Replacing the Draize eye test: impedance spectroscopy as a 3R method to discriminate between all GHS categories for eye irritation

Autor: C. Lotz, L. Kiesewetter, F. F. Schmid, J. Hansmann, H. Walles, F. Groeber-Becker

Publikováno v: Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)

Highly invasive animal based test procedures for risk assessment such as the Draize eye test are under increasing criticism due to poor transferability for the human organism and animal-welfare concerns. However, besides all efforts, the Draize eye t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3fdac619e47988e94329fa8c2a1bd4ae
https://doi.org/10.1038/s41598-018-33118-2

All-atom Simulations of Structures and Energetics of c-di-GMP-bound and free PleD

Autor: Markus Meuwly, Franziska F.-F. Schmid

Publikováno v: Journal of Molecular Biology. 374:1270-1285

Cyclic diguanosine monophosphate is a bacterial second messenger involved in a lifestyle switch from single cells to biofilm formation. Atomistic simulations are used to characterize inhibited diguanylate cyclase (DGC) PleD with emphasis on the feedb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b7227fd355126cdc63bc7e1e1fb3030
https://doi.org/10.1016/j.jmb.2007.09.068

Insulin: a model system for nanomedicine?

Autor: Franziska F.-F. Schmid, Manuela Koch, Markus Meuwly, Vincent Zoete

Publikováno v: Nanomedicine (London, England). 1(3)

One of the predominant aims of insulin therapy for diabetes is to appropriately mimic physiological insulin secretion levels and their correlation with glucose concentration in healthy individuals. This report outlines current methods and their limit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4be67b1815aed5d8177ce3bb5261251
https://pubmed.ncbi.nlm.nih.gov/17716170

Neural activations during cognitive and affective theory of mind processing in healthy adults with a family history of alcohol use disorder.

Autor: Schmid F; Laboratoire Cognition, Santé, Société (C2S - EA 6291), University of Reims Champagne-Ardenne, Reims, France., Henry A; Laboratoire Cognition, Santé, Société (C2S - EA 6291), University of Reims Champagne-Ardenne, Reims, France.; Psychiatry Department, Marne Public Mental Health Institute & Reims University Hospital, Reims, France., Benzerouk F; Psychiatry Department, Marne Public Mental Health Institute & Reims University Hospital, Reims, France.; INSERM U1247, Research Group on Alcohol and Dependences, University of Picardy Jules Verne, Amiens, France., Barrière S; Psychiatry Department, Marne Public Mental Health Institute & Reims University Hospital, Reims, France., Portefaix C; Radiology Department, Maison Blanche Hospital, Reims University Hospital, Reims, France.; Centre de Recherche en Sciences et Technologies de l'Information et de la Communication (CReSTIC - EA 3804), University of Reims Champagne-Ardenne, Reims, France., Gondrexon J; Psychiatry Department, Marne Public Mental Health Institute & Reims University Hospital, Reims, France., Obert A; Laboratoire Sciences de la Cognition, Technologie, Ergonomie (SCOTE - EA 7420), Champollion National University Institute, Albi, France., Kaladjian A; Laboratoire Cognition, Santé, Société (C2S - EA 6291), University of Reims Champagne-Ardenne, Reims, France.; Psychiatry Department, Marne Public Mental Health Institute & Reims University Hospital, Reims, France., Gierski F; Laboratoire Cognition, Santé, Société (C2S - EA 6291), University of Reims Champagne-Ardenne, Reims, France.; Psychiatry Department, Marne Public Mental Health Institute & Reims University Hospital, Reims, France.; INSERM U1247, Research Group on Alcohol and Dependences, University of Picardy Jules Verne, Amiens, France.

Publikováno v: Psychological medicine [Psychol Med] 2024 Apr; Vol. 54 (5), pp. 1034-1044. Date of Electronic Publication: 2023 Sep 27.

Model reduction techniques for the computation of extended Markov parameterizations for generalized Langevin equations.

Autor: Bockius N; Institut für Mathematik, Johannes Gutenberg-Universität Mainz, 55099 Mainz, Germany., Shea J; Institut für Physik, Johannes Gutenberg-Universität Mainz, 55099 Mainz, Germany., Jung G; Institut für Theoretische Physik, Universität Innsbruck, Technikerstraße 21A, A-6020 Innsbruck, Austria., Schmid F; Institut für Physik, Johannes Gutenberg-Universität Mainz, 55099 Mainz, Germany., Hanke M; Institut für Mathematik, Johannes Gutenberg-Universität Mainz, 55099 Mainz, Germany.

Publikováno v: Journal of physics. Condensed matter : an Institute of Physics journal [J Phys Condens Matter] 2021 May 03; Vol. 33 (21). Date of Electronic Publication: 2021 May 03.