Zobrazeno 1 - 10
of 13
pro vyhledávání: '"F. E. Parkinson"'
Autor:
C J, Sinclair, A E, Powell, W, Xiong, C G, LaRivière, S A, Baldwin, C E, Cass, J D, Young, F E, Parkinson
Publikováno v:
British journal of pharmacology. 134(5)
1. Adenosine kinase (AK) inhibitors can enhance adenosine levels and potentiate adenosine receptor activation. As the AK inhibitors 5' iodotubercidin (ITU) and 5-amino-5'-deoxyadenosine (NH(2)dAdo) are nucleoside analogues, we hypothesized that nucle
Publikováno v:
Canadian journal of physiology and pharmacology. 76(12)
Propentofylline is neuroprotective in vivo, but its mechanism of action is not completely understood. Previously, propentofylline was shown to block adenosine transport processes, to inhibit three adenosine receptor subtypes, and to inhibit cAMP phos
Autor:
S L, Borgland, F E, Parkinson
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 281(1)
At least seven functionally distinct nucleoside transport processes exist; however, mouse leukemic L1210/MA27.1 cells possess only one subtype, a Na+-dependent transporter termed N1/cif. The capacity of this transporter subtype to release nucleosides
Autor:
F E, Parkinson, J D, Geiger
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 277(3)
Iodotubercidin is an adenosine kinase inhibitor that through its ability to increase levels of endogenous adenosine can enhance adenosine's receptor-mediated effects. We investigated whether iodotubercidin can inhibit [3H]adenosine accumulation by in
Publikováno v:
Biochemical pharmacology. 46(5)
The neuroprotective effects of adenosine are well-recognized. Recently, propentofylline, a xanthine derivative, has been shown to increase extracellular concentrations of adenosine in ischemic brain and to limit the extent of neuronal damage in exper
Publikováno v:
Drug design and discovery. 9(3-4)
Publikováno v:
Cerebrovascular and brain metabolism reviews. 4(4)
Recent experimental data indicate a probable role of adenosine as an endogenous neuroprotective substance in brain ischemia. This nucleoside is rapidly formed during ischemia as a result of intracellular breakdown of ATP and it is subsequently transp
Autor:
A. S. Clanachan, F. E. Parkinson
Publikováno v:
Purines in Cellular Signaling ISBN: 9781461279969
The passage of adenosine and other nucleosides across plasma membranes may occur by simple diffusion, or may be mediated by nucleoside-specific transport systems that are intrinsic components of the plasma membrane. Both facilitated diffusion and sod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::526f6753b6f3a717a9b97bb7c85cfbab
https://doi.org/10.1007/978-1-4612-3400-5_4
https://doi.org/10.1007/978-1-4612-3400-5_4
Publikováno v:
La Houille Blanche. 72:441-449
Le projet hydroelectrique Andekaleka sur la Riviere Vohitra a Madagascar (chute : 214 m ; 56 MW) a ete mis en service en 1982. L'amenagement comprend une prise d'eau concue pour que les sediments de la riviere ne puissent pas s'introduire dans la gal
Publikováno v:
Journal of Hydraulic Engineering. 113:1019-1031
Tropical rivers often transport a heavy bed load and have a high silt content, and their surface waters carry leaves, twigs, and an occasional tree or branch. Extracting reasonably clean water for a high head power plant usually requires the installa