Zobrazeno 1 - 10
of 26
pro vyhledávání: '"F. Gaudiano"'
Autor:
Arlene H. Sharpe, Marcia C. Haigis, Justin D. Trombley, Vikram R. Juneja, Kiran Kurmi, Cong-Hui Yao, Alison E. Ringel, Martin W. LaFleur, Isaac S. Harris, Emily F. Gaudiano, Thao H. Nguyen, Tara Muijlwijk, Jacob E. Gillis, Jefte M. Drijvers
Supplementary Figure and Table Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5626481bdf20fe17e9420d14ae280ac8
https://doi.org/10.1158/2326-6066.22543842.v1
https://doi.org/10.1158/2326-6066.22543842.v1
Autor:
Arlene H. Sharpe, Marcia C. Haigis, Justin D. Trombley, Vikram R. Juneja, Kiran Kurmi, Cong-Hui Yao, Alison E. Ringel, Martin W. LaFleur, Isaac S. Harris, Emily F. Gaudiano, Thao H. Nguyen, Tara Muijlwijk, Jacob E. Gillis, Jefte M. Drijvers
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ed5bd45f25fdeb87ae7c177752dece
https://doi.org/10.1158/2326-6066.22543839.v1
https://doi.org/10.1158/2326-6066.22543839.v1
Autor:
Arlene H. Sharpe, Marcia C. Haigis, Justin D. Trombley, Vikram R. Juneja, Kiran Kurmi, Cong-Hui Yao, Alison E. Ringel, Martin W. LaFleur, Isaac S. Harris, Emily F. Gaudiano, Thao H. Nguyen, Tara Muijlwijk, Jacob E. Gillis, Jefte M. Drijvers
Supplementary Table S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d3ee59855a43f56797cd02ff8922fe4
https://doi.org/10.1158/2326-6066.22543836.v1
https://doi.org/10.1158/2326-6066.22543836.v1
Autor:
Arlene H. Sharpe, Marcia C. Haigis, Justin D. Trombley, Vikram R. Juneja, Kiran Kurmi, Cong-Hui Yao, Alison E. Ringel, Martin W. LaFleur, Isaac S. Harris, Emily F. Gaudiano, Thao H. Nguyen, Tara Muijlwijk, Jacob E. Gillis, Jefte M. Drijvers
All dose-response curves. Dose-response curves for all library compounds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe0979e1b7484e2e9469ad43c6a3357
https://doi.org/10.1158/2326-6066.22543845.v1
https://doi.org/10.1158/2326-6066.22543845.v1
Autor:
Arlene H. Sharpe, Marcia C. Haigis, Justin D. Trombley, Vikram R. Juneja, Kiran Kurmi, Cong-Hui Yao, Alison E. Ringel, Martin W. LaFleur, Isaac S. Harris, Emily F. Gaudiano, Thao H. Nguyen, Tara Muijlwijk, Jacob E. Gillis, Jefte M. Drijvers
Metabolic constraints in the tumor microenvironment constitute a barrier to effective antitumor immunity and similarities in the metabolic properties of T cells and cancer cells impede the specific therapeutic targeting of metabolism in either popula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c0136f14266cee38042c4d6aaa2846
https://doi.org/10.1158/2326-6066.c.6550425.v1
https://doi.org/10.1158/2326-6066.c.6550425.v1
Autor:
Kathleen B. Yates, W. Nicholas Haining, Thao H. Nguyen, Rose Al Abosy, Debattama R. Sen, Arlene H. Sharpe, Gordon J. Freeman, Matthew A. Coxe, Jacob E. Gillis, Emily F. Gaudiano, Brian C. Miller, Martin W. LaFleur
Publikováno v:
Nature Immunology. 20:1335-1347
CD8+ T cell exhaustion is a state of dysfunction acquired in chronic viral infection and cancer, characterized by the formation of Slamf6+ progenitor exhausted and Tim-3+ terminally exhausted subpopulations through unknown mechanisms. Here we establi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::992756eca413d6aee6ab35f18e3ef5b5
https://doi.org/10.1038/s41590-019-0480-4
https://doi.org/10.1038/s41590-019-0480-4
Autor:
Jefte M, Drijvers, Jacob E, Gillis, Tara, Muijlwijk, Thao H, Nguyen, Emily F, Gaudiano, Isaac S, Harris, Martin W, LaFleur, Alison E, Ringel, Cong-Hui, Yao, Kiran, Kurmi, Vikram R, Juneja, Justin D, Trombley, Marcia C, Haigis, Arlene H, Sharpe
Publikováno v:
Cancer Immunol Res
Metabolic constraints in the tumor microenvironment constitute a barrier to effective anti-tumor immunity and similarities in the metabolic properties of T cells and cancer cells impede the specific therapeutic targeting of metabolism in either popul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5889aa75cd50f2d019b9006ae7bbf1b5
https://pubmed.ncbi.nlm.nih.gov/33277233
https://pubmed.ncbi.nlm.nih.gov/33277233
Autor:
Martin W, LaFleur, Thao H, Nguyen, Matthew A, Coxe, Brian C, Miller, Kathleen B, Yates, Jacob E, Gillis, Debattama R, Sen, Emily F, Gaudiano, Rose, Al Abosy, Gordon J, Freeman, W Nicholas, Haining, Arlene H, Sharpe
Publikováno v:
Nature immunology
CD8+ T cell exhaustion is a state of dysfunction acquired in chronic viral infection and cancer, characterized by the formation of Slamf6+ progenitor exhausted and Tim-3+ terminally exhausted subpopulations through unknown mechanisms. Here we establi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::783a739be5a8bbf996425cde6dc759a2
https://pubmed.ncbi.nlm.nih.gov/31527834
https://pubmed.ncbi.nlm.nih.gov/31527834
Autor:
Emma A. Roberts, Emily F. Gaudiano, Heng Li, Karthikeyan Ponnienselvan, Kalindi Parmar, Kah Suan Lim, David Kozono, Ning Zheng, Connor Clairmont, Jessica Liu, Chunyu Yang, Alan D. D'Andrea, Timur Yusufzai, Larissa A. Sambel
BRCA1 deficient tumor cells have defects in homologous-recombination repair and in replication fork stability, resulting in PARP inhibitor sensitivity. Here, we demonstrate that a deubiquitinase, USP1, is upregulated in tumors with mutations in BRCA1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d825d53ae5a16e453497fffb914bb2be
https://europepmc.org/articles/PMC6390489/
https://europepmc.org/articles/PMC6390489/
Autor:
Kalindi Parmar, David Kozono, Alix Rousseau, Alan D. D'Andrea, Emily F. Gaudiano, Jean Soulier, Grover C. Bagby, Kevin W O'Connor, Sofia Vidal-Cardenas, Lisa A. Moreau, Markus Grompe, Haojian Zhang, Joel S. Greenberger, Abigail Hamilton
Publikováno v:
Cell Stem Cell. 18:668-681
Fanconi anemia (FA) is an inherited DNA repair disorder characterized by progressive bone marrow failure (BMF) from hematopoietic stem and progenitor cell (HSPC) attrition. A greater understanding of the pathogenesis of BMF could improve the therapeu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ac1dc9b42affc5c95f6eb6d893914bc
https://doi.org/10.1016/j.stem.2016.03.002
https://doi.org/10.1016/j.stem.2016.03.002