Zobrazeno 1 - 10
of 193
pro vyhledávání: '"F. Javier Cañada"'
Publikováno v:
ACS Omega, Vol 5, Iss 49, Pp 31821-31830 (2020)
Externí odkaz:
https://doaj.org/article/f7e183f0a7a04341a53e20489ef14e58
Autor:
Ana Serrano, Eva Calviño, Juan Carro, María I. Sánchez-Ruiz, F. Javier Cañada, Angel T. Martínez
Publikováno v:
Biotechnology for Biofuels, Vol 12, Iss 1, Pp 1-12 (2019)
Abstract Background 5-Hydroxymethylfurfural (HMF) is a highly valuable platform chemical that can be obtained from plant biomass carbohydrates. HMF can be oxidized to 2,5-furandicarboxylic acid (FDCA), which is used as a renewable substitute for the
Externí odkaz:
https://doaj.org/article/36c2ae0df29e47cb800bf139eac52e78
Autor:
Andrea Canal-Martín, Javier Sastre, María José Sánchez-Barrena, Angeles Canales, Sara Baldominos, Naiara Pascual, Loreto Martínez-González, Dolores Molero, Mª Encarnación Fernández-Valle, Elena Sáez, Patricia Blanco-Gabella, Elena Gómez-Rubio, Sonsoles Martín-Santamaría, Almudena Sáiz, Alicia Mansilla, F. Javier Cañada, Jesús Jiménez-Barbero, Ana Martínez, Ruth Pérez-Fernández
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Dynamic combinatorial chemistry (DCC) is instrumental in the discovery of ligands for pharmaceutical targets. Here, the authors adapted DCC to work at 4 degrees Celsius and used it to identify a ligand for Neuronal Calcium Sensor-1 that promotes NCS-
Externí odkaz:
https://doaj.org/article/851d08b0cab545c2b42eefe2157d74fa
Autor:
Jon I. Quintana, Sandra Delgado, Reyes Núñez-Franco, F. Javier Cañada, Gonzalo Jiménez-Osés, Jesús Jiménez-Barbero, Ana Ardá
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
The tandem-repeat Galectin-4 (Gal-4) contains two different domains covalently linked through a short flexible peptide. Both domains have been shown to bind preferentially to A and B histo blood group antigens with different affinities, although the
Externí odkaz:
https://doaj.org/article/21991250808a4ed0add6d09e050c0ee5
Autor:
María A. Pajares, Tahl Zimmerman, Francisco J. Sánchez-Gómez, Adriana Ariza, María J. Torres, Miguel Blanca, F. Javier Cañada, María I. Montañez, Dolores Pérez-Sala
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Serum and cellular proteins are targets for the formation of adducts with the β-lactam antibiotic amoxicillin. This process could be important for the development of adverse, and in particular, allergic reactions to this antibiotic. In studies explo
Externí odkaz:
https://doaj.org/article/3ce8a42f59d342d7b2d586d943532fce
Autor:
J. Andrés Valderrama, Helena Gómez-Álvarez, Zaira Martín-Moldes, M. Álvaro Berbís, F. Javier Cañada, Gonzalo Durante-Rodríguez, Eduardo Díaz
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT We have identified and characterized the AccS multidomain sensor kinase that mediates the activation of the AccR master regulator involved in carbon catabolite repression (CCR) of the anaerobic catabolism of aromatic compounds in Azoarcus sp
Externí odkaz:
https://doaj.org/article/30e0602224694fca96311536bc542b48
Autor:
J. Daniel Martínez, Pablo Valverde, Sandra Delgado, Cecilia Romanò, Bruno Linclau, Niels C. Reichardt, Stefan Oscarson, Ana Ardá, Jesús Jiménez-Barbero, F. Javier Cañada
Publikováno v:
Molecules, Vol 24, Iss 12, p 2337 (2019)
A fluorine nuclear magnetic resonance (19F-NMR)-based method is employed to assess the binding preferences and interaction details of a library of synthetic fluorinated monosaccharides towards dendritic cell-specific intercellular adhesion molecule 3
Externí odkaz:
https://doaj.org/article/36fc43d916b04b25b8609f9786b84013
Publikováno v:
ACS Omega, Vol 5, Iss 49, Pp 31821-31830 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
instname
ACS Omega
Digital.CSIC. Repositorio Institucional del CSIC
instname
ACS Omega
10 p.-2 fig.-3 schem.-1 chart
Synthesis of four iminosugars fused to a cyclopropane ring is described using l-serine as the chiral pool. The key steps are large-scale preparation of an alpha,beta-unsaturated piperidinone followed by completely s
Synthesis of four iminosugars fused to a cyclopropane ring is described using l-serine as the chiral pool. The key steps are large-scale preparation of an alpha,beta-unsaturated piperidinone followed by completely s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db554fc18920ded6944365b5b7e49373
https://doaj.org/article/f7e183f0a7a04341a53e20489ef14e58
https://doaj.org/article/f7e183f0a7a04341a53e20489ef14e58
Autor:
F. Javier Cañada, Ángel T. Martínez, Ana Serrano, María Isabel Sánchez-Ruiz, Eva Calviño, Juan Carro
Publikováno v:
Biotechnology for Biofuels, Vol 12, Iss 1, Pp 1-12 (2019)
Biotechnology for Biofuels
Digital.CSIC. Repositorio Institucional del CSIC
instname
Biotechnology for Biofuels
Digital.CSIC. Repositorio Institucional del CSIC
instname
[Background] 5-Hydroxymethylfurfural (HMF) is a highly valuable platform chemical that can be obtained from plant biomass carbohydrates. HMF can be oxidized to 2,5-furandicarboxylic acid (FDCA), which is used as a renewable substitute for the petrole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ca01c6704e5aaf117457594b230ddb3
http://link.springer.com/article/10.1186/s13068-019-1555-z
http://link.springer.com/article/10.1186/s13068-019-1555-z
Autor:
Jesús Jiménez-Barbero, María José Sánchez-Barrena, F. Javier Cañada, Elena Gómez-Rubio, Almudena Sáiz, Patricia Blanco-Gabella, Elena Sáez, Sara Baldominos, Naiara Pascual, Alicia Mansilla, Javier Sastre, Ángeles Canales, Dolores Molero, Sonsoles Martín-Santamaría, Loreto Martínez-González, Ana Martínez, Ruth Pérez-Fernández, Mª Encarnación Fernández-Valle, Andrea Canal-Martín
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
13 p.-9 fig.-1 tab.
Dynamic combinatorial chemistry (DCC) has proven its potential in drug discovery speedingthe identification of modulators of biological targets. However, the exchange chemistriestypically take place under specific reaction co
Dynamic combinatorial chemistry (DCC) has proven its potential in drug discovery speedingthe identification of modulators of biological targets. However, the exchange chemistriestypically take place under specific reaction co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c7679ce5725584876f93eee9255e5b0
http://link.springer.com/article/10.1038/s41467-019-10627-w
http://link.springer.com/article/10.1038/s41467-019-10627-w