Zobrazeno 1 - 10
of 134
pro vyhledávání: '"F. Kozjek"'
Publikováno v:
International Journal of Pharmaceutics. 215:147-152
The pharmacokinetic parameters of nitrendipine were determined in 40 healthy male volunteers and a very high degree of intersubject variability was observed (CV = 39-71%). Since the distribution of nitrendipine to erythrocytes could influence the ove
Publikováno v:
Biopharmaceutics & Drug Disposition. 20:183-191
Following a single oral administration of ciprofloxacin, norfloxacin, pefloxacin and ofloxacin preparations to healthy volunteers simultaneously collected, saliva and plasma 4-fluoroquinolone concentrations were assayed by HPLC. Pharmacokinetic prope
Publikováno v:
European Journal of Pharmaceutical Sciences. 5:163-169
The application of a two-level back propagation type of neural network has been demonstrated for studying and optimization of diclofenac sodium dissolution from sustained release matrix tablets. The effects of three formulation components (cetyl alco
Publikováno v:
International Journal of Pharmaceutics. 99:79-82
The ionisation constant p K a for N 2 -acetylacyclovir was determined by a spectrophotometric method. The value obtained for p K a of N 2 -acetylacyclovir and previously reported p K a values (Kozjek et al., Acta Pharm. Jugosl., 38 (1988) 61–69; Kr
Publikováno v:
Drug Development and Industrial Pharmacy. 17:1109-1130
Ethylcelluloses of different types were used to microencapsulate bacampicillin. Polymer deposition from cyclohexane was performed by temperature change. As coacervation - inducing agent different polyisobutylenes (Oppanol B - 200, B - 100, B - 50, B
Publikováno v:
Scopus-Elsevier
Objective: The double-blind randomized pilot study was undertaken to compare the effects of a 10-day course of ondansetron 8 mg/day and propranolol 80 mg/day perorally in treating portal hypertension. Subjects and methods: 16 patients with liver dise
Publikováno v:
Biopharmaceuticsdrug disposition. 20(4)
Following a single oral administration of ciprofloxacin, norfloxacin, pefloxacin and ofloxacin preparations to healthy volunteers simultaneously collected, saliva and plasma 4-fluoroquinolone concentrations were assayed by HPLC. Pharmacokinetic prope
Publikováno v:
Journal of microencapsulation. 8(3)
Eudragit E microspheres containing bacampicillin hydrochloride were prepared by solvent evaporation and solvent extraction methods. Three different systems of solvents were used: methyl acetate, acetone and methanol/liquid paraffin. The success of th
Publikováno v:
European journal of drug metabolism and pharmacokinetics.
The relationships between physicochemical properties (ionization, solubility, partition, protein binding) of 4-quinolone derivatives and their pharmacokinetics was studied by means of in vitro methods. This information is needed to clarify the errati
Publikováno v:
European journal of drug metabolism and pharmacokinetics.
Urodynamic model was developed which, in conjunction with a compartmental pharmacokinetic model, was used for study of factors influencing drug concentrations in urine: urine flow rate, residual bladder urine, maximal bladder urine, stage of renal fa