Zobrazeno 1 - 10
of 89
pro vyhledávání: '"F. Hoffschir"'
Autor:
R. Cassingena, S. Estrade, M. Ricoul, Anne Bravard, C. Luccioni, F. Hoffschir, Bernard Dutrillaux
Publikováno v:
Carcinogenesis. 14:21-24
The activities of several enzymes involved in the antioxidant system of the cell were studied in parallel to cytogenetic alterations at various times after SV40 infection and transformation of human fibroblasts. At early passages after SV40 infection
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Publikováno v:
International Journal of Cancer. 52:130-136
A comparative study of chromosomal rearrangements occurring in 4 independent clones obtained from SV40-transformed cornea and skin human fibroblasts was performed. Rearrangements principally affect some constitutive heterochromatin and, to a lesser d
Publikováno v:
Free radical biologymedicine. 35(1)
The SW620IR1 cell line was derived from SW620 human colon cells surviving to ionizing radiations. It shows an increased radiosensitivity and a higher yield of spontaneous chromosomal aberrations. In order to check whether altered reactive oxygen inte
Autor:
B. Dutrillaux, I. Testard, Michelle Ricoul, A. Flury-Herard, V. Gerasimenko, F. Hoffschir, Laure Sabatier, B. Fedorenko
Publikováno v:
International journal of radiation biology. 70(4)
The increased number of manned space missions has made it important to estimate the biological risks encountered by astronauts. As they are exposed to cosmic rays, especially ions with high linear energy transfer (LET), it is necessary to estimate th
Autor:
L. Sabatier, S. Estrade, Régis Calvayrac, M. Ricoul, F. Hoffschir, Alain Sarasin, Bernard Dutrillaux, Monique Vuillaume, R. Cassingena, Leela Daya-Grosjean
Publikováno v:
Carcinogenesis. 14(8)
The activity of catalase, a key enzyme in cell detoxication of oxygen derivatives, was studied in SV40 transformed human fibroblasts. A cytogenetic study was performed in parallel to establish a quantification of 11p arm on which the corresponding ge
Autor:
Eugénie Lamoliatte, D. Lefrançois, Michèle Gerbault-Seureau, Alain Aurias, Michèle Ricoul, Jérôme Couturier, Florence Richard, V. Volobouev, Anne-Marie Dutrillaux, Evani Viegas-Péquignot, Anne Flüry-Hérard, Laure Sabatier, Bernard Dutrillaux, F. Hoffschir, M. Lombard, Marguerite Prieur, Martine Muleris
Publikováno v:
Mutation research. 295(2)
Data on aneuploidy from a prospective study on a large number of lymphocyte metaphases (over 1000 in 72-h and 100 in 48-h cultures) per individual from eight healthy donors of various ages are reported. Chromosome losses were dependent on culture tim
Autor:
R. Cassingena, C. Luccioni, Laure Sabatier, A. Bravard, S. Estrade, Alain Pinton, F. Hoffschir, Bernard Dutrillaux, M. Ricoul
Publikováno v:
International journal of cancer. 52(5)
The expression of superoxide dismutases (SOD) 1 and 2 was studied in 4 clones of human fibroblasts after their infection by simian virus 40 (SV40), in parallel with the alterations of chromosomes 21 and chromosome 6q arms, carrying the genes that enc
Publikováno v:
International journal of cancer. 51(3)
The activity of superoxide dismutases (SOD) 1 and 2 was analysed in correlation with mRNA and chromosome content in 6 SV40-transformed (TF) and in non-transformed (NF) human fibroblast cell lines. Total SOD activity was fairly constant, whereas the r
Autor:
Evani Viegas-Péquignot, A. Bravard, Michelle Ricoul, Bernard Dutrillaux, M. Baumgartner, F. Hoffschir
Publikováno v:
Cancer genetics and cytogenetics. 56(1)
SV40-transformed human fibroblasts exhibit characteristic chromosome imbalances, fairly well correlated with the activity of enzymes encoded by genes located on chromosome segments either in deficiency or in excess. However, a major discrepancy exist