Zobrazeno 1 - 10
of 360
pro vyhledávání: '"F. Fennell"'
Autor:
Joshua A. Lees, João M. Dias, Francis Rajamohan, Jean-Philippe Fortin, Rebecca O’Connor, Jimmy X. Kong, Emily A. G. Hughes, Ethan L. Fisher, Jamison B. Tuttle, Gabrielle Lovett, Bethany L. Kormos, Rayomand J. Unwalla, Lei Zhang, Anne-Marie Dechert Schmitt, Dahui Zhou, Michael Moran, Kimberly A. Stevens, Kimberly F. Fennell, Alison E. Varghese, Andrew Maxwell, Emmaline E. Cote, Yuan Zhang, Seungil Han
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract GPR61 is an orphan GPCR related to biogenic amine receptors. Its association with phenotypes relating to appetite makes it of interest as a druggable target to treat disorders of metabolism and body weight, such as obesity and cachexia. To d
Externí odkaz:
https://doaj.org/article/5d8246b6d9824727b8ad761786a5eac1
Autor:
S. N. F. Chepuri, A. N. Jaynes, D. L. Turner, C. Gabrielse, I. J. Cohen, D. N. Baker, B. H. Mauk, T. Leonard, J. B. Blake, J. F. Fennell
Publikováno v:
Frontiers in Astronomy and Space Sciences, Vol 10 (2023)
Betatron acceleration is commonly cited as a primary accelerator of energetic electrons at dipolarization fronts, and many case studies compare observed energetic electrons measurements to a betatron model. In this work, we extend this to a statistic
Externí odkaz:
https://doaj.org/article/18dc7fbd0b9b41efa1cc6e5578fd3fe4
Autor:
S. N. F. Chepuri, A. N. Jaynes, D. L. Turner, C. Gabrielse, D. N. Baker, B. H. Mauk, I. J. Cohen, T. Leonard, J. B. Blake, J. F. Fennell
Publikováno v:
Frontiers in Astronomy and Space Sciences, Vol 9 (2023)
In this study, we examine particle energization and injections that show energetic electron enhancements at both MMS in the magnetotail and Van Allen Probes in the inner magnetosphere. Observing injections along with a corresponding flow burst allows
Externí odkaz:
https://doaj.org/article/78fe8c17ef864674a9dd167b2eabe9ec
Autor:
Somnath Mukherjee, Satchal K. Erramilli, Mark Ammirati, Frances J. D. Alvarez, Kimberly F. Fennell, Michael D. Purdy, Blazej M. Skrobek, Katarzyna Radziwon, John Coukos, Yanyong Kang, Przemysław Dutka, Xiang Gao, Xiayang Qiu, Mark Yeager, H. Eric Xu, Seungil Han, Anthony A. Kossiakoff
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Single particle cryo-electron microscopy of membrane proteins is limited by their small size and difficulty to orient. Here the authors generate recombinant antibodies against the 12 kDa fusion partner BRIL domain from apocytochrome b562 to use them
Externí odkaz:
https://doaj.org/article/c4e601bd5c28456ba07689558d4667e5
Autor:
Zachary Lee Johnson, Mark Ammirati, David Jonathan Wasilko, Jeanne S. Chang, Stephen Noell, Timothy L. Foley, Hyejin Yoon, Kathleen Smith, Shoh Asano, Katherine Hales, Min Wan, Qingyi Yang, Mary A. Piotrowski, Kathleen A. Farley, Tamara Gilbert, Lisa M. Aschenbrenner, Kimberly F. Fennell, Jason K. Dutra, Mary Xu, Chunyang Guo, Alison E. Varghese, Justin Bellenger, Alandra Quinn, Christopher W. am Ende, Graham M. West, Matthew C. Griffor, Donald Bennett, Matthew Calabrese, Claire M. Steppan, Seungil Han, Huixian Wu
