Zobrazeno 1 - 10
of 237
pro vyhledávání: '"F. Kunst"'
Autor:
Roni F. Kunst, Isabelle Bolt, Rychon D.J. van Dasselaar, Bart A. Nijmeijer, Ulrich Beuers, Ronald P.J. Oude Elferink, Stan F.J. van de Graaf
Publikováno v:
JHEP Reports, Vol 6, Iss 1, Pp 100917- (2024)
Background & Aims: Intestine-restricted inhibitors of the apical sodium-dependent bile acid transporter (ASBT, or ileal bile acid transporter) are approved as treatment for several inheritable forms of cholestasis but are also associated with abdomin
Externí odkaz:
https://doaj.org/article/9b3c1ec91c60416aac41d256534c3c20
Autor:
Roni F. Kunst, Dirk R. de Waart, Frank Wolters, Suzanne Duijst, Esther W. Vogels, Isabelle Bolt, Joanne Verheij, Ulrich Beuers, Ronald P.J. Oude Elferink, Stan F.J. van de Graaf
Publikováno v:
JHEP Reports, Vol 4, Iss 11, Pp 100573- (2022)
Background & Aims: Non-absorbable inhibitors of the apical sodium-dependent bile acid transporter (ASBT; also called ileal bile acid transporter [IBAT]) are recently approved or in clinical development for multiple cholestatic liver disorders and lea
Externí odkaz:
https://doaj.org/article/44bd0d993371444b94902a2e94c0bc06
Housing Temperature Influences Atypical Antipsychotic Drug‐Induced Bone Loss in Female C57BL/6J Mice
Publikováno v:
JBMR Plus, Vol 5, Iss 10, Pp n/a-n/a (2021)
ABSTRACT Atypical antipsychotic (AA) drugs, such as risperidone, are associated with endocrine and metabolic side effects, including impaired bone mineral density (BMD) acquisition and increased fracture risk. We have previously shown that risperidon
Externí odkaz:
https://doaj.org/article/377baabe70224c96bc6ba75ffa29d884
Autor:
Audrie L. Langlais, Rebecca V. Mountain, Roni F. Kunst, Deborah Barlow, Karen L. Houseknecht, Katherine J. Motyl
Publikováno v:
Biochimie. Elsevier
Antipsychotic drugs are prescribed to a wide range of individuals to treat mental health conditions including schizophrenia. However, antipsychotic drugs cause bone loss and increase fracture risk. We previously found that the atypical antipsychotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d5fb0acbbc6be79250c750d36a5c6de
https://doi.org/10.1016/j.biochi.2023.05.002
https://doi.org/10.1016/j.biochi.2023.05.002
Autor:
Seth M. Steinberg, Anthony J. Murgo, William D. Figg, Vitaliy Pishchik, G. Aaron Chen, Julie A. Hong, Ana Hancox, Tricia F. Kunst, Xinmin Li, Ming Zhao, Dao M. Nguyen, Maria R. Fischette, David S. Schrump
Purpose: The DNA methylation paradox, manifested as derepression of cancer-testis antigens, and silencing of tumor suppressors during malignant transformation, provides the rationale for the utilization of chromatin remodeling agents for cancer thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::882f9fc79a7ff61fe6b4d2aa8704df79
https://doi.org/10.1158/1078-0432.c.6518526.v1
https://doi.org/10.1158/1078-0432.c.6518526.v1
Autor:
Seth M. Steinberg, Anthony J. Murgo, William D. Figg, Vitaliy Pishchik, G. Aaron Chen, Julie A. Hong, Ana Hancox, Tricia F. Kunst, Xinmin Li, Ming Zhao, Dao M. Nguyen, Maria R. Fischette, David S. Schrump
Supplementary Figure 1 from Phase I Study of Decitabine-Mediated Gene Expression in Patients with Cancers Involving the Lungs, Esophagus, or Pleura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a9f335f1e214fae11ec131f72ab38a9
https://doi.org/10.1158/1078-0432.22441464
https://doi.org/10.1158/1078-0432.22441464
Autor:
Seth M. Steinberg, Anthony J. Murgo, William D. Figg, Vitaliy Pishchik, G. Aaron Chen, Julie A. Hong, Ana Hancox, Tricia F. Kunst, Xinmin Li, Ming Zhao, Dao M. Nguyen, Maria R. Fischette, David S. Schrump
Supplementary Table 1 from Phase I Study of Decitabine-Mediated Gene Expression in Patients with Cancers Involving the Lungs, Esophagus, or Pleura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::056e62cb7b06f5ff10351900587f6b17
https://doi.org/10.1158/1078-0432.22441461.v1
https://doi.org/10.1158/1078-0432.22441461.v1
Publikováno v:
Gut. BMJ Publishing Group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f21566c511b2602a1b92dd93f909e5ef
https://doi.org/10.1136/gutjnl-2021-326452
https://doi.org/10.1136/gutjnl-2021-326452
Housing Temperature Influences Atypical Antipsychotic Drug-Induced Bone Loss in Female C57BL/6J Mice
Publikováno v:
JBMR Plus
JBMR Plus, Vol 5, Iss 10, Pp n/a-n/a (2021)
JBMR Plus, 5(10):e10541. Wiley-Blackwell Publishing Ltd
JBMR Plus, Vol 5, Iss 10, Pp n/a-n/a (2021)
JBMR Plus, 5(10):e10541. Wiley-Blackwell Publishing Ltd
Atypical antipsychotic (AA) drugs, such as risperidone, are associated with endocrine and metabolic side effects, including impaired bone mineral density (BMD) acquisition and increased fracture risk. We have previously shown that risperidone causes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9887c595fb3cbf388438c9d4560f3c53
https://doi.org/10.1002/jbm4.10541
https://doi.org/10.1002/jbm4.10541
Autor:
Udo Rudloff, Christy Arrowood, Cara M. Kenney, Tricia F. Kunst, Santhana Webb, Edward J. Kim, Niharika B. Mettu, Devisser Christina, Seth M. Steinberg
Publikováno v:
Investigational new drugs, vol 39, iss 3
Investigational New Drugs
Investigational New Drugs
SummaryBackground Preclinical evidence has suggested that a subset of pancreatic cancers with the G12R mutational isoform of the KRAS oncogene is more sensitive to MAPK pathway blockade than pancreatic tumors with other KRAS isoforms. We conducted a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9017c18e7dd9e6c059316e49d0d8915e
https://escholarship.org/uc/item/3520819s
https://escholarship.org/uc/item/3520819s