Zobrazeno 1 - 10
of 10
pro vyhledávání: '"F. J. Kniffen"'
Autor:
J. K. Gibson, V. V. Ranade, M. Mimnaugh, T. Yu, N. J. Korn, F. J. Kniffen, Benedict R. Lucchesi, R. E. Counsell
Publikováno v:
Journal of Pharmaceutical Sciences. 69:1010-1013
Iodinated and radioiodinated analogs of propranolol and N,N-dimethylpropranolol were synthesized wherein an iodophenyl moiety replaced the naphthalene ring of the parent drug. These new compounds were evaluated not only for their β-adrenergic blocki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a23437dea3c450236669bed15fde534
https://doi.org/10.1002/jps.2600690907
https://doi.org/10.1002/jps.2600690907
Publikováno v:
European Journal of Pharmacology. 18:107-115
The effects of glucagon-low insulin were studied on canine isolated papillary muscles incubated in Chenoweth-Kolle solution and in the pentobarbital anesthetized dog. Insulin, 12.5 mU/ml, increased developed isometric tension of papillary muscles whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1878b334c24a3f4ea98eed081baf488b
https://doi.org/10.1016/0014-2999(72)90137-9
https://doi.org/10.1016/0014-2999(72)90137-9
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 192(1)
The antiarrhythmic, adrenergic-stimulating and blocking properties of bretylium and a structural analog UM-360, o-iodobenzyl trimethylammonium chloride, were studied in the anesthetized dog. Bretylium produced an initial sympathomimetic effect with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::42401d6d9d1d248e5bb4734b136ea290
https://pubmed.ncbi.nlm.nih.gov/1123718
https://pubmed.ncbi.nlm.nih.gov/1123718
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 196(2)
The quarternary ammonium compound, UM-424 [1-dimethyl isopropylamino-3-(2-phenylphenoxy)-propan-2-ol chloride], was evaluated for its antiarrhythmic and hemodynamic effects. UM-424 converted ouabain-induced ventricular tachycardia in the anesthetized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7ae11af20803185120e83d3ce4fb4ed7
https://pubmed.ncbi.nlm.nih.gov/3643
https://pubmed.ncbi.nlm.nih.gov/3643
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 194(1)
The effect of dimethyl quarternary propranolol, UM-272, on myocardial oxygen consumption was determined experimentally in anesthetized, open-chest dogs in which the left anterior descending and circumflex coronary arteries were cannulated and perfuse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3302b8ec1d85f7624784e8340c596b68
https://pubmed.ncbi.nlm.nih.gov/1151752
https://pubmed.ncbi.nlm.nih.gov/1151752
Autor:
B R, Lucchesi, F J, Kniffen
Publikováno v:
Circulation. 52
The adrenergic neurohumors, when present locally in the myocardium in high concentrations, can produce a variety of cardiac arrhythmias which may develop into ventricular fibrillation (VF). Of particular importance are the arrhythmias observed immedi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3d118e343be6ebffda23bf6df414b918
https://pubmed.ncbi.nlm.nih.gov/1182977
https://pubmed.ncbi.nlm.nih.gov/1182977
The comparative antiarrhythmic actions of lidocaine and its quarternary derivative, methyl lidocaine
Publikováno v:
Circulation. 49(2)
Lidocaine has proved to be an effective antiarrhythmic agent in the management of ventricular arrhythmias subsequent to acute myocardial infarction. Lidocaine's short duration of action and its propensity for producing central nervous system (CNS) st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ab2c4fcb8b7bafee9f991cb41c77488
https://pubmed.ncbi.nlm.nih.gov/4810558
https://pubmed.ncbi.nlm.nih.gov/4810558
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 184(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2a9fac1516014bfee0917651f4015786
https://pubmed.ncbi.nlm.nih.gov/4405548
https://pubmed.ncbi.nlm.nih.gov/4405548
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 187(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d507a8ef520384bfc3d2e66f9a42a425
https://pubmed.ncbi.nlm.nih.gov/4356014
https://pubmed.ncbi.nlm.nih.gov/4356014
Autor:
F. J. Kniffen, Benedict R. Lucchesi
Publikováno v:
The American Journal of Cardiology. 31:142
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67973639dbda6ecdedb1d1a4647b6d81
https://doi.org/10.1016/0002-9149(73)90932-6
https://doi.org/10.1016/0002-9149(73)90932-6