Zobrazeno 1 - 10
of 86
pro vyhledávání: '"F. Jeffrey Dilworth"'
Autor:
Matthieu Dos Santos, Stéphanie Backer, Frédéric Auradé, Matthew Man-Kin Wong, Maud Wurmser, Rémi Pierre, Francina Langa, Marcio Do Cruzeiro, Alain Schmitt, Jean-Paul Concordet, Athanassia Sotiropoulos, F. Jeffrey Dilworth, Daan Noordermeer, Frédéric Relaix, Iori Sakakibara, Pascal Maire
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The contractile properties of adult myofibers are shaped by their Myosin heavy chain isoform content. Here the authors show that a super enhancer controls the spatiotemporal expression of the genes at the fast myosin heavy chain locus by DNA looping
Externí odkaz:
https://doaj.org/article/1e1732b409944febbd7c8c1cfe87a24b
Autor:
Joana Esteves de Lima, Reem Bou Akar, Léo Machado, Yuefeng Li, Bernadette Drayton-Libotte, F. Jeffrey Dilworth, Frédéric Relaix
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
The epigenetic mechanisms coordinating the maintenance of adult cellular lineages remain poorly understood. Here the authors demonstrate that HIRA, a H3.3 histone chaperone, establishes the chromatin landscape required for skeletal muscle cell identi
Externí odkaz:
https://doaj.org/article/131bbfcf00ff49249c28bd0b0b877a5f
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Cartilage injury and degeneration are hallmarks of osteoarthritis (OA), the most common joint disease. OA is a major contributor to pain, loss of function, and reduced quality of life. Over the last decade, considerable research efforts have focused
Externí odkaz:
https://doaj.org/article/25c2af8485ed459b889f9fe6acc16287
Publikováno v:
Skeletal Muscle, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract In response to muscle injury, muscle stem cells integrate environmental cues in the damaged tissue to mediate regeneration. These environmental cues are tightly regulated to ensure expansion of muscle stem cell population to repair the damag
Externí odkaz:
https://doaj.org/article/3e367a677de84733be4fb87e21a25218
Autor:
Yuefeng Li, Kiran Nakka, Thomas Olender, Philippe Gingras-Gelinas, Matthew Man-Kin Wong, Daniel C.L. Robinson, Hina Bandukwala, Carmen G. Palii, Odile Neyret, Marjorie Brand, Alexandre Blais, F. Jeffrey Dilworth
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100751- (2021)
Summary: Muscle stem cells (MuSCs) are a rare stem cell population that provides myofibers with a remarkable capacity to regenerate after tissue injury. Here, we have adapted the Cleavage Under Target and Tagmentation technology to the mapping of the
Externí odkaz:
https://doaj.org/article/f989f7be26944ccc96e78c9e1194ad76
Autor:
Ryan A. V. Bell, Mohammad H. Al-Khalaf, Steve Brunette, Dalal Alsowaida, Alphonse Chu, Hina Bandukwala, Georg Dechant, Galina Apostolova, F. Jeffrey Dilworth, Lynn A. Megeney
Publikováno v:
Cells, Vol 11, Iss 6, p 966 (2022)
The induction of lineage-specific gene programs are strongly influenced by alterations in local chromatin architecture. However, key players that impact this genome reorganization remain largely unknown. Here, we report that the removal of the specia
Externí odkaz:
https://doaj.org/article/401e503390fc466fa68ff97a37303090
Publikováno v:
Skeletal Muscle, Vol 8, Iss 1, Pp 1-18 (2018)
Abstract Background Skeletal muscles express a highly specialized proteome that allows the metabolism of energy sources to mediate myofiber contraction. This muscle-specific proteome is partially derived through the muscle-specific transcription of a
Externí odkaz:
https://doaj.org/article/f4079098154b42908404cb0bf5244e48
Autor:
Jimmy Massenet, Michèle Weiss-Gayet, Hina Bandukwala, Mélanie Magnan, Arnaud Hubas, Patrick Nusbaum, Isabelle Desguerre, Cyril Gitiaux, F Jeffrey Dilworth, Bénédicte Chazaud
In Duchenne Muscular Dystrophy (DMD), the absence of the subsarcolemmal dystrophin protein leads to repeated myofiber damages inducing cycles of muscle regeneration that is driven by muscle stem cells (MuSCs). With time, MuSC regenerative capacities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dda4d2f741d4dfd11476ea202ba1541
https://doi.org/10.1101/2023.04.26.538414
https://doi.org/10.1101/2023.04.26.538414
Autor:
William L. Stanford, Caryn Y. Ito, Mitchell Sabloff, Theodore J. Perkins, F. Jeffrey Dilworth, Alexander J. Ruthenburg, Elham Sabri, Adrian T. Grzybowski, Yuefeng Li, Joel P. Howard, Safwat T. Khan, Hannah L. Battaion, Julien Yockell-Lelièvre, Christopher J. Porter, Janet L. Manias Rothberg, Christopher Cafariello, Hani Jrade, Harinad B. Maganti
Supplementary figures and legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::768a48405a5ec3f531527029e18918fb
https://doi.org/10.1158/2159-8290.22531762.v1
https://doi.org/10.1158/2159-8290.22531762.v1
Autor:
William L. Stanford, Caryn Y. Ito, Mitchell Sabloff, Theodore J. Perkins, F. Jeffrey Dilworth, Alexander J. Ruthenburg, Elham Sabri, Adrian T. Grzybowski, Yuefeng Li, Joel P. Howard, Safwat T. Khan, Hannah L. Battaion, Julien Yockell-Lelièvre, Christopher J. Porter, Janet L. Manias Rothberg, Christopher Cafariello, Hani Jrade, Harinad B. Maganti
Extended Material and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac72e4f80651b083344b03a2662fac9b
https://doi.org/10.1158/2159-8290.22531774
https://doi.org/10.1158/2159-8290.22531774