Zobrazeno 1 - 10 of 12 pro vyhledávání: '"F. L. Fort"'
1
Analysis for loss of heterozygosity (LOH) of p53 allele in tumors derived from p53+/- and CD-1 mice following repeated subcutaneous injections of solutions containing antioxidants
Autor: A F, Youssef, F, Borellini, D, Jacobson-Kram, F L, Fort
Publikováno v: Environmental and molecular mutagenesis. 37(1)
Genomic DNA was isolated from subcutaneous masses observed in CD-1 and p53+/- heterozygous mice during the course of carcinogenicity studies in the vehicle control groups. These masses resulted after daily subcutaneous injection of an antioxidant veh
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4a035015fb9b6e7e292100c508deecea
https://pubmed.ncbi.nlm.nih.gov/11170239
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2
Mechanism for species-specific induction of Leydig cell tumors in rats by lansoprazole
Autor: G. D. Hodgen, Masaki Yamamoto, T. Suzuki, T. Hamashima, T. Kitazaki, Shuzo Sato, F. L. Fort, T. Ando, H. Miyajima, M. C. Mahony
Publikováno v: Fundamental and applied toxicology : official journal of the Society of Toxicology. 26(2)
Lansoprazole is a substituted benzimidazole which inhibits gastric acid secretion by inhibiting the hydrogen-potassium ATPase (proton pump) in the parietal cell. The finding of Leydig cell hyperplasia and Leydig cell tumors in 2-year oral studies in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3eb972865d8b2912affbdd9df9e8c1f
https://pubmed.ncbi.nlm.nih.gov/7589908
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3
Buflomedil: one-year oral safety evaluation in rats
Autor: S. A. Ruckman, D. R. Patterson, R. L. Gregson, F. L. Fort
Publikováno v: Drug and chemical toxicology. 16(2)
Buflomedil was given as a dietary mix to Sprague-Dawley Rats for one year at dosages of 0, 25, 75, and 400 mg/kg/day. Each group contained thirty rats of each sex, of which 10/sex/group were preassigned to a withdrawal period of 3 months following th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b0e3f5dd843d170b0e4d782223d8de3
https://pubmed.ncbi.nlm.nih.gov/8486099
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6
Buflomedll: Three Month Intravenous Safety Evaluation in Rats
Autor: J. W. Kesterson, S. Tekeli, I. A. Heyman, P. K. Cusick, F. L. Fort, J. P. Lewkowski
Publikováno v: Drug and Chemical Toxicology. 5:401-414
Buflomedil was administered intravenously to rats at dosages of 1, 4, 12 or 30 mg/kg/day for up to three months. The no-adverse-effect dosage was considered to be 12 mg/kg/day. At 30 mg/kg/day several deaths and clinical signs, including ataxia, decr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d68d65362c91c65399b4566a81c728d0
https://doi.org/10.3109/01480548208993192
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7
Terazosin: Intravenous Safety Evaluation in Rats
Autor: F. L. Fort, J. W. Kesterson, K.R. Majors, P. K. Cusick, S. Tekeli, I. A. Heyman
Publikováno v: Drug and Chemical Toxicology. 7:435-449
Terazosin, an alpha-adrenergic antagonist, was administered as a 15 mg/ml solution to rats intravenously at a rate of 2 ml/min. Under these conditions the LD50 was 277 mg/kg for males and 293 mg/kg for females. When administered daily for 1 month at
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92abcc17f0dea9219972257d81203cf9
https://doi.org/10.3109/01480548408994211
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8
Phototoxicity of tin protoporphyrin, tin mesoporphyrin, and tin diiododeuteroporphyrin under neonatal phototherapy conditions
Autor: F L, Fort, J, Gold
Publikováno v: Pediatrics. 84(6)
Tin metalloporphyrins are being considered as therapeutic agents for neonatal hyperbilirubinemia, and it is possible that concurrent exposure to phototherapy will occur during their use. Euthymic hairless guinea pigs, Crl:IAF(HA)BR, were given daily
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::90f59572de2080911c58201faa741d1c
https://pubmed.ncbi.nlm.nih.gov/2531365
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9
Endometrial estrogen and progesterone receptors in a uterus didelphys
Autor: J C, Tsibris, F L, Fort, B, Cantor, S R, Gelman, F C, Riggall, W N, Spellacy
Publikováno v: The Journal of reproductive medicine. 24(4)
A 23-year-old woman with a uterus didelphys and a totally occluded left tube had a hysterectomy one year after having a child. Endometrial estrogen and progesterone receptors, both cytoplasmic and nuclear, were determined in five longitudinal section
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b698a90b569f07cc30ac7837f22178ce
https://pubmed.ncbi.nlm.nih.gov/7373604
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10
Heinz bodies, methemoglobinemia, and hemolytic anemia induced in rats by 3-amino-1-[m-(trifluoromethyl)phenyl]-2-pyrazoline
Autor: F L, Fort, M C, Pratt, G W, Carter, J P, Lewkowski, I A, Heyman, P K, Cusick, J W, Kesterson
Publikováno v: Fundamental and applied toxicology : official journal of the Society of Toxicology. 4(2 Pt 1)
Sprague-Dawley CD strain rats were given 18, 35, 70, or 140 mg/kg/day of 3-amino-1-[m-(trifluoromethyl)phenyl]-2-pyrazoline by gavage for 2 weeks. Heinz bodies were seen in the erythrocytes of rats given 140 mg/kg/day. Dose-related increases in methe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5745473fec5533ffda9c8222ce0499f9
https://pubmed.ncbi.nlm.nih.gov/6427045
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