Výsledky vyhledávání - "F. J. Hendler"

Variation in cellular EGF receptor mRNA expression demonstrated byin situreverse transcriptase polymerase chain reaction

Autor: F. J. Hendler, A. Shum-Siu, M. Leonberger, B. W. Heniford

Publikováno v: Nucleic Acids Research. 21:3159-3166

Cell to cell variation of epidermal growth factor (EGF) receptor mRNA levels in heterogeneous tissues has been demonstrated with an in situ assay that couples reverse transcriptase with the polymerase chain reaction (in situ RT-PCR). EGF receptor mRN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a409e40aa035cb1a8149e85519194288
https://doi.org/10.1093/nar/21.14.3159

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Reverse Transcriptase PCR In Situ on Cryopreserved Tissue Sections

Autor: V J Patel, B. W. Heniford, Ahmed M el-M, F. J. Hendler, A. Shum-Siu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::20fa12b5639bd7fbe8b89d976ae2e0e8
https://doi.org/10.1385/0-89603-395-3:99

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Decreased expression of CD80 is a marker for increased tumorigenicity in a new murine model of oral squamous-cell carcinoma

Autor: G R, Thomas, Z, Chen, M N, Oechsli, F J, Hendler, C, Van Waes

Publikováno v: International journal of cancer. 82(3)

We established a new syngeneic murine model of oral squamous-cell carcinoma (SCC) to analyze the potential role of immune recognition determinants in the early development of oral cancer. In this study, we examined whether SCC that undergo transforma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2f87e670147fe78b0811764170d31687
https://pubmed.ncbi.nlm.nih.gov/10399955

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Consistent allelic loss on mouse chromosome 7 distal to tyrosinase in 4-nitroquinoline-1-oxide-induced oral cavity tumors with loss of heterozygosity at Ha-ras-1

Autor: B, Yuan, L H, Hu, E M, Lentsch, A, Shum-Siu, F J, Hendler

Publikováno v: Molecular carcinogenesis. 19(1)

We have previously shown that all CBA/J mice exposed to 4-nitroquinoline-1-oxide (4NQO) eventually develop oral cavity squamous cell carcinomas, and two-thirds of these tumors have Ha-ras-1 (Hras1) point mutations at codon 12. Half of the tumors with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::11622367822f390e546a08cffa194dff
https://pubmed.ncbi.nlm.nih.gov/9180923

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Reverse transcriptase PCR in situ on cryopreserved tissue sections

Autor: F J, Hendler, A, Shum-Siu, B W, Heniford, Ahmed M el-M, V J, Patel

Publikováno v: Methods in molecular biology (Clifton, N.J.). 71

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::edb0e765240543c141485f0d656e31d7
https://pubmed.ncbi.nlm.nih.gov/8959694

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Harvey ras (H-ras) point mutations are induced by 4-nitroquinoline-1-oxide in murine oral squamous epithelia, while squamous cell carcinomas and loss of heterozygosity occur without additional exposure

Autor: B, Yuan, B W, Heniford, D M, Ackermann, B L, Hawkins, F J, Hendler

Publikováno v: Cancer research. 54(20)

Tumorigenesis is a multistep genetic process requiring several somatic mutations for neoplastic transformation. These mutations appear to be sequential, random, and independent events. However, we find linked, nonrandom ras mutations occurring during

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::17f10f88853ee3b6d5b48312c1ea5fe4
https://pubmed.ncbi.nlm.nih.gov/7923158

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Effect of zoledronic acid on tartrate-resistant acid phosphatase isoform 5b (TRAP-5b) and other bone markers in lung cancer patients with bone metastasis

Autor: Guilherme Rabinowits, C. Li, L. Yam, A. J. Janckila, Damian A. Laber, Goetz H. Kloecker, W. Zhang, F. J. Hendler

Publikováno v: Journal of Clinical Oncology. 28:e18118-e18118

e18118 Background: Between 19 to 44% of patients with lung cancer eventually develop bone metastasis. Zoledronic acid (ZA), a bisphosphonate, can prevent skeletal-related complications in patients ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::89e9c388f72c8edea1d185df5ee3defd
https://doi.org/10.1200/jco.2010.28.15_suppl.e18118

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Update on a phase II study of cyclophosphamide, etoposide and estramustine in patients with androgen independent prostate cancer

Autor: R. V. La Rocca, P. U. Moffett, M. A. Choudry, L. A. Ferguson, F. J. Hendler, D. A. Williams, Damian A. Laber

Publikováno v: Journal of Clinical Oncology. 24:4647-4647

4647 Background: Oral therapy offers the tremendous advantage of independence and avoids all the catheter-related complications. Cyclophosphamide (C), etoposide (E) and estramustine (E) are active against androgen-independent prostate cancer (AIPC).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e5ab73b3cb391c48c366d0568f2aac9b
https://doi.org/10.1200/jco.2006.24.18_suppl.4647

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Update on the first phase I study of AGRO100 in advanced cancer

Autor: Vivek R. Sharma, B. Taft, K. M. Barnhart, Damian A. Laber, F. J. Hendler, L. Bhupalam

Publikováno v: Journal of Clinical Oncology. 23:3064-3064

3064 Background: AGRO100 is an oligonucleotide that functions as an aptamer and binds to nucleolin, a protein found intranuclear in all cells, but uniquely expressed on the surface of tumor cells. Such binding leads to internalization of the complex,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d3d0a2909af2d03d82aad51c7eabe326
https://doi.org/10.1200/jco.2005.23.16_suppl.3064

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