerous studies i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc4d25e8a470f6cb816c62e0d23a0536
https://pubmed.ncbi.nlm.nih.gov/30503222
https://pubmed.ncbi.nlm.nih.gov/30503222
Publikováno v:
Neurochemistry International. 59:656-663
Glutamate released from retinal neurons during neurotransmission is taken up by retinal Müller cells, where much of the amino acid is subsequently amidated to glutamine or transaminated to α-ketoglutarate for oxidation. Müller cell glutamate level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c153e8de34bf0bcbc3e4ca72370da9c0
https://doi.org/10.1016/j.neuint.2011.06.010
https://doi.org/10.1016/j.neuint.2011.06.010
Publikováno v:
Metabolic Brain Disease. 26:195-202
Glutamine synthetase (GS), a Müller cell specific enzyme in the retina, is the key enzyme involve in glutamate metabolism. The goal of this study was to investigate the expression and regulation of GS by insulin in the cultured rat retinal Müller c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::004d80d80998c5b854fe7929b03b1438
https://doi.org/10.1007/s11011-011-9245-y
https://doi.org/10.1007/s11011-011-9245-y
Publikováno v:
Journal of Neurochemistry. 117:309-320
Excised retinas from euglycemic and diabetic Sprague-Dawley rats were studied to evaluate differences in glutamate metabolism related to diabetes. Reports suggest, neuronal cell death possibly caused by glutamate excitotoxicity, is an early consequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6a9aeb5487a2a077fc9ac20fedeb4a9
https://doi.org/10.1111/j.1471-4159.2011.07206.x
https://doi.org/10.1111/j.1471-4159.2011.07206.x
Autor:
Alistair J. Barber, Heather D. VanGuilder, Thomas W. Gardner, Kruti M. Patel, Robert M. Brucklacher, Sarah K. Bronson, Kathryn F. LaNoue, Scot R. Kimball, Willard M. Freeman, Cheng-mao Lin, David A. Antonetti, Georgina V. Bixler
Publikováno v:
The Pharmacogenomics Journal. 10:385-395
Biomarkers that can be measured in preclinical models in a high-throughput, reproducible manner offer the potential to increase the speed and efficacy of drug development. Development of therapeutic agents for many conditions is hampered by the limit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dc3d6dd8d8a7775430b95fcbdbb11f7
https://doi.org/10.1038/tpj.2009.60
https://doi.org/10.1038/tpj.2009.60
Autor:
John M. Flanagan, Keith C. Cheng, Kathryn F. LaNoue, William J. Zinnanti, Jelena Lazovic, Gregg E. Homanics, Kristen J. Skvorak, Harbhajan S Paul, Kathleen Griffin, Maria C. Bewley
Publikováno v:
Brain
Maple syrup urine disease (MSUD) is an inherited disorder of branched-chain amino acid metabolism presenting with life-threatening cerebral oedema and dysmyelination in affected individuals. Treatment requires life-long dietary restriction and monito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587e5d0c0ec9cede9f0154c0c9136945
http://europepmc.org/articles/PMC2668944
http://europepmc.org/articles/PMC2668944
Autor:
Keith C. Cheng, Stephen I. Goodman, Ian A. Simpson, Russell E. Jacobs, James P. O'Callaghan, Michael Woontner, Jelena Lazovic, Cathy Housman, James R. Connor, William J. Zinnanti, Kathryn F. LaNoue
Publikováno v:
Journal of Clinical Investigation. 117:3258-3270
Glutaric acidemia type I (GA-I) is an inherited disorder of lysine and tryptophan metabolism presenting with striatal lesions anatomically and symptomatically similar to Huntington disease. Affected children commonly suffer acute brain injury in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4337b4fc649f683a3f7a9980873bfdbe
https://doi.org/10.1172/jci31617
https://doi.org/10.1172/jci31617