Zobrazeno 1 - 10
of 20
pro vyhledávání: '"F. Jason Duncan"'
Autor:
Adriana N. Schmidt, John P. Sundberg, Lloyd E. King, Susan R. Opalenik, F. Jason Duncan, Helen B. Everts, Kathleen A. Silva, David E. Ong
Publikováno v:
Nutr Res
Topical 17-beta-estradiol (E2) regulates the hair cycle, hair shaft differentiation, and sebum production. Vitamin A also regulates sebum production. Vitamin A metabolism proteins localized to the pilosebaceous unit (PSU; hair follicle and sebaceous
Autor:
Bartholomew J Naughton, F Jason Duncan, Darren Murrey, Tierra Ware, Aaron Meadows, Douglas M McCarty, Haiyan Fu
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80142 (2013)
Mucopolysaccharidosis (MPS) IIIB is a devastating neuropathic lysosomal storage disease with complex pathology. This study identifies molecular signatures in peripheral blood that may be relevant to MPS IIIB pathogenesis using a mouse model. Genome-w
Externí odkaz:
https://doaj.org/article/1765de5a86994bc2a248fcd3df484760
Autor:
Douglas M. McCarty, Christopher Shilling, Brad Bolon, William G. Bremer, Christopher M. Walker, Kimberly Zaraspe, Aaron S. Meadows, Chrystal L. Montgomery, Haiyan Fu, Kevin M. Flanigan, F. Jason Duncan, Kathryn Waligura, Marybeth Camboni, Bartholomew J. Naughton, Kim L. McBride
Publikováno v:
Human Gene Therapy Clinical Development. 26:228-242
No treatment is currently available for mucopolysaccharidosis (MPS) IIIB, a neuropathic lysosomal storage disease due to defect in α-N-acetylglucosaminidase (NAGLU). In preparation for a clinical trial, we performed an IND-enabling GLP-toxicology st
Autor:
Katie Campbell, Haiyan Fu, Darren A. Murrey, Bartholomew J. Naughton, Brad Bolon, Christopher M. Walker, Tierra Ware, Douglas M. McCarty, F. Jason Duncan, Krista M. D. La Perle, Kevin M. Flanigan, Kim L. McBride, William G. Bremer, Laurie Goodchild, Aaron S. Meadows
Publikováno v:
Human Gene Therapy Clinical Development. 25:72-84
No treatment is currently available for mucopolysaccharidosis (MPS) IIIB, a neuropathic lysosomal storage disease caused by autosomal recessive defect in α-N-acetylglucosaminidase (NAGLU). In anticipation of a clinical gene therapy treatment for MPS
Autor:
Helen B. Everts, Kathleen A. Silva, David E. Ong, Charles J. Johnson, John P. Sundberg, Joseph L. Napoli, Jinshan Wang, Benjamin L. King, Kevin J. McElwee, David A. Whiting, Sonya P. Kamdar, Jin P. Szatkiewicz, Lloyd E. King, F. Jason Duncan
Publikováno v:
The Journal of investigative dermatology
Alopecia areata (AA) is an autoimmune disease that attacks anagen hair follicles. Gene array in graft-induced C3H/HeJ mice revealed that genes involved in retinoic acid (RA) synthesis were increased, whereas RA degradation genes were decreased in AA
Autor:
Lianbo Yu, Amanda E. Toland, Anne M. VanBuskirk, Amy M. Dworkin, Kathleen L. Tober, F. Jason Duncan, Tatiana M. Oberyszyn
Publikováno v:
Genes, Chromosomes and Cancer. 48:490-501
In immunocompromised individuals, such as organ transplant recipients, the risk of cutaneous squamous cell carcinoma (SCC) is increased 60-250 fold, and there is an increased likelihood to develop aggressive, metastatic SCC. An understanding of the g
Autor:
Kimberly M. Newkirk, F. Jason Duncan, Donna F. Kusewitt, Erin M. Brannick, Allison E. Parent, Heather L. Chandler
Publikováno v:
Laboratory Investigation. 88:831-841
We previously reported ultraviolet radiation (UVR) induction of Slug, a Snail family zinc-finger transcription factor, in the epidermis of mice; we now report that Slug-knockout mice are, unexpectedly, more resistant to sunburn than wild-type mice. T
Autor:
Chrystal Mongomery, F. Jason Duncan, Brad Bolon, Christopher M. Walker, Marybeth Camboni, Kevin M. Flanigan, William G. Bremer, Haiyan Fu, Kathryn Waligura, Aaron S. Meadows, Douglas M. McCarty, Kim L. McBride
Publikováno v:
Molecular Therapy. 23
No treatment is currently available for mucopolysaccharidosis (MPS) IIIB, a neuropathic lysosomal storage disease due to autosomal recessive defect in α-N-acetylglucosaminidase (NAGLU). In preparation for a clinical trial, we performed an IND-enabli
Autor:
Krista M. D. La Perle, Helen B. Everts, Tatiana M. Oberyszyn, Katherine Lynne Gressel, F. Jason Duncan
Ultraviolet light B (UVB) exposure induces cutaneous squamous cell carcinoma (cSCC), one of the most prevalent human cancers. Reoccurrence of cSCC in high-risk patients is prevented by oral retinoids. But oral retinoid treatment causes significant si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdbe069600df6eea6b44426b065332bb
https://europepmc.org/articles/PMC4509636/
https://europepmc.org/articles/PMC4509636/
Autor:
Bridget L. Colvin, Angus W. Thomson, F. Jason Duncan, P. Toby H. Coates, Alan F. Zahorchak, Adrian E. Morelli, Zhiliang Wang, William J. Shufesky
Publikováno v:
Transplantation. 77:1080-1089
Background. Migratory antigen-presenting cells resident in kidneys may have tolerogenic potential. Difficulties inherent in their isolation have limited their characterization. The authors examined the phenotype and function of murine kidney dendriti