Zobrazeno 1 - 10
of 246
pro vyhledávání: '"F. Jenck"'
Autor:
R. Andreatini, C. Blanchard, R. Blanchard, M.L. Brandão, A.P. Carobrez, G. Griebel, F.S. Guimarães, S.L. Handley, F. Jenck, J.R. Leite, J. Rodgers, L.C. Schenberg, C. Da Cunha, F.G. Graeff
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 34, Iss 2, Pp 145-154 (2001)
This article is a transcription of an electronic symposium sponsored by the Brazilian Society of Neuroscience and Behavior (SBNeC). Invited researchers from the European Union, North America and Brazil discussed two issues on anxiety, namely whether
Externí odkaz:
https://doaj.org/article/9bac16a38fae456196ff4397fbd4e055
Autor:
F. Jenck, Jürgen Wichmann, James N.C. Kew, J. A. Kemp, J. G. Richards, Hiroshi Takeshima, Geo Adam, Guy A. Higgins, A. J. Grottick
Publikováno v:
European Journal of Neuroscience. 15:911-922
Using a combination of the selective opioid receptor-like 1 (ORL 1 ) receptor agonist, Ro 64-6198, and orphanin FQ/nociceptin (OFQ/N) peptide knockout (KO) mice, the influence of OFQ/N on cognition has been studied in therodent. In wild type, C57BL/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93fe9a5b1a6b6c5748cba2be0926c0fa
https://doi.org/10.1046/j.1460-9568.2002.01926.x
https://doi.org/10.1046/j.1460-9568.2002.01926.x
Publikováno v:
Journal of Receptors and Signal Transduction. 21:55-70
We have modified Semliki Forest virus (SFV) vectors to broaden their application range. Here we describe a series of site-directed mutagenesis experiments on the SFV subgenomic 26S promoter to down-regulate the heterologous gene expression. Several m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa8be325a2fabe661151e7baa507387b
https://doi.org/10.1081/rrs-100107142
https://doi.org/10.1081/rrs-100107142
Autor:
Jean F. Jenck
Publikováno v:
Microchemical Engineering in Practice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fc59dda781886924b945c4b38bd2667
https://doi.org/10.1002/9780470431870.ch1
https://doi.org/10.1002/9780470431870.ch1
Publikováno v:
European Journal of Pharmacology. 177:201-204
The selective serotonin (5-HT) uptake inhibitors fluvoxamine and sertraline had anti-aversive effects when administered acutely. Imipramine and clomipramine, which combine noradrenaline (NA) and 5-HT uptake blocking properties, did not have significa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb11f2414ff1b036c9e6b1af223b6ef3
https://doi.org/10.1016/0014-2999(90)90271-7
https://doi.org/10.1016/0014-2999(90)90271-7
Publikováno v:
Life sciences. 70(15)
Nociceptin/orphanin FQ (N/OFQ) is the endogenous ligand for the opioid receptor-like receptor or nociceptin receptor (NOP). We have compared a novel non-peptide NOP agonist Ro64-6198 with N/OFQ in a series of GTPgamma35S binding and inhibition of for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c299322ba6e8e01e4c579458178a371
https://pubmed.ncbi.nlm.nih.gov/12002517
https://pubmed.ncbi.nlm.nih.gov/12002517
Autor:
G A, Higgins, J N C, Kew, J G, Richards, H, Takeshima, F, Jenck, G, Adam, J, Wichmann, J A, Kemp, A J, Grottick
Publikováno v:
The European journal of neuroscience. 15(5)
Using a combination of the selective opioid receptor-like1 (ORL1) receptor agonist, Ro 64-6198, and orphanin FQ/nociceptin (OFQ/N) peptide knockout (KO) mice, the influence of OFQ/N on cognition has been studied in the rodent. In wild type, C57BL/6J
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::247c8faaf5031d5c370893fc7418258e
https://pubmed.ncbi.nlm.nih.gov/11906533
https://pubmed.ncbi.nlm.nih.gov/11906533
Autor:
F M, Dautzenberg, J, Wichmann, J, Higelin, G, Py-Lang, C, Kratzeisen, P, Malherbe, G J, Kilpatrick, F, Jenck
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 298(2)
The novel nonpeptide orphanin FQ/nociceptin (OFQ/N) ligand [(1S,3aS)-8-(2,3,3a,4,5,6-hexahydro-1H-phenalen-1-yl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one] (Ro 64-6198) was characterized in vitro and in vivo for its agonistic potential. Ro 64-6198
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::960072fd8c89085166ebaa4e0d119980
https://pubmed.ncbi.nlm.nih.gov/11454946
https://pubmed.ncbi.nlm.nih.gov/11454946
Publikováno v:
Journal of psychopharmacology (Oxford, England). 13(2)
Acute systemic administration of the selective serotonin (5-HT)1A receptor full agonist flesinoxan enhanced the sensitivity of rats to the panic-like aversion elicited by local stimulation of the dorsolateral periaqueductal grey (dPAG). This experime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::53bb15f41c19edec5660db5cca32fc2a
https://pubmed.ncbi.nlm.nih.gov/10475723
https://pubmed.ncbi.nlm.nih.gov/10475723
Autor:
J R, Martin, M, Bös, F, Jenck, J, Moreau, V, Mutel, A J, Sleight, J, Wichmann, J S, Andrews, H H, Berendsen, C L, Broekkamp, G S, Ruigt, C, Köhler, A M, Delft
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 286(2)
In vitro, (S)-2-(chloro-5-fluoro-indol-1-yl)-1-methylethylamine 1:1 C4H4O4 and (S)-2-(4,4,7-trimethyl-1,4-dihydro-indeno[1, 2-b]pyrrol-1-yl)-1-methylethylamine 1:1 C4H4O4 exhibited high-affinity binding to the serotonin2C (5HT2C) receptors and stimul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db31178198fb996d4e77a717706b8b69
https://pubmed.ncbi.nlm.nih.gov/9694950
https://pubmed.ncbi.nlm.nih.gov/9694950