Zobrazeno 1 - 10
of 53
pro vyhledávání: '"F. Jeffrey Field"'
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 6, Pp 1407-1415 (2010)
HDL cholesterol levels are decreased in Crohn's disease, a tumor necrosis factor-α (TNF-α)–driven chronic inflammatory condition involving the gastrointestinal tract. ATP-binding cassette transporter A1 (ABCA1), one of several liver X receptor (L
Externí odkaz:
https://doaj.org/article/d1c0417a65164beaa366b462351beb53
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 12, Pp 2605-2619 (2008)
The origins of cholesterol utilized by intestinal ABCA1 were investigated in the human intestinal cell line Caco-2. Influx of apical membrane cholesterol increases ABCA1 mRNA and mass, resulting in enhanced efflux of HDL-cholesterol. Luminal (micella
Externí odkaz:
https://doaj.org/article/577cb3d7fc2246b18102c557992cedf0
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 8, Pp 1735-1745 (2007)
Niemann-Pick C1-like 1 protein (NPC1L1) is the putative intestinal sterol transporter and the molecular target of ezetimibe, a potent inhibitor of cholesterol absorption. To address the role of NPC1L1 in cholesterol trafficking in intestine, the regu
Externí odkaz:
https://doaj.org/article/d6d0fa1ec477464eabedd1b730f5bbe8
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 2, Pp 395-404 (2007)
To address the effect of the n-3 fatty acid, docosahexaenoic acid (22:6), on proteins that play a role in cholesterol absorption, CaCo-2 cells were incubated with taurocholate micelles alone or micelles containing 22:6 or oleic acid (18:1). Compared
Externí odkaz:
https://doaj.org/article/533c072d6b594a39a07dd941a388b758
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 12, Pp 2252-2259 (2004)
Possible mechanisms for the cholesterol-lowering effects of plant stanol esters were addressed by feeding hamsters diets containing stanol esters, cholesterol, or cholestyramine/lovastatin. ABCA1, ATP binding cassette G1 (ABCG1), ABCG5, ABCG8, and Ni
Externí odkaz:
https://doaj.org/article/e91854df81c040b19b612aaeed145850
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 5, Pp 905-913 (2004)
To examine whether intestinal ABCA1 was responsible for the differences observed between cholesterol and β-sitosterol absorption, ABCA1-facilitated β-sitosterol efflux was investigated in CaCo-2 cells following liver X receptor/retinoid X receptor
Externí odkaz:
https://doaj.org/article/2a35342707544eceb803e513f080427a
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 6, Pp 1199-1208 (2003)
Hamsters were fed a control diet or diets containing palm, olive, safflower, or fish oil for 2 weeks. In villus cell populations from duodenum, jejunum, and ileum, rates of intestinal fatty acid and cholesterol synthesis were estimated, as were stero
Externí odkaz:
https://doaj.org/article/f1910ee21d9348b6912907fe1f70491c
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 7, Pp 1054-1064 (2002)
Regulation of gene expression of ATP-binding cassette transporter (ABC)A1 and ABCG1 by liver X receptor/retinoid X receptor (LXR/RXR) ligands was investigated in the human intestinal cell line CaCo-2. Neither the RXR ligand, 9-cis retinoic acid, nor
Externí odkaz:
https://doaj.org/article/a05eeac4ce554d6b9a3d1e2445814f5c
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 10, Pp 1687-1698 (2001)
The regulation of sterol regulatory element-binding proteins (SREBP) by cholesterol flux was studied in the intestinal cell line CaCo-2. CaCo-2 cells were incubated for 18 h with micelles containing 5 mM taurocholate and 500 μM oleic acid or micelle
Externí odkaz:
https://doaj.org/article/e360fe438b5845c993ccc4925b95c397
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 1, Pp 1-8 (2001)
Gene expression of sterol regulatory element-binding proteins 1a, 1c, and 2 (SREBP-1a, -1c, and -2) and of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) synthase, HMG-CoA reductase, and the low density lipoprotein (LDL) receptor was examined in ham
Externí odkaz:
https://doaj.org/article/158dc626238d4d159ec318dd0593d070