Zobrazeno 1 - 10
of 33
pro vyhledávání: '"F. E. Cotter"'
Autor:
I. A. Auer, T. C. Greiner, Randy D. Gascoyne, J. M. Conners, Douglas E. Horsman, Warren G. Sanger, F. E. Cotter
Publikováno v:
Annals of Oncology. 8:979-985
Summary Background Low grade malignant lymphomas arising from mucosa associated lymphoid tissue (MALT) represent a distinct clinicopathological entity. The cytogenetic findings and molecular genetics of MALT lymphomas remain minimally defined. Cytoge
Autor:
C F, Pocock, F E, Cotter
Publikováno v:
Methods in molecular medicine. 6
Chromosome rearrangements of chromosome 11 at band 1 1q23 are detected in a high proportion of infant leukemias (l yr) as well as childhood and adult acute leukemlas of both myelold and lymphold types. Molecular and cytogenetic analysis of these tumo
Publikováno v:
British journal of haematology. 112(3)
Bcl-XL, a member of the Bcl-2-related anti-apoptosis protein family, antagonizes a diverse range of apoptosis-inducing stimuli by preventing mitochondrial permeability transition, release of apoptogenic factors including cytochrome C, and caspase act
Autor:
D A, Fennell, F E, Cotter
Publikováno v:
Cytometry. 39(4)
Cytofluorometric analysis allows single-cell resolution of all-or-none programmed cell death (apoptosis) responses and permits direct measurement of cumulative frequency distributions (CFDs) of apoptosis sensitivity from which the median apoptosis to
Autor:
F E, Cotter
Publikováno v:
Seminars in hematology. 36(4 Suppl 6)
Many tumor cells are inherently resistant to curative treatment due to an altered pattern of gene expression. It is an attractive and logical proposition to use this difference within the lymphoma cell to eradicate the malignant process. One such new
Autor:
F I, Raynaud, R M, Orr, P M, Goddard, H A, Lacey, H, Lancashire, I R, Judson, T, Beck, B, Bryan, F E, Cotter
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 281(1)
An 18-mer full-phosphorothioate oligonucleotide with sequence antisense to the first six codons of the open reading frame of bcl-2 (G3139) has shown efficacy against the DoHH2 lymphoma implanted in severe combined immunodeficient mice. This study eva
Autor:
F E, Cotter
Publikováno v:
Hematological oncology. 15(1)
The potential ability of antisense oligonucleotides to downregulate the expression of oncogenes involved in lymphoma, with minimal toxicity can be achieved. The possibility of combining antisense therapy such as BCL-2 antisense with chemotherapy will
Autor:
F E, Cotter
Publikováno v:
Cancer surveys. 30
Autor:
S, Devereux, F E, Cotter
Publikováno v:
Bailliere's clinical haematology. 9(4)
The availability of molecular genetic technology has opened up a large range of potential strategies for the treatment of lymphoma. In the immediate future it is likely that these techniques will be of most use in the evaluation of procedures such as