Zobrazeno 1 - 10
of 42
pro vyhledávání: '"F. G. Allen"'
Publikováno v:
Cell Stress, Vol 4, Iss 5, Pp 99-113 (2020)
Mitophagy is thought to play a key role in eliminating damaged mitochondria, with diseases such as cancer and neurodegeneration exhibiting defects in this process. Mitophagy is also involved in cell differentiation and maturation, potentially through
Externí odkaz:
https://doaj.org/article/1b8d21e6f9d545558d24530cf3ed4ed3
Publikováno v:
Cell Stress
Cell Stress, Vol 4, Iss 5, Pp 99-113 (2020)
Cell Stress, Vol 4, Iss 5, Pp 99-113 (2020)
Mitophagy is thought to play a key role in eliminating damaged mitochondria, with diseases such as cancer and neurodegeneration exhibiting defects in this process. Mitophagy is also involved in cell differentiation and maturation, potentially through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::851366fe772b95fea1cd2889de41d9a6
http://europepmc.org/articles/PMC7212530
http://europepmc.org/articles/PMC7212530
Publikováno v:
EMBO Reports
Loss of iron triggers PINK1/Parkin-independent mitophagy A novel mitophagy assay uncovers a new PINK1/Parkin-independent mitophagy pathway induced by a decrease in iron levels. This pathway is active in fibroblasts of Parkinson patients with Parkin m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0ea812f7308304a77cd6abbda7062b4
https://doi.org/10.1038/embor.2013.168
https://doi.org/10.1038/embor.2013.168
Autor:
Julia C. Fitzgerald, Andrey Y. Abramov, Iain P. Hargreaves, Aslihan Ugun-Klusek, Luigi A. De Girolamo, George F. G. Allen, E. Ellen Billett, Christoph Ufer
Publikováno v:
The FASEB Journal. 28:218-229
The study examined how the mitochondrial enzyme monoamine oxidase-A (MAO-A), which produces hydrogen peroxide as a catalytic by-product, influences death and survival mechanisms. Targeted microRNA (miRNA) was used to stably knock down MAO-A mRNA, pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4a45d9108bd6aafcd72fa5d7ed6f198
https://doi.org/10.1096/fj.13-235481
https://doi.org/10.1096/fj.13-235481
Publikováno v:
Neurochemistry International. 62:684-694
Dopamine is produced first by hydroxylalation of l-tyrosine to l-dihydroxyphenylalanine (l-dopa) and subsequently by the decarboxylation of l-dopa to dopamine catalysed by the enzymes tyrosine hydroxylase and aromatic l-amino acid decarboxylase (AADC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9d803d91b953635d91193538d1f53f1
https://doi.org/10.1016/j.neuint.2012.12.004
https://doi.org/10.1016/j.neuint.2012.12.004
Autor:
Alan R. Prescott, Thomas G. McWilliams, George F. G. Allen, Michael J. Munson, Ian G. Ganley, Miratul M. K. Muqit, Calum Thomson, Jevgenia Tamjar
Publikováno v:
The Journal of Cell Biology
Whether mitophagy occurs within specific cellular subtypes in vivo is unclear. McWilliams et al. present “mito-QC,” a transgenic mouse containing a pH-sensitive fluorescent mitochondrial signal, allowing in vivo detection of mitophagy and mitocho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10bac5c0984b2c87147ee0433fc61288
https://pubmed.ncbi.nlm.nih.gov/27458135
https://pubmed.ncbi.nlm.nih.gov/27458135
Autor:
Philippa B. Mills, George F. G. Allen, Simon Heales, Marcus Oppenheim, Peter E. Clayton, Emma Footitt
Publikováno v:
Journal of Inherited Metabolic Disease. 34:529-538
Analysis of pyridoxal 5'-phosphate (PLP) concentration in 256 cerebrospinal fluid (CSF) samples from patients with neurological symptoms showed that the variance is greater than indicated by previous studies. The age-related lower reference limit has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16c7a2401212b91dd864e5b6cb7169b6
https://doi.org/10.1007/s10545-011-9279-7
https://doi.org/10.1007/s10545-011-9279-7
Autor:
John M. Lucocq, Ian G. Ganley, Michael J. Munson, Rachel Toth, George F. G. Allen, David G. Campbell
Funding provided by: Wellcome Trust Technology Platform 097945/B/11/Z, MRC Next Generation Optical Microscopy MR/K015869/1, Medical Research Council, Division of Signal Transduction Therapy Unit (AstraZeneca, Boehringer‐Ingelheim, GlaxoSmithKline,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b789569dc54078f42b45a03bda31947a
https://hdl.handle.net/10023/7029
https://hdl.handle.net/10023/7029
Autor:
F. G. Allen, G. W. Gobeli
Publikováno v:
Annals of the New York Academy of Sciences. 101:647-657
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30303f4052ac20c2bfb68fbbdb6c02b8
https://doi.org/10.1111/j.1749-6632.1963.tb54921.x
https://doi.org/10.1111/j.1749-6632.1963.tb54921.x
Autor:
F. G. Allen
Publikováno v:
Annals of the New York Academy of Sciences. 101:850-856
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72ad9419489ff139be84cb35dc7de373
https://doi.org/10.1111/j.1749-6632.1963.tb54941.x
https://doi.org/10.1111/j.1749-6632.1963.tb54941.x