Zobrazeno 1 - 10
of 127
pro vyhledávání: '"F. L. Douglas"'
Autor:
F. L. Douglas, H. P. Dustan, Martha N. Hill, S. Steigerwalt, Louis R. Caplan, C. L. Curry, W. Frishman, Reginald L. Washington, N. B. Shulman, A. C. De Leon
Publikováno v:
Circulation. 85(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5e8fc63fead62cb289a8f371b4afa18
https://pubmed.ncbi.nlm.nih.gov/1735179
https://pubmed.ncbi.nlm.nih.gov/1735179
Publikováno v:
Pharmaceutical research. 9(2)
Very little information is available on the permeability of the blood-brain barrier (BBB) to small polar drugs in chronic hypertension. The blood and cerebrospinal fluid (CSF) pharmacokinetics of libenzapril (LZP), a potent angiotensin converting enz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ba1cbbd6b20bf3d44e77b426345e089
https://pubmed.ncbi.nlm.nih.gov/1553348
https://pubmed.ncbi.nlm.nih.gov/1553348
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 19(5)
Using isolated rat hepatocytes, the in vitro intrinsic hepatic clearance of three drugs, namely, antipyrine (AP), propranolol (P), and CGS 13429 was determined. The hepatic extraction ratios of AP, P, and CGS 13429 were then calculated to be 0.10, 0.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::224fed023b1d86d405cc538b024a2d8b
https://pubmed.ncbi.nlm.nih.gov/1686248
https://pubmed.ncbi.nlm.nih.gov/1686248
Autor:
K. H. Antonin, Michael H. Schwenk, F L Douglas, P Etienne, P. R. Bieck, B. Mühlbauer, W M Coram
Publikováno v:
European journal of clinical pharmacology. 40(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::269d3ef2e3c9ef18f95a6c7ad42fb885
https://pubmed.ncbi.nlm.nih.gov/2050185
https://pubmed.ncbi.nlm.nih.gov/2050185
Autor:
A, Rakhit, S K, Kuwahara, D R, Jones, V F, Soliman, A N, Kotake, T D, Oglesby, J W, Wasley, S L, Tripp, F L, Douglas
Publikováno v:
Pharmaceutical research. 7(10)
The o-naphthoquinone derivative, CGS 8515 (I), is a potent inhibitor (IC50, 0.1 microM) of 5-lipoxygenase, but its therapeutic potential is compromised by a short plasma half-life (22 min) and extremely poor oral bioavailability (less than 2%). Poor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::edfdcc0a921b34fc064603372d62f985
https://pubmed.ncbi.nlm.nih.gov/2281039
https://pubmed.ncbi.nlm.nih.gov/2281039
Publikováno v:
The American journal of clinical nutrition. 51(4)
The effect of magnesium supplementation on blood pressure, erythrocyte cation metabolism, and serum lipids was evaluated in 13 patients with mild hypertension. After randomization and a 3-wk placebo run-in period, seven patients received 40 mmol Mg a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9d9e909085c7394c8669b81eafe5e16
https://pubmed.ncbi.nlm.nih.gov/2181860
https://pubmed.ncbi.nlm.nih.gov/2181860
Autor:
T. A. Burke, A V Schaffer, J Peppard, T Viswanathan, F L Douglas, Young D. Kim, J S Fomsgaard, M.R Danchak, Adam K. Myers
Publikováno v:
Anesthesia & Analgesia. 74:38
Neutralization of heparin anticoagulation by protamine produces catastrophic hemodynamic reactions in some patients. Using a canine model, we tested effects of thromboxane synthetase inhibition (CGS-13080) and glucocorticoid pretreatment on the cardi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5446ba44763361f6b47f56fa3b585903
https://doi.org/10.1213/00000539-199201000-00007
https://doi.org/10.1213/00000539-199201000-00007
Publikováno v:
Hypertension. 8:298-302
Agonists of dopamine receptors can lower blood pressure by vasodilation through action on dopamine1 receptors, inhibition of sympathetic nerve activity by action on dopamine2 receptors, or actions in the central nervous system. Fenoldopam, a selectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0922bc6434c69a3ec0dc39759cdbefab
https://doi.org/10.1161/01.hyp.8.4.298
https://doi.org/10.1161/01.hyp.8.4.298
Publikováno v:
Circulation. 76:1312-1318
Activation of dopamine1 (DA1) receptors relaxes vascular smooth muscle, especially in the renal vascular bed. Fenoldopam, the first selective DA1-receptor agonist that can be administered to man, was infused intravenously in 17 patients with essentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e96a841f99847eed0eda63515477b2f6
https://doi.org/10.1161/01.cir.76.6.1312
https://doi.org/10.1161/01.cir.76.6.1312
Autor:
Tadić, Zoran1 t.albolabris@gmail.com
Publikováno v:
Comparative Cognition & Behavior Reviews. 2023, Vol. 18, p95-120. 26p.