Výsledky vyhledávání - "F. F. Weichold"

HIV-1 suppression of hematopoiesis in vitro mediated by envelope glycoprotein and TNF-alpha

Autor: J P Maciejewski, F F Weichold, N S Young

Publikováno v: The Journal of Immunology. 153:4303-4310

Dysmorphic marrow morphology and bone marrow failure are common in AIDS patients, but the mechanism of HIV-1 effects on blood cell production is unclear. Experiments to test the susceptibility of hematopoietic progenitor cells to HIV-1 infection have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::221170632095ea193930929bbeafad45
https://doi.org/10.4049/jimmunol.153.9.4303

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Intraembryonic avian leukosis virus subgroup C (ALV-C) inoculation producing wasting disease in ducks soon after hatching

Autor: V, Stepanets, Z, Vernerová, M, Vilhelmová, J, Geryk, J, Plachý, J, Hejnar, F F, Weichold, J, Svoboda

Publikováno v: Folia biologica. 49(3)

We have studied the pathogenic changes in Khaki Campbell ducks injected in mid embryogenesis with ALV subgroup C virus td daPR-C derived from a molecular clone. The employed duck flock was shown to be highly genetically homogeneous and was controlled

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::149d5432a9d3dcc6fa09975c639b81e1
https://pubmed.ncbi.nlm.nih.gov/12859018

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HIV-1 protease inhibitor ritonavir modulates susceptibility to apoptosis of uninfected T cells

Autor: F F, Weichold, J L, Bryant, S, Pati, O, Barabitskaya, R C, Gallo, M S, Reitz

Publikováno v: Journal of human virology. 2(5)

Clinical experience with HIV-1 protease inhibitors (PIs) in the treatment of AIDS frequently has shown that increases in CD4+ T-cell counts can be independent of HIV-1 inhibition by these drugs. This disconnection between viral load and CD4 counts le

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3f55f499723489c6ce75e1dd874bd557
https://pubmed.ncbi.nlm.nih.gov/10551732

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Recombinant IFN-alpha (2b) increases the expression of apoptosis receptor CD95 and chemokine receptors CCR1 and CCR3 in monocytoid cells

Autor: D, Zella, O, Barabitskaja, L, Casareto, F, Romerio, P, Secchiero, M S, Reitz, R C, Gallo, F F, Weichold

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 163(6)

IFN-alpha-2b, known as potent immune modulator, can either inhibit or enhance immune cell activity within the tightly regulated microenvironment of inflammation, depending upon the concentration of the cytokine and the activation stage of the cell. C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4c75eb659675b86e9e202d9edbdff5b7
https://pubmed.ncbi.nlm.nih.gov/10477584

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Interferon-gamma increases expression of chemokine receptors CCR1, CCR3, and CCR5, but not CXCR4 in monocytoid U937 cells

Autor: D, Zella, O, Barabitskaja, J M, Burns, F, Romerio, D E, Dunn, M G, Revello, G, Gerna, M S, Reitz, R C, Gallo, F F, Weichold

Publikováno v: Blood. 91(12)

Chemokine receptors (CR), which can mediate migration of immune cells to the site of inflammation, also function as coreceptors for human immunodeficiency virus (HIV) entry into CD4+ T lymphocytes and antigen-presenting cells. We demonstrate here tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ce0b66d442b18f68d07af858ddc4d685
https://pubmed.ncbi.nlm.nih.gov/9616137

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Neither human immunodeficiency virus-1 (HIV-1) nor HIV-2 infects most-primitive human hematopoietic stem cells as assessed in long-term bone marrow cultures

Autor: F F, Weichold, D, Zella, O, Barabitskaja, J P, Maciejewski, D E, Dunn, E M, Sloand, N S, Young

Publikováno v: Blood. 91(3)

Attempts to clarify the pathophysiology of human immunodeficiency virus (HIV)-mediated bone marrow (BM) dysfunction have yielded inconsistent results regarding the susceptibility of BM progenitors to the viral infection. To specifically address this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0760f0266b5e0740c2639412efe3f75c
https://pubmed.ncbi.nlm.nih.gov/9446651

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Regulation of a graft-versus-leukemia effect by major histocompatibility complex class II molecules on leukemia cells: HLA-DR1 expression renders K562 cell tumors resistant to adoptively transferred lymphocytes in severe combined immunodeficiency mice/nonobese diabetic mice

Autor: F F, Weichold, Y Z, Jiang, D E, Dunn, M, Bloom, V, Malkovska, N F, Hensel, A J, Barrett

Publikováno v: Blood. 90(11)

To understand the role of key molecules in determining the strength and nature of allogeneic T-cell response to leukemia, we transfected HLA-DR1 into the major histocompatibility complex (MHC)-deficient, natural killer (NK)-cell sensitive K562 leukem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6ede61ec1cac0c44b4aaeff256320734
https://pubmed.ncbi.nlm.nih.gov/9373266

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Paroxysmal nocturnal hemoglobinuria: new insights from murine Pig-a-deficient hematopoiesis

Autor: M P, Devetten, J M, Liu, V, Ling, F F, Weichold, J, Yu, M E, Medof, N S, Young, D E, Dunn

Publikováno v: Proceedings of the Association of American Physicians. 109(2)

A large fraction of the hematopoietic cells of patients with paroxysmal nocturnal hemoglobinuria (PNH) are deficient in membrane expression of glycosylphosphatidylinositol-anchored proteins (GPI-APs). Current evidence suggests that this deficiency is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::206f87e8fa71f46483a5ba391ceec24c
https://pubmed.ncbi.nlm.nih.gov/9069578

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Role of Fas ligand and receptor in the mechanism of T-cell depletion in acquired immunodeficiency syndrome: effect on CD4+ lymphocyte depletion and human immunodeficiency virus replication

Autor: E M, Sloand, N S, Young, P, Kumar, F F, Weichold, T, Sato, J P, Maciejewski

Publikováno v: Blood. 89(4)

Direct killing of CD4+ lymphocytes by human immunodeficiency virus-1 (HIV-1) probably cannot account for the magnitude of the loss of these cells during the course of HIV-1 infection. Experimental evidence supports a pathophysiologic role of the apop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::85691bf25799b4e92afbe5c50e0859d2
https://pubmed.ncbi.nlm.nih.gov/9028959

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Activation of human CD4+ and CD8+ cells by Sarcocystis gigantea lectin

Autor: Tietz Hj, Thomas Montag, Gantenberg R, F. F. Weichold, H. D. Volk, E. Brose, Hiepe T

Publikováno v: Parasitology research. 77(7)

As recently reported,Sarcocystis gigantea lectin (SGL) is a powerful mitogen and a polyclonal activator (Syn.S. ovifelis) of human peripheral B-cells. In the present study we investigated the reactivity of human T-helper (CD4) and T-suppressor (CD8)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f3dc2f5670fe67f752f9027e1157fdd
https://pubmed.ncbi.nlm.nih.gov/1686494

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