Zobrazeno 1 - 10
of 38
pro vyhledávání: '"F. Falson-Rieg"'
Publikováno v:
International Journal of Pharmaceutics, Vol. 231, No 1 (2002) pp. 1-9
The ex vivo permeation of an acylated model dipeptide, Myristoyl-Tryptophan-Leucine (Myr-Trp-Leu) was studied using pig buccal mucosa. Myr-Trp-Leu, being lipophilic, did not readily penetrate across the membrane. Rather, it accumulated in the epithel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac661ea0b55b8df0fdb39f55ca5ac7ee
https://doi.org/10.1016/s0378-5173(01)00850-x
https://doi.org/10.1016/s0378-5173(01)00850-x
Publikováno v:
Pharmaceutical Research. 16:1449-1455
Purpose. Elucidate the compactibility of binary mixes from their organization as compared to the traditional approach involving the different behavior of the materials under compression (plastic or brittle).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db67d14e4299fe5c2859401198adc079
https://doi.org/10.1023/a:1018967529128
https://doi.org/10.1023/a:1018967529128
Publikováno v:
International Journal of Pharmaceutics, Vol. 170, No 1 (1998) pp. 85-91
The ex vivo permeation of a model peptide, tryptophan-leucine (Trp-Leu), was studied using two different regions of pig oral mucosa, the hard palate and the cheek. In order to increase the mucosal absorption of Trp-Leu, a lipophilic derivative was sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb25365ddaa106ef2a5b9dd1c15c5f1
https://doi.org/10.1016/s0378-5173(98)00134-3
https://doi.org/10.1016/s0378-5173(98)00134-3
Publikováno v:
Pharmaceutical Research. 15:495-498
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81e4e7af8c5340550a6d91935a4c4e41
https://doi.org/10.1023/a:1011949020351
https://doi.org/10.1023/a:1011949020351
Publikováno v:
Pharmaceutical Research. 15:1727-1736
Purpose. The aim of this study was to relate the organization of several binary mixes with three physical parameters (surface energy, cohesion parameter, and particle size) of various materials blended with each other.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c50b9475f77de14df76df2a7b79fceb5
https://doi.org/10.1023/a:1011960712908
https://doi.org/10.1023/a:1011960712908
Publikováno v:
International Journal of Pharmaceutics, Vol. 156, No 2 (1997) pp. 127-142
This paper reviews the effects of a diverse range of penetration enhancers, including fatty acids, bile salts, surfactants, Azone® and ethanol, on oral mucosa. We describe in detail the effects on the intercellular lipid domains, the changes induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a8cc21c204cabac57b77de83e078163
https://doi.org/10.1016/s0378-5173(97)00193-2
https://doi.org/10.1016/s0378-5173(97)00193-2
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics, Vol. 44, No 2 (1997) pp. 107-120
The aim of this paper is to review the lipid composition of different regions of the oral mucosa, bearing in mind that, in general, molecular diffusion occurs through the intercellular lipids. Lipid content and organization is described to explain th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a474eecb8a8e9174c4cc67a3f3abfbd
https://doi.org/10.1016/s0939-6411(97)00080-5
https://doi.org/10.1016/s0939-6411(97)00080-5
Evaluation of the transepidermal permeation of diethylene glycol monoethyl ether and skin water loss
Publikováno v:
International Journal of Pharmaceutics, Vol. 147, No 2 (1997) pp. 165-171
The rate of Transcutol® (TC)-water interchange, was studied using whole and stripped hairless rat skin in a modified vertical Franz diffusion cell. The presence of stratum corneum limited the passage of the two solvents, but after stripping of the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7801044e5301f4e77cdb3dc11a3eaf79
https://doi.org/10.1016/s0378-5173(96)04809-0
https://doi.org/10.1016/s0378-5173(96)04809-0
Publikováno v:
Pharmaceutical research. 16(9)
Elucidate the compactibility of binary mixes from their organization as compared to the traditional approach involving the different behavior of the materials under compression (plastic or brittle).Several materials were selected from their surface e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3eb9d3b78445b42701b2de4769949a42
https://pubmed.ncbi.nlm.nih.gov/10496664
https://pubmed.ncbi.nlm.nih.gov/10496664
Publikováno v:
Pharmaceutical research. 15(11)
The aim of this study was to relate the organization of several binary mixes with three physical parameters (surface energy, cohesion parameter, and particle size) of various materials blended with each other.Four pharmaceutical compounds were select
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::820b56b19b5ac45d3a51250ee3b0722e
https://pubmed.ncbi.nlm.nih.gov/9833995
https://pubmed.ncbi.nlm.nih.gov/9833995