Zobrazeno 1 - 10
of 41
pro vyhledávání: '"F. Jacob Huff"'
Autor:
Kenneth C. Cundy, Katie Zomorodi, Dmitri Lissin, Peter A. LeWitt, F. Jacob Huff, Dan Chen, Robert A. Hauser
Publikováno v:
Movement Disorders. 29:75-82
The objective of this study was to assess the efficacy, safety, and pharmacokinetics of XP21279-carbidopa in patients with Parkinson's disease who experience motor fluctuations compared with immediate-release carbidopa-levodopa tablets. XP21279 is a
Autor:
Peter A, LeWitt, F Jacob, Huff, Robert A, Hauser, Dan, Chen, Dmitri, Lissin, Katie, Zomorodi, Kenneth C, Cundy
Publikováno v:
Movement disorders : official journal of the Movement Disorder Society. 29(1)
The objective of this study was to assess the efficacy, safety, and pharmacokinetics of XP21279-carbidopa in patients with Parkinson's disease who experience motor fluctuations compared with immediate-release carbidopa-levodopa tablets. XP21279 is a
Autor:
Katie Zomorodi, Dan Chen, Wendy Luo, Kristin McGuire, F. Jacob Huff, Ritu Lal, Aaron Ellenbogen, Peter A LeWitt
Publikováno v:
Clinical neuropharmacology. 35(3)
OBJECTIVE The objectives of this study were to assess the pharmacokinetic profile, efficacy, and safety of XP21279 administered with carbidopa (CD) in subjects with Parkinson disease (PD) experiencing motor fluctuations and explore dose correspondenc
Publikováno v:
The American journal of gastroenterology. 106(8)
It has been shown that arbaclofen placarbil (AP) inhibits reflux in gastroesophageal reflux disease (GERD) following single oral dosing. This study evaluated the efficacy and safety of AP over 4 weeks in subjects with symptomatic GERD.One hundred fif
Publikováno v:
Clinical Neuropsychologist. 7:313-318
The Mattis Dementia Rating Scale (MDRS) is widely used to evaluate cognitive function in older adults who may be suffering from dementing illnesses. This report describes a factor analytic approach taken to investigate the constructs underlying the p
Autor:
William K. Hirota, Lauren B. Gerson, Wendy Luo, Amit Agrawal, Ritu Lal, Sandra F. Reilley, Amine Hila, F. Jacob Huff, Donald O. Castell
Publikováno v:
The American journal of gastroenterology. 105(6)
Arbaclofen placarbil (AP), previously designated as XP19986, is an investigational prodrug of the active R-isomer of baclofen, a gamma-aminobutyric acid agonist reflux inhibitor. The aim of this study was to assess the efficacy and safety of AP for d
Autor:
Stephen T. Hardiman, Ursula E. Knappe, Craig Dobson, John J. Demkovich, Michael F. Murphy, F. Jacob Huff, Ralph J. Nash
Publikováno v:
Annals of the New York Academy of Sciences. 640:253-262
HP 029 (1,2,3,4-tetrahydro-9-aminoacridin-1-ol-maleate) is a cholinesterase inhibitor and one of a series of compounds synthesized at Hoechst-Roussel Pharmaceuticals Inc. (HRPI) as a potential therapeutic agent for senile dementia of the Alzheimer ty
Publikováno v:
Dementia and Geriatric Cognitive Disorders. 1:32-40
The prevalence of abnormal neurologic symptoms and signs in mildly to moderately demented patients with Alzheimer''s disease (AD) was determined by comparison with healthy control subjects, and abnormal findings in AD were examined in relation to pro
Autor:
Barbara Jacobs, Trey Sunderland, J. Scott Stiffler, George S. Zubenko, Hugh B. Hughes, Ethel Winwood, Ivana Teply, F. Jacob Huff, A. Julio Martinez
Publikováno v:
The American journal of psychiatry. 156(1)
The primary goal of this study was to evaluate increased platelet membrane fluidity as a putative risk factor for Alzheimer's disease and its relationship to the APOE epsilon4 genotype.This report describes the results of a prospective, longitudinal
Publikováno v:
Gastroenterology. 142:S-210