Zobrazeno 1 - 8
of 8
pro vyhledávání: '"F. J. Meloni"'
Autor:
Barbara A. Konkle, K Huebner, M D Kelly, T Druck, F J Meloni, Sandor S. Shapiro, David W. Essex
Publikováno v:
Journal of Clinical Investigation. 93:2417-2424
Glycoprotein Ib beta (GPIb beta) exists in platelets disulfide-linked to glycoprotein Ib alpha (GPIb alpha), a major receptor for von Willebrand factor. Both GPIb alpha and GPIb beta are expressed in endothelial cells (EC). While the GPIb alpha mRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b305ba5b979e09015ffd79b6e3e02047
https://doi.org/10.1172/jci117249
https://doi.org/10.1172/jci117249
Publikováno v:
Thrombosis Research. 67:479-489
Recent studies from our laboratory indicate that purified kininogens are noncompetitive inhibitors of human alpha-thrombin but not PPACK-thrombin, binding to human washed platelets. In order to understand the mechanism by which the kininogens inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48c95229b96e6d0977f3e31c23ba65bd
https://doi.org/10.1016/0049-3848(92)90010-8
https://doi.org/10.1016/0049-3848(92)90010-8
Publikováno v:
Blood. 79:1233-1244
The unstimulated platelet surface contains a specific and saturable binding site for high molecular weight kininogen (HK) and low molecular weight kininogen (LK). Investigations were performed with purified heavy and light chains of HK to determine w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6ef03f95b5289cb6bebbcd79b1009c
https://doi.org/10.1182/blood.v79.5.1233.bloodjournal7951233
https://doi.org/10.1182/blood.v79.5.1233.bloodjournal7951233
Publikováno v:
Blood. 90(7)
The platelet glycoprotein Ib (GpIb) complex is composed of four polypeptides: the disulfide-linked GpIb alpha and GpIb beta and the noncovalently associated GpIX and GpV. GpIb alpha contains binding sites for von Willebrand factor and for thrombin an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::835310e927aea32270bff0af1f3d5575
https://pubmed.ncbi.nlm.nih.gov/9326233
https://pubmed.ncbi.nlm.nih.gov/9326233
Publikováno v:
Blood. 87(7)
The platelet membrane glycoprotein (Gp) Ib complex consists of four polypeptides: the disulfide-linked GpIb alpha and GpIb beta subunits; GpIX, tightly, but noncovalently associated with GpIb alpha-beta; and the more weakly associated GpV. It is not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4b5ed1d005c21520121f2d75e3c12f8e
https://pubmed.ncbi.nlm.nih.gov/8639895
https://pubmed.ncbi.nlm.nih.gov/8639895
Publikováno v:
Thrombosis and haemostasis. 68(2)
Purified domains of low molecular weight kininogen (LK) can be used directly to determine the epitopes of monoclonal antibodies (mAbs) that have been shown to influence kininogen function. LK, purified from plasma by carboxymethyl-papain-Sepharose 4B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c6c0d95764caad7aea3a166a0369be4
https://pubmed.ncbi.nlm.nih.gov/1412158
https://pubmed.ncbi.nlm.nih.gov/1412158
Autor:
F J, Meloni, A H, Schmaier
Publikováno v:
The Journal of biological chemistry. 266(11)
The kininogens, high molecular weight kininogen (HK) and low molecular weight kininogen (LK), are multifunctional, single-gene products that contain bradykinin and identical amino-terminal heavy chains. Studies were performed to determine if LK would
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de42368a2abc822b1b2a8214b3e26ad0
https://pubmed.ncbi.nlm.nih.gov/2016293
https://pubmed.ncbi.nlm.nih.gov/2016293
Publikováno v:
The Journal of laboratory and clinical medicine. 115(1)
Hereditary angioedema (HAE), an autosomal disorder caused by a deficiency of C1 inhibitor, is characterized by attacks of localized swelling, laryngeal edema, or abdominal pain. Plasma samples from one pregnant patient were studied serially by functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e5724b18a55113dbd2a709d3e218bdcd
https://pubmed.ncbi.nlm.nih.gov/1688910
https://pubmed.ncbi.nlm.nih.gov/1688910