Zobrazeno 1 - 10
of 847
pro vyhledávání: '"F. Dreyfus"'
Autor:
Yanying Huo, Akshada Sawant, Yongmei Tan, Amar H Mahdi, Tao Li, Hui Ma, Vrushank Bhatt, Run Yan, Jake Coleman, Cheryl F Dreyfus, Jessie Yanxiang Guo, M Maral Mouradian, Eileen White, Bing Xia
Publikováno v:
PLoS Genetics, Vol 18, Iss 4, p e1010138 (2022)
The PALB2 tumor suppressor plays key roles in DNA repair and has been implicated in redox homeostasis. Autophagy maintains mitochondrial quality, mitigates oxidative stress and suppresses neurodegeneration. Here we show that Palb2 deletion in the mou
Externí odkaz:
https://doaj.org/article/a14fbad6b37441618cc40a94f6c51743
Autor:
Hyosung Kim, Ranjie Xu, Ragunathan Padmashri, Anna Dunaevsky, Ying Liu, Cheryl F. Dreyfus, Peng Jiang
Publikováno v:
Stem Cell Reports, Vol 12, Iss 5, Pp 890-905 (2019)
Summary: The process of oligodendrogenesis has been relatively well delineated in the rodent brain. However, it remains unknown whether analogous developmental processes are manifested in the human brain. Here we report oligodendrogenesis in forebrai
Externí odkaz:
https://doaj.org/article/241818fa296d41cf9c4c06f2339510a5
Autor:
Yangyang Huang, Yeri J. Song, Maria Isaac, Shir Miretzky, Ashish Patel, W. Geoffrey McAuliffe, Cheryl F. Dreyfus
Publikováno v:
ASN Neuro, Vol 12 (2020)
The levels of brain-derived neurotrophic factor (BDNF) in the corpus callosum have previously been shown to have a critical impact on oligodendrocyte (OLG) lineage cells during cuprizone-elicited demyelination. In particular, BDNF+/– mice exhibit g
Externí odkaz:
https://doaj.org/article/a0a9ff7635ce4319ae585bba69dba61b
Autor:
Qili Yu, Ryan Hui, Jiyoung Park, Yangyang Huang, Alexander W. Kusnecov, Cheryl F. Dreyfus, Renping Zhou
Publikováno v:
Cell & Bioscience, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Background Multiple sclerosis (MS) is a severe neurological disorder, characterized by demyelination of the central nervous system (CNS), and with a prevalence of greater than 2 million people worldwide. In terms of research in MS pathology,
Externí odkaz:
https://doaj.org/article/81ebbae3e9f446b899be37230a7431e0
Autor:
Ashish Patel, Kyle S. Saitta, Cheryl F. Dreyfus, Lauren D. Lercher, Yangyang Huang, Geoffrey McAuliffe, Danielle M. Sainato
Publikováno v:
Glia
It is well recognized that astrocytes can produce factors known to affect the myelination process. One such factor, brain-derived neurotrophic factor (BDNF), can enhance the differentiation of oligodendrocyte lineage cells following a demyelinating l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b8913c304788da9486a694431f3942c
https://doi.org/10.1002/glia.24003
https://doi.org/10.1002/glia.24003
Autor:
Yanying Huo, Akshada Sawant, Yongmei Tan, Amar H Mahdi, Tao Li, Hui Ma, Vrushank Bhatt, Run Yan, Jake Coleman, Cheryl F Dreyfus, Jessie Yanxiang Guo, M. Maral Mouradian, Eileen White, Bing Xia
Publikováno v:
PLoS genetics. 18(4)
The PALB2 tumor suppressor plays key roles in DNA repair and has been implicated in redox homeostasis. Autophagy maintains mitochondrial quality, mitigates oxidative stress and suppresses neurodegeneration. Here we show that Palb2 deletion in the mou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f401ec0f180df1fe0fa90dddab92d5
https://pubmed.ncbi.nlm.nih.gov/35404932
https://pubmed.ncbi.nlm.nih.gov/35404932
Autor:
M. Maral Mouradian, Jake Coleman, Run Yan, Bing Xia, Tao Li, Vrushank Bhatt, Eileen White, Hui Ma, Cheryl F. Dreyfus, Yanying Huo, Jessie Yanxiang Guo, Amar H. Mahdi, Akshada Sawant, Yongmei Tan
SummaryThe PALB2 tumor suppressor plays key roles in DNA repair and has been implicated in redox homeostasis. Autophagy maintains mitochondrial quality, mitigates oxidative stress and suppresses neurodegeneration. Here we show that Palb2 deletion in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::500822e0665046114f1cdef9f1c1cf4e
https://doi.org/10.1101/2021.06.07.447248
https://doi.org/10.1101/2021.06.07.447248
Publikováno v:
Neurobiology of Disease, Vol 7, Iss 6, Pp 574-585 (2000)
Recent studies suggest that the injured adult spinal cord responds to brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT3) with enhanced neuron survival and axon regeneration. Potential neurotrophin sources and cellular localization in s
Externí odkaz:
https://doaj.org/article/b18aaaddb8a041f88fe3606d37ea6e8a
Publikováno v:
Brain Res
Astrocytes are traditionally recognized for their multiple roles in support of brain function. However, additional changes in these roles are evident in response to brain diseases. In this review, we highlight positive and negative effects of astrocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a7a9d14ae2de9fdec2b4a2391763362
https://pubmed.ncbi.nlm.nih.gov/33812850
https://pubmed.ncbi.nlm.nih.gov/33812850
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