Zobrazeno 1 - 10
of 532
pro vyhledávání: '"F. Coskun"'
Autor:
Mayar Allam, Thomas Hu, Jeongjin Lee, Jeffrey Aldrich, Sunil S. Badve, Yesim Gökmen-Polar, Manali Bhave, Suresh S. Ramalingam, Frank Schneider, Ahmet F. Coskun
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-21 (2022)
Abstract The Immunoscore is a method to quantify the immune cell infiltration within cancers to predict the disease prognosis. Previous immune profiling approaches relied on limited immune markers to establish patients’ tumor immunity. However, imm
Externí odkaz:
https://doaj.org/article/9e5070068683451ebbd1a83b5eb66b7b
Publikováno v:
IEEE Access, Vol 10, Pp 109814-109849 (2022)
Increasing number of devices connected to the networks, applications and demands of new generation wireless communications cause very high energy consumption resulting in large amount of carbon emission. Thus, energy harvesting solutions together wit
Externí odkaz:
https://doaj.org/article/9e50d54be7cf47d5b33aa24b60031d0b
Autor:
Shuangyi Cai, Thomas Hu, Mythreye Venkatesan, Mayar Allam, Frank Schneider, Suresh S. Ramalingam, Shi-Yong Sun, Ahmet F. Coskun
Publikováno v:
iScience, Vol 25, Iss 9, Pp 104980- (2022)
Summary: Protein-protein interaction networks are altered in multi-gene dysregulations in many disorders. Image-based protein multiplexing sheds light on signaling pathways to dissect cell-to-cell heterogeneity, previously masked by the bulk assays.
Externí odkaz:
https://doaj.org/article/2973f78274a64a138c9d983aadb5dd2c
Autor:
Xavier Rovira-Clavé, Sizun Jiang, Yunhao Bai, Bokai Zhu, Graham Barlow, Salil Bhate, Ahmet F. Coskun, Guojun Han, Chin-Min Kimmy Ho, Chuck Hitzman, Shih-Yu Chen, Felice-Alessio Bava, Garry P. Nolan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Multiplexed ion beam imaging can provide subcellular localisation information but with limited resolution. Here the authors report an ion beam imaging method with nanoscale resolution which they use to assess the subcellular distribution of cisplatin
Externí odkaz:
https://doaj.org/article/18ad42beb0ae47dfab30d767ad938893
Autor:
Mayar Allam, Thomas Hu, Shuangyi Cai, Krishnan Laxminarayanan, Robert B. Hughley, Ahmet F. Coskun
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Allam, Hu, et al. present SpatialViz, a suite of algorithms to explore spatial relationships in multiplexed tissue images by visualizing and quantifying single-cell granularity and anatomical complexity in diverse multiplexed tissue imaging data. The
Externí odkaz:
https://doaj.org/article/58ad3fe1ce344e29a65c37672e679c0a
Autor:
Ahmet F. Coskun, Guojun Han, Shambavi Ganesh, Shih-Yu Chen, Xavier Rovira Clavé, Stefan Harmsen, Sizun Jiang, Christian M. Schürch, Yunhao Bai, Chuck Hitzman, Garry P. Nolan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Secondary ion beam mass spectrometry (SIMS) is a method to obtain a chemical snapshot of biological tissue, but the spatial resolution is low. Here, the authors develop a computational and technology pipeline to localise a chemical signal in SIMS in
Externí odkaz:
https://doaj.org/article/882ce2bc30f347449f3e0769771cb2d7
Autor:
Shivem B. Shah, Christopher R. Carlson, Kristine Lai, Zhe Zhong, Grazia Marsico, Katherine M. Lee, Nicole E. Félix Vélez, Elisabeth B. Abeles, Mayar Allam, Thomas Hu, Lauren D. Walter, Karen E. Martin, Khanjan Gandhi, Scott D. Butler, Rishi Puri, Angela L. McCleary-Wheeler, Wayne Tam, Olivier Elemento, Katsuyoshi Takata, Christian Steidl, David W. Scott, Lorena Fontan, Hideki Ueno, Benjamin D. Cosgrove, Giorgio Inghirami, Andrés J. García, Ahmet F. Coskun, Jean L. Koff, Ari Melnick, Ankur Singh
Publikováno v:
Nature Materials. 22:511-523
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::437c365c91fd56ca70ff4d85310517bf
https://doi.org/10.1038/s41563-023-01495-3
https://doi.org/10.1038/s41563-023-01495-3
Publikováno v:
Open Biology, Vol 10, Iss 12 (2020)
Advances in single-cell biotechnology have increasingly revealed interactions of cells with their surroundings, suggesting a cellular society at the microscale. Similarities between cells and humans across multiple hierarchical levels have quantitati
Externí odkaz:
https://doaj.org/article/690f93551b7d48c8ab8cfe402f0a36d8
Autor:
Mythreye Venkatesan, Nicholas Zhang, Benoit Marteau, Yukina Yajima, Nerea Ortiz De Zarate Garcia, Zhou Fang, Thomas Hu, Shuangyi Cai, Adam Ford, Harrison Olszewski, Andrew Borst, Ahmet F. Coskun
Publikováno v:
Scientific Reports. 13
Organelles play important roles in human health and disease, such as maintaining homeostasis, regulating growth and aging, and generating energy. Organelle diversity in cells not only exists between cell types but also between individual cells. There
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b51083abddd225fa326ef072abae911
https://doi.org/10.1038/s41598-023-32474-y
https://doi.org/10.1038/s41598-023-32474-y
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