Zobrazeno 1 - 10
of 845
pro vyhledávání: '"F. Hauser"'
Autor:
Austin M. Jones, Kara M. Rademeyer, Elias P. Rosen, Silas Contaifer, Dayanjan Wijesinghe, Kurt F. Hauser, MaryPeace McRae
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 10, Pp n/a-n/a (2024)
Abstract Despite combination antiretroviral therapy effectively suppressing HIV within the periphery, neuro‐acquired HIV (neuroHIV) remains a significant problem and approximately half of people living with HIV will experience HIV‐associated neur
Externí odkaz:
https://doaj.org/article/0b548e664528400e88f0cc0fa2ab534e
Autor:
Michael Ohene-Nyako, Sara R. Nass, Hope T. Richard, Robert Lukande, Melanie R. Nicol, MaryPeace McRae, Pamela E. Knapp, Kurt F. Hauser
Publikováno v:
ASN Neuro, Vol 15 (2023)
Aberrant phosphorylation and subsequent aggregation of the trans-activation response (TAR) element DNA binding protein 43 (TDP-43) is a common feature of multiple neurodegenerative disorders and contributes to disease severity. Here, we investigated
Externí odkaz:
https://doaj.org/article/40944578bd644a5e9ee9fadf91aff448
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Opioid use disorder (OUD) is a critical problem that contributes to the spread of HIV and may intrinsically worsen neuroHIV. Despite the advent of combined antiretroviral therapies (cART), about half of persons infected with HIV (PWH) experience cogn
Externí odkaz:
https://doaj.org/article/794d623f615d423caa4d007d496ffa56
Autor:
Douglas J. Hermes, Ian R. Jacobs, Megan C. Key, Alexis F. League, Barkha J. Yadav-Samudrala, Changqing Xu, Virginia D. McLane, Sara R. Nass, Wei Jiang, Rick B. Meeker, Bogna M. Ignatowska-Jankowska, Aron H. Lichtman, Zibo Li, Zhanhong Wu, Hong Yuan, Pamela E. Knapp, Kurt F. Hauser, Sylvia Fitting
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-26 (2020)
Abstract Background Human immunodeficiency virus type-1 (HIV-1) and opiates cause long-term inflammatory insult to the central nervous system (CNS) and worsen disease progression and HIV-1-related neuropathology. The combination of these proinflammat
Externí odkaz:
https://doaj.org/article/9e4741df53be4e07958134c87b308da3
Autor:
Sara R. Nass, Yun K. Hahn, Michael Ohene-Nyako, Virginia D. McLane, M. Imad Damaj, Leroy R. Thacker, Pamela E. Knapp, Kurt F. Hauser
Publikováno v:
Viruses, Vol 15, Iss 3, p 590 (2023)
Opioid use disorder (OUD) and HIV are comorbid epidemics that can increase depression. HIV and the viral protein Tat can directly induce neuronal injury within reward and emotionality brain circuitry, including the prefrontal cortex (PFC). Such damag
Externí odkaz:
https://doaj.org/article/5268e4498a2d4d1f9e58f8b18d1037fa
Publikováno v:
ASN Neuro, Vol 13 (2021)
People infected with HIV (PWH) are highly susceptible to striatal and hippocampal damage. Motor and memory impairments are common among these patients, likely as behavioral manifestations of damage to these brain regions. GABAergic dysfunction from H
Externí odkaz:
https://doaj.org/article/b0db22fe778a4366ae859dcb815f3f00
Autor:
Kelly M. Flounlacker, Yun Kyung Hahn, Ruqiang Xu, Chloe A. Simons, Tao Tian, Kurt F. Hauser, Pamela E. Knapp
Publikováno v:
Journal of NeuroVirology. 29:15-26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19f910add0507e64f490b7437969e360
https://doi.org/10.1007/s13365-022-01107-x
https://doi.org/10.1007/s13365-022-01107-x
Publikováno v:
Neurobiology of Disease, Vol 141, Iss , Pp 104878- (2020)
Approximately half of people infected with HIV (PWH) exhibit HIV-associated neuropathology (neuroHIV), even when receiving combined antiretroviral therapy. Opiate use is widespread in PWH and exacerbates neuroHIV. While neurons themselves are not inf
Externí odkaz:
https://doaj.org/article/1fdc43de988d40cfaea1e3d20be7cbfe
Autor:
Sara R. Nass, Yun K. Hahn, Virginia D. McLane, Neil B. Varshneya, M. Imad Damaj, Pamela E. Knapp, Kurt F. Hauser
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 5, Iss , Pp 100077- (2020)
HIV-1 selectively disrupts neuronal integrity within specific brain regions, reflecting differences in viral tropism and/or the regional differences in the vulnerability of distinct neuronal subpopulations within the CNS. Deficits in prefrontal corte
Externí odkaz:
https://doaj.org/article/36d781f16f68483aa88fb1011fa10433
Autor:
Jason J. Paris, Philippe Liere, Sarah Kim, Fakhri Mahdi, Meagan E. Buchanan, Sara R. Nass, Alaa N. Qrareya, Mohammed F. Salahuddin, Antoine Pianos, Neïké Fernandez, Zia Shariat-Madar, Pamela E. Knapp, Michael Schumacher, Kurt F. Hauser
Publikováno v:
Neurobiology of Stress, Vol 12, Iss , Pp - (2020)
Pregnane steroids, particularly allopregnanolone (AlloP), are neuroprotective in response to central insult. While unexplored in vivo, AlloP may confer protection against the neurological dysfunction associated with human immunodeficiency virus type
Externí odkaz:
https://doaj.org/article/1eae79c386794b818bb6eb4c7ba81e75