Zobrazeno 1 - 7
of 7
pro vyhledávání: '"F. Holly Coleman"'
Publikováno v:
Neuroscience. 390
Stress plays a pivotal role in the development and/or exacerbation of functional gastrointestinal (GI) disorders. The paraventricular nucleus of the hypothalamus (PVN) contains neurons that are part of the hypothalamic-pituitary-adrenal axis as well
Autor:
Luca Toti, Tanja Babic, Gregory M. Holmes, Kirsteen N. Browning, R. Alberto Travagli, F. Holly Coleman
Publikováno v:
The Journal of Physiology. 592:4591-4605
Stress impairs gastric emptying, reduces stomach compliance and induces early satiety via vagal actions. We have shown recently that the ability of the anti-stress neuropeptide oxytocin (OXT) to modulate vagal brainstem circuits undergoes short-term
Autor:
Kirsteen N. Browning, Tanja Babic, Gregory M. Holmes, R. Alberto Travagli, F. Holly Coleman, Samuel R. Fortna
Publikováno v:
The Journal of Physiology. 591:3081-3100
Oxytocin (OXT) inputs to the dorsal vagal complex (DVC; nucleus of the tractus solitarius (NTS) dorsal motor nucleus of the vagus (DMV) and area postrema) decrease gastric tone and motility. Our first aim was to investigate the mechanism(s) of OXT-in
Autor:
Hiyuan Zheng, Kirsteen N. Browning, R. Alberto Travagli, F. Holly Coleman, Shuxia Wan, Hans-Rudolf Berthoud, Gregory M. Sutton, Andrew A. Butler
Publikováno v:
The Journal of Neuroscience. 28:4957-4966
The nucleus tractus solitarius (NTS) integrates visceral sensory signals with information from the forebrain to control homeostatic functions, including food intake. Melanocortin 3/4 receptor (MC3/4R) ligands administered directly to the caudal brain
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 293:G484-G492
It is known that cholecystokinin (CCK) acts in a paracrine fashion to increase pancreatic exocrine secretion via vagal circuits. Recent evidence, however, suggests that CCK-8s actions are not restricted to afferent vagal fibers, but also affect brain
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 289:G209-G219
We investigated the pre- and postsynaptic effects of pancreatic polypeptide (PP) on identified pancreas-projecting neurons of the rat dorsal motor nucleus of the vagus in thin brain stem slices. Perfusion with PP induced a TTX- and apamin-sensitive,
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 288:G950-G955
The electrophysiological and morphological properties of rat dorsal motor nucleus of the vagus (DMV) neurons innervating the pancreas were examined by using whole cell patch clamp recordings from brain stem slices and postfixation morphological recon