Zobrazeno 1 - 4
of 4
pro vyhledávání: '"F. Craig Stevens"'
Autor:
Hong Yu, Sean P. Hollinshead, Anne B. Need, Akihiko Kato, Daniel Ray Mayhugh, Diseroad Benjamin Alan, Paul L. Ornstein, Jon K. Reel, Patrick Gianpietro Spinazze, Jeff Schkeryantz, David S. Bredt, Oscar de Frutos, Beverly A. Heinz, Kevin Matthew Gardinier, Debra Luffer-Atlas, F. Craig Stevens, Vanessa N. Barth, Warren J. Porter, Timothy Andrew Woods, Douglas Linn Gernert, Gregory A. Stephenson, Jeffrey M. Witkin, Kevin D. Burris, Prashant V. Desai, Patric James Hahn, Scott D. Gleason, Steven Swanson, Chunjin Ding, Albert Khilevich
Publikováno v:
Journal of medicinal chemistry. 59(10)
Transmembrane AMPA receptor regulatory proteins (TARPs) are a family of scaffolding proteins that regulate AMPA receptor trafficking and function. TARP γ-8 is one member of this family and is highly expressed within the hippocampus relative to the c
Autor:
Droste Christine A, Cynthia Darshini Jesudason, Frank C. Tinsley, Aidas Kriauciunas, Anthony G. Borel, F. Craig Stevens, Mark L. Heiman, Marlene L. Cohen, William E. Bloomquist, Daniel Jon Sall
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:6270-6273
The synthesis and biological evaluation of a series of oxindole beta(3) adrenergic receptor agonists is described. A modulation of rat atrial tachycardia was observed with substitution at the 3-position of the oxindole moiety.
Autor:
Heinrich J. Schostarez, F. Craig Stevens, John E. Bleasdale, Theresa J. O’Sullivan, Scott D. Larsen, Charlotta Liljebris, Derek Ogg, Barbara J. Palazuk, Tjeerd Barf, Paul D. May
Publikováno v:
Journal of Medicinal Chemistry. 45:598-622
Protein tyrosine phosphatase 1B (PTP1B) negatively regulates insulin signaling in part by dephosphorylating key tyrosine residues within the regulatory domain of the beta-subunit of the insulin receptor (IR), thereby attenuating receptor tyrosine kin
Autor:
Samuel W. Oldham, M. Joelle Dill, Brian Morgan Watson, Craig W. Lindsley, Don Richard Finley, Dana Sindelar, Lisa Selsam Beavers, Cynthia Darshini Jesudason, Philip Arthur Hipskind, Robert Alan Gadski, Ajay Singh, Christopher Stephen Siedem, Jeffrey W Cramer, R. Todd Pickard, F. Craig Stevens
Publikováno v:
Bioorganicmedicinal chemistry letters. 16(13)
The synthesis and biological evaluation of novel tetrahydroisoquinoline, tetrahydroquinoline, and tetrahydroazepine antagonists of the human and rat H(3) receptors are described. The substitution around these rings as well as the nature of the substi