Výsledky vyhledávání

Detection and Local Staging of Prostate Cancer by 68Ga-PSMA-PET/CT, Comparison with mpMRI and Histopathology

Autor: J. M. H. de Klerk, W. Dingemans, G. K. Lammers, Anko Kooistra, A. Lont, F. Intema, R. M. Hoeben, M. C. Vermeulen, L. M. Andrews, A. M. van de Berk

Publikováno v: Advances in Molecular Imaging. 10:15-29

Introduction: 68Ga-PSMA-PET/CT has proven its value in prostate cancer with high positive predictive value for lymph node metastasis and superior detection of distant metastasis. There is growing evidence that 68Ga-PSMA- PET/CT has high sensitivity f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c701ae9a49dad4bdeeeccad803e1af9a
https://doi.org/10.4236/ami.2020.103003

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Five-Year Follow-up of Knee Joint Distraction: Clinical Benefit and Cartilaginous Tissue Repair in an Open Uncontrolled Prospective Study

Autor: Jan Ton A.D. van der Woude, Floris P J G Lafeber, Peter M. van Roermund, Roel J.H. Custers, Felix Eckstein, Jaap M van Laar, Simon C. Mastbergen, K. Wiegant, F. Intema

Publikováno v: Cartilage, 8(3), 263. SAGE Publications Inc.

Objective In end-stage knee osteoarthritis, total knee arthroplasty (TKA) may finally become inevitable. At a relatively young age, this comes with the risk of future revision surgery. Therefore, in these cases, joint preserving surgery such as knee

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c49880b2a9b8ce53b4d0f88b27ab639d
https://doi.org/10.1177/1947603516665442

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Tissue structure modification in knee osteoarthritis by use of joint distraction: an open 1-year pilot study

Autor: Floris P J G Lafeber, Peter M. van Roermund, Anne C. A. Marijnissen, Johannes W. J. Bijlsma, F. Intema, Felix Eckstein, Sebastian Cotofana, René M. Castelein, Simon C. Mastbergen

Publikováno v: Annals of the Rheumatic Diseases

Background Modification of joint tissue damage is challenging in late-stage osteoarthritis (OA). Few options are available for treating end-stage knee OA other than joint replacement. Objectives To examine whether joint distraction can effectively mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bd6cdb460e03c972d48c11eb11e3c21
https://doi.org/10.1136/ard.2010.142364

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In early OA, thinning of the subchondral plate is directly related to cartilage damage: results from a canine ACLT-meniscectomy model

Autor: D. Gouwens, Simon C. Mastbergen, Herman A.W. Hazewinkel, Jwj Bijlsma, F.P.J.G. Lafeber, Harrie Weinans, F. Intema

Publikováno v: Osteoarthritis and Cartilage, 18(5), 691-698. W.B. Saunders

Objective: The pathogenesis of osteoarthritis (OA) includes cartilage degeneration, synovial inflammation, and bone changes. Slowly, the sequence and inter-relationship of these features is becoming clearer. Early models of OA suggest thinning of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6644f63adf2dfa3f739cea9d6360f71
https://doi.org/10.1016/j.joca.2010.01.004

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The canine bilateral groove model of osteoarthritis

Autor: Floris P J G Lafeber, Bram Elshof, F. Intema, M. E. Vianen, Sue A. Yocum, Jeroen DeGroot, Anne-Marie Zuurmond, Simon C. Mastbergen

Publikováno v: Journal of Orthopaedic Research, 11, 26, 1471-1477

In studies aimed at local treatment of experimental osteoarthritis (OA) it is optimal to have an internal (untreated) OA control. Such an approach excludes interanimal variation, and allows paired statistical evaluation of treatment efficacy. For thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d5a04d51c87b464cc933ce53afbd00
https://doi.org/10.1002/jor.20681

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Evidence of cartilage repair by joint distraction in a canine model of osteoarthritis

Autor: Angelique D. Barten-Van Rijbroek, Arie Doornebal, Floris P J G Lafeber, F. Intema, Herman A.W. Hazewinkel, Simon C. Mastbergen, K. Wiegant, Peter M. van Roermund

Publikováno v: Arthritis & Rheumatology, 67(2), 465. John Wiley and Sons Ltd

Objective. Knee osteoarthritis (OA) is a degenerative joint disorder characterized by cartilage, bone, and synovial tissue changes that lead to pain and functional impairment. Joint distraction is a treatment that provides long-term improvement in pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c373e14f475f24aadf5be133d86f32ed
https://pubmed.ncbi.nlm.nih.gov/25303046

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Sustained clinical and structural benefit after joint distraction in the treatment of severe knee osteoarthritis

Autor: Floris Paulus Jacobus Gerardus Lafeber, K. Wiegant, P.M. van Roermund, F. Intema, Sebastian Cotofana, Felix Eckstein, S.C. Mastbergen

Publikováno v: Osteoarthritis and cartilage. 21(11)

SummaryBackgroundTreatment of severe osteoarthritis (OA) in relatively young patients is challenging. Although successful, total knee prosthesis has a limited lifespan, with the risk of revision surgery, especially in active young patients. Knee join

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b815e8ba24863bb381ec03cbfb533754
https://pubmed.ncbi.nlm.nih.gov/23954704

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A role for subchondral bone changes in the process of osteoarthritis; a micro-CT study of two canine models

Autor: Johannes P.T.M. van Leeuwen, Y.H. Sniekers, Simon C. Mastbergen, Harrie Weinans, Gerjo J.V.M. van Osch, F. Intema, Floris P J G Lafeber

Publikováno v: BioMed Central, 9. BioMed Central Ltd.
BMC Musculoskeletal Disorders
BMC Musculoskeletal Disorders, Vol 9, Iss 1, p 20 (2008)

Background This study evaluates changes in peri-articular bone in two canine models for osteoarthritis: the groove model and the anterior cruciate ligament transection (ACLT) model. Methods Evaluation was performed at 10 and 20 weeks post-surgery and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153049918b4753274afcc1cb112c4743
https://pure.eur.nl/en/publications/4f1a38a9-b439-4500-80dd-17147b1a1808

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Unloading joints to treat osteoarthritis, including joint distraction

Autor: Floris P J G Lafeber, Peter M. van Roermund, Anne C. A. Marijnissen, F. Intema

Publikováno v: Current opinion in rheumatology. 18(5)

Patients are increasingly becoming interested in nonpharmacologic approaches to manage their osteoarthritis. This review examines the recent literature on the potential beneficial effects of unloading joints in the treatment of osteoarthritis, with a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93dd63ed32fd0949ee0a5832cc6cdb70
https://pubmed.ncbi.nlm.nih.gov/16896294

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