Zobrazeno 1 - 10
of 20
pro vyhledávání: '"F. G. Cocu"'
Publikováno v:
Oftalmologia (Bucharest, Romania : 1990). 39(3)
The theoretical part of this paper presents the mechanism of the IOP lowering effect using these drugs, the indications of treatment and the main side effects. The second part consist of the experimental study made on rabbits, using the izopropilic e
Publikováno v:
Helvetica Chimica Acta. 57:1974-1987
On treatment with higher diazoalkanes, 2,4,6/3,5-penta-acetoxy-cyclohexanone (penta-O-acetyl-myo-inosose-2 or -scyllo-inosose) afforded by ring expansion all-trans-penta-acetoxy-C-alkyl-cycloheptanones, which by deacylation were converted to hemiacet
Publikováno v:
Helvetica Chimica Acta. 57:1963-1974
On treatment with diazomethane, 2,4,6/3,5-penta-acetoxy-cyclohexanone(penta-O-acetyl-myo-inosose-2 or -scyllo-inosose) gave only a spiroepoxide. In contrast, replacement of diazomethane by higher diazoalkanes furnished a mixture of alkylspiroepoxides
Autor:
F. G. Cocu, Th. Posternak
Publikováno v:
Helvetica Chimica Acta. 55:2838-2844
The conversion to free ketoses by transketalisation of ethylene-ketal and/or isopropylidene derivatives of polyhydroxy-cyclopentanones has been investigated. The preparation of 2, 3-dihydroxy-cyclopentanone and of 2, 3-dihydroxy-cyclopentenone has be
Publikováno v:
Helvetica Chimica Acta. 53:1511-1525
Several mono-, di-, and tri-hydroxy derivatives of cyclopentane and cyclopentene have been studied by NMR. spectroscopy. The chemical shifts and the coupling constants of the OH groups have been correlated with their position, with their configuratio
Publikováno v:
Helvetica Chimica Acta. 53:2275-2288
Two as yet unknown cyclopentene-triols have been prepared. The replacement of the halogen of cyclopentene derivatives brominated in the allylic position has been investigated. In the presence of dimethyl sulfoxide and sodium hydrogen carbonate, the b
Autor:
F. G. Cocu, Th. Posternak
Publikováno v:
Helvetica Chimica Acta. 54:1676-1687
All-cis cyclitols derived from cyclopentane have been prepared in two ways: (i) by LiAlH4 reduction of all-cis epoxypolyos; (ii) by dimethyl sulfoxide treatment, in the presence of sodium hydrogencarbonate, of brominated derivatives containing a neig
Autor:
Th. Posternak, F. G. Cocu
Publikováno v:
Helvetica Chimica Acta. 55:2828-2837
The synthesis of a series of keto derivatives of cyclopentane is described. The configurations of these derivatives have been determined by chemical methods and verified by IR. and NMR. spectroscopy. The preferred conformation of the cyclopentane par
Publikováno v:
Helvetica Chimica Acta. 53:2288-2295
Two new cyclopentane-pentols, namely the 1, 2, 3, 4/5- and 1, 2, 3/4, 5-isomers have been prepared by hydroxylation of the three 3, 4, 5-trihydroxy-1-cyclopentenes. The stereoselectivity of some hydroxylating agents is discussed.
Publikováno v:
Helvetica Chimica Acta. 53:739-749
Cyclopentenones substituted in position 4, and 3, 5-cis or -trans disubstituted cyclopentenes have been studied by NMR. and by IR. spectroscopy. Cyclopentenone derivatives and cyclopentene derivatives adopt a quasi-coplanar and an envelope conformati