Zobrazeno 1 - 10
of 433
pro vyhledávání: '"F. Eusebi"'
Publikováno v:
Progress in Neurobiology. 88:32-40
Despite huge improvements in neurobiological approaches for investigating the functional properties of neurotransmitter receptors and ion channels, many difficulties are still encountered when focusing on the human brain. Electrophysiological studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52e89aadf714b0a52ab049460b647f33
https://doi.org/10.1016/j.pneurobio.2009.01.008
https://doi.org/10.1016/j.pneurobio.2009.01.008
Autor:
M. Amici, S. Di Angelantonio, Addolorata Mascia, G. Spinelli, Fabrizia Sobrero, Davide Ragozzino, C. Scoppetta, F. Eusebi, Eleonora Palma, Ricardo Miledi, Vincenzo Esposito
Publikováno v:
Proceedings of the National Academy of Sciences. 103:8465-8468
The mRNA levels of NKCC1, an inwardly directed Na + , K + -2Cl − cotransporter that facilitates the accumulation of intracellular Cl − , and of KCC2, an outwardly directed K + -Cl − cotransporter that extrudes Cl − , were studied in surgicall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc597c81ffac80d2761b1c35e5438cbb
https://doi.org/10.1073/pnas.0602979103
https://doi.org/10.1073/pnas.0602979103
Publikováno v:
Proceedings of the National Academy of Sciences. 97:3643-3648
A cDNA coding for the human neuronal nicotinic alpha7 receptor subunit with Leu-248 mutated to threonine was expressed in Xenopus oocytes. When activated by acetylcholine (AcCho), the receptors expressed generated currents that had low desensitizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f4e38338a1cce3a2633884b75d1ef4e
https://doi.org/10.1073/pnas.050582497
https://doi.org/10.1073/pnas.050582497
Publikováno v:
Proceedings of the National Academy of Sciences. 94:9915-9919
Mutation of the highly conserved leucine residue (Leu-247) converts 5-hydroxytryptamine (5HT) from an antagonist into an agonist of neuronal homomeric α 7 nicotinic acetylcholine receptor expressed in Xenopus oocytes. We show here that acetylcholine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23fc035e2471376cbc4686fc972a8ee5
https://doi.org/10.1073/pnas.94.18.9915
https://doi.org/10.1073/pnas.94.18.9915
Autor:
Cristina Limatola, Eleonora Palma, Francesca Grassi, F. Eusebi, Anna Maria Mileo, Stefano Alemà, Barabino B, Marc Ballivet, Sergio Fucile
Publikováno v:
Scopus-Elsevier
nAChRs heterologously expressed in human cells after transient transfection with alpha 3 beta 4 alpha 5 or alpha 3 beta 4 subunit cDNAs exhibited similar sensitivities to antagonists and comparable functional channel profiles. However, the sum of two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87ab7ed9c5e8a4fa8ed1176d16a92666
https://doi.org/10.1097/00001756-199707280-00005
https://doi.org/10.1097/00001756-199707280-00005
Autoimmune myasthenia gravis (MG) is a heterogenous disorder. In young women, the thymus gland is often hyperplastic, and the patients respond well to thymectomy. However, in the increasing number of patients over the age of 40 years, predominantly m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89163451b2bfc88228e1aee08ad4b7a2
https://europepmc.org/articles/PMC1738331/
https://europepmc.org/articles/PMC1738331/
Publikováno v:
British journal of pharmacology. 126(1)
1. We assessed the pharmacological activity of triethyl-(beta-4-stilbenoxy-ethyl) ammonium (MG624), a drug that is active on neuronal nicotinic receptors (nicotinic AChR). Experiments on the major nicotinic AChR subtypes present in chick brain, showe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa38f6cfb3d037fbc74e77cf26efa27c
https://pubmed.ncbi.nlm.nih.gov/10051147
https://pubmed.ncbi.nlm.nih.gov/10051147
Autor:
Francesca Grassi, Jean-Marc Matter, Marc Ballivet, Sergio Fucile, Davide Ragozzino, Benedetta Barabino, Stefano Alemà, Linda Erkman, F. Eusebi
Publikováno v:
European Journal of Neuroscience, Vol. 10, No 1 (1998) pp. 172-178
We examine some of the biological and physiological properties of the avian alpha6 neuronal nicotinic acetylcholine receptor (nAChR) subunit. We show here that, beginning at embryonic day 5, alpha6 mRNA is abundantly expressed in the developing chick
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec487d79ad59b1f29c703d93ba5a4c75
https://pubmed.ncbi.nlm.nih.gov/9753124
https://pubmed.ncbi.nlm.nih.gov/9753124
Autor:
Ricardo Miledi, Richard M. Woodward, F. Eusebi, Larry E. Overman, Davide Ragozzino, Y. Murata
Publikováno v:
Molecular Pharmacology. 83:1276-1276
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ad4accd833d381d4f8248a3a4760f3c
https://doi.org/10.1124/mol.113.06er13
https://doi.org/10.1124/mol.113.06er13