Publikováno v:
Nature Structural & Molecular Biology. 30:22-30
Glycerol-3-phosphate acyltransferase (GPAT)1 is a mitochondrial outer membrane protein that catalyzes the first step of de novo glycerolipid biosynthesis. Hepatic expression of GPAT1 is linked to liver fat accumulation and the severity of nonalcoholi
Autor:
R. Shi, W. Li, Q. Ma, S. G. Claudepierre, C. A. Kletzing, W. S. Kurth, G. B. Hospodarsky, H. E. Spence, G. D. Reeves, J. F. Fennell, J. B. Blake, S. A. Thaller, J. R. Wygant
Publikováno v:
Annales Geophysicae, Vol 36, Pp 781-791 (2018)
Plasmaspheric hiss was observed by Van Allen Probe B in association with energetic electron injections in the outer plasmasphere. The energy of injected electrons coincides with the minimum resonant energy calculated for the observed hiss wave fre
Externí odkaz:
https://doaj.org/article/46ae7c4f3ea94d90bfc7095db2130a9c
Autor:
Joshua A. Lees, João M. Dias, Francis Rajamohan, Jean-Philippe Fortin, Rebecca O’Connor, Jimmy X. Kong, Emily Hughes, Ethan L. Fisher, Jamison B. Tuttle, Gabrielle Lovett, Bethany L. Kormos, Rayomand J. Unwalla, Lei Zhang, Anne-Marie Dechert Schmidt, Dahui Zhou, Kimberly A. Stevens, Kimberly F. Fennell, Alison E. Varghese, Andrew Maxwell, Emmaline E. Cote, Yuan Zhang, Seungil Han
GPR61 is a biogenic amine receptor-related orphan GPCR associated with phenotypes relating to appetite and thus, is of interest as a druggable target to treat disorders of metabolism and body weight, such as obesity and cachexia. To date, lack of str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76acb6e0af1f71354ac4bc6320c62e67
https://doi.org/10.1101/2023.05.01.538732
https://doi.org/10.1101/2023.05.01.538732
Autor:
Allyn T. Londregan, Karlygash Aitmakhanova, James Bennett, Laura J. Byrnes, Daniel P. Canterbury, Xiayun Cheng, Thomas Christott, Jennifer Clemens, Steven B. Coffey, João M. Dias, Matthew S. Dowling, Gillian Farnie, Oleg Fedorov, Kimberly F. Fennell, Vicki Gamble, Carina Gileadi, Charline Giroud, Michael R. Harris, Brett D. Hollingshead, Kilian Huber, Magdalena Korczynska, Kimberly Lapham, Paula M. Loria, Arjun Narayanan, Dafydd R. Owen, Brigitt Raux, Parag V. Sahasrabudhe, Roger B. Ruggeri, Laura Díaz Sáez, Ingrid A. Stock, Benjamin A. Thuma, Andy Tsai, Alison E. Varghese
Publikováno v:
Journal of medicinal chemistry.
A series of small-molecule YEATS4 binders have been discovered as part of an ongoing research effort to generate high-quality probe molecules for emerging and/or challenging epigenetic targets. Analogues such as
Autor:
Howard J. Singer, Juan V. Rodriguez, Brian Kress, Hong Zhao, Xinlin Li, Seth G. Claudepierre, V. Hoxie, Shrikanth Kanekal, Daniel N. Baker, J. F. Fennell, Allison Jaynes
Publikováno v:
Journal of Geophysical Research: Space Physics. 124:9924-9942
Autor:
Sasha Ukhorskiy, J. Bernard Blake, Kareem A. Sorathia, A. Michael, Drew Turner, Geoffrey D. Reeves, Slava Merkin, Jean-Francois Ripoll, Christine Gabrielse, Joseph F. Fennell, Alexander Drozdov, Barry Mauk, Seth G. Claudepierre, Ian J. Cohen, Allison Jaynes, Kyle Murphy, A. J. Boyd
Publikováno v:
Geophysical Research Letters. 48