Zobrazeno 1 - 10
of 674
pro vyhledávání: '"F. Kearney"'
Publikováno v:
Journal of Dairy Science, Vol 106, Iss 12, Pp 9778-9792 (2023)
ABSTRACT: The aims of this study were (1) to evaluate potential associations between genetic traits, postpartum phenotypes, cow factors, and postpartum vaginal discharge score (VDS); and (2) to investigate possible associations between postpartum VDS
Externí odkaz:
https://doaj.org/article/dc5bf2a653834e6593a7774e5948418a
Autor:
Hector Cordero, Rodney G. King, Pranay Dogra, Chloe Dufeu, Sarah B. See, Alexander M. Chong, Anne-Catrin Uhlemann, Siu-Hong Ho, David M. Kalfa, Emile A. Bacha, John F. Kearney, Emmanuel Zorn
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The thymus is known as the organ of T lymphocyte development. Here authors show that terminal B cell differentiation also takes place in the thymus of human neonates, leading to antibody production against commensal and pathogenic bacteria.
Externí odkaz:
https://doaj.org/article/e3974adc67504d398d0283ef6c71a113
Autor:
Imogen A. Wright, Michael J. Bale, Wei Shao, Wei-Shau Hu, John M. Coffin, Gert U. Van Zyl, Mary F. Kearney
Publikováno v:
Retrovirology, Vol 18, Iss 1, Pp 1-6 (2021)
Abstract The characterisation of the HIV-1 reservoir, which consists of replication-competent integrated proviruses that persist on antiretroviral therapy (ART), is made difficult by the rarity of intact proviruses relative to those that are defectiv
Externí odkaz:
https://doaj.org/article/f0403fb048314b8bad0786d7ae4c20b2
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Pancreatic ductal adenocarcinoma (PDAC) is notorious for a dense fibrotic stroma that is interlaced with a collagen-based extracellular matrix (ECM) that plays an important role in tumor biology. Traditionally thought to only provide a physical barri
Externí odkaz:
https://doaj.org/article/2e12b72ac7d0456381dd8495ea0e038d
Publikováno v:
Genetics Selection Evolution, Vol 51, Iss 1, Pp 1-11 (2019)
Abstract Background In modern dairy breeding programmes, high contributions from foreign sires are nearly always present. Genotyping, and therefore genomic selection (GS), concern only a subpopulation of the breeding programme’s wider dairy populat
Externí odkaz:
https://doaj.org/article/d42739f269f7480c9b0c7b988e8eb466
Autor:
John M Coffin, Michael J Bale, Daria Wells, Shuang Guo, Brian Luke, Jennifer M Zerbato, Michele D Sobolewski, Twan Sia, Wei Shao, Xiaolin Wu, Frank Maldarelli, Mary F Kearney, John W Mellors, Stephen H Hughes
Publikováno v:
PLoS Pathogens, Vol 17, Iss 4, p e1009141 (2021)
HIV persists during antiretroviral therapy (ART) as integrated proviruses in cells descended from a small fraction of the CD4+ T cells infected prior to the initiation of ART. To better understand what controls HIV persistence and the distribution of
Externí odkaz:
https://doaj.org/article/3e177632677e4f3b9ab7e952f1029063
Autor:
Michael J. Bale, Mary Grace Katusiime, Daria Wells, Xiaolin Wu, Jonathan Spindler, Elias K. Halvas, Joshua C. Cyktor, Ann Wiegand, Wei Shao, Mark F. Cotton, Stephen H. Hughes, John W. Mellors, John M. Coffin, Gert U. Van Zyl, Mary F. Kearney
Publikováno v:
mBio, Vol 12, Iss 2 (2021)
HIV-1 integrates its genome into the DNA of host cells. Consequently, HIV-1 genomes are copied with the host cell DNA during cellular division.
Externí odkaz:
https://doaj.org/article/24168db87d274281ba8cf37cddd5815b
Autor:
Yuta Hikichi, Rachel Van Duyne, Phuong Pham, Jennifer L. Groebner, Ann Wiegand, John W. Mellors, Mary F. Kearney, Eric O. Freed
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
Although combination antiretroviral (ARV) therapy is highly effective in controlling the progression of HIV disease, drug resistance can be a major obstacle. Recent findings suggest that resistance can develop without ARV target gene mutations.
Externí odkaz:
https://doaj.org/article/a4bd72fa01324caca28f6cbce9932f14
Publikováno v:
Viruses, Vol 14, Iss 1, p 104 (2022)
COVID-19 vaccines were first administered on 15 December 2020, marking an important transition point for the spread of SARS-CoV-2 in the United States (U.S.). Prior to this point in time, the virus spread to an almost completely immunologically naïv
Externí odkaz:
https://doaj.org/article/11d3d26fa43740f5a3e281f7522b0c9c
Autor:
Line Barington, Liv von Voss Christensen, Kristian Kåber Pedersen, Kristine Niss Arfelt, Martin Roumain, Kristian Høj Reveles Jensen, Viktoria Madeline Skovgaard Kjær, Viktorija Daugvilaite, John F. Kearney, Jan Pravsgaard Christensen, Gertrud Malene Hjortø, Giulio G. Muccioli, Peter Johannes Holst, Mette Marie Rosenkilde
Publikováno v:
Cells, Vol 11, Iss 3, p 494 (2022)
B1 cells constitute a specialized subset of B cells, best characterized in mice, which is abundant in body cavities, including the peritoneal cavity. Through natural and antigen-induced antibody production, B1 cells participate in the early defense a
Externí odkaz:
https://doaj.org/article/ecdf797f65d7414b8242f2c44e167d78