Zobrazeno 1 - 10
of 681
pro vyhledávání: '"F. Conway"'
Autor:
Sandra Vergara, Xiaohong Zhou, Ulises Santiago, Mounia Alaoui-El-Azher, James F. Conway, Nicolas Sluis-Cremer, Guillermo Calero
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Reverse transcription of the retroviral RNA genome into DNA is an integral step during HIV-1 replication. Despite a wealth of structural information on reverse transcriptase (RT), we lack insight into the intermediate states of DNA synthesis
Externí odkaz:
https://doaj.org/article/604c55c841a74a928827d4be162f45bf
Autor:
Zhangyi Luo, Yixian Huang, Neelu Batra, Yuang Chen, Haozhe Huang, Yifei Wang, Ziqian Zhang, Shichen Li, Chien-Yu Chen, Zehua Wang, Jingjing Sun, Qiming Jane Wang, Da Yang, Binfeng Lu, James F. Conway, Lu-Yuan Li, Ai-Ming Yu, Song Li
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The multifaceted chemo-immune resistance is the principal barrier to achieving cure in cancer patients. Identifying a target that is critically involved in chemo-immune-resistance represents an attractive strategy to improve cancer treatment
Externí odkaz:
https://doaj.org/article/0b5923e3ea74468d8ddf5b8b03b6f127
Publikováno v:
Case Reports in Surgery, Vol 2012 (2012)
This paper describes the case of a 25-year-old woman with virilisation occurring during pregnancy in the presence of metastatic colorectal cancer. Virilisation during pregnancy is rare. The potential causes include adrenal, foetal, or ovarian patholo
Externí odkaz:
https://doaj.org/article/caad2225c2724e6eb4350c4bca5ec637
This book project was initiated in fall 2013 at the University of Nebraska at Omaha (UNO), Nebraska during a Global Engagement Research and Teaching Workshop between faculty from UNO and the University of Agder (UiA), Norway. The anthology presents a
Autor:
Dapeng Sun, Zhe Sang, Yong Joon Kim, Yufei Xiang, Tomer Cohen, Anna K. Belford, Alexis Huet, James F. Conway, Ji Sun, Derek J. Taylor, Dina Schneidman-Duhovny, Cheng Zhang, Wei Huang, Yi Shi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Highly potent neutralizing nanobodies (Nbs) are of great interest as potential COVID-19 therapeutics. Here, the authors show that potent neutralizing Nbs targeting the receptor binding domain (RBD) of the SARS-CoV-2 spike protein are also effective a
Externí odkaz:
https://doaj.org/article/98aa4a733c5b42fb84aa2005c4550187
Autor:
Jasiel O. Strubbe-Rivera, Jason R. Schrad, Evgeny V. Pavlov, James F. Conway, Kristin N. Parent, Jason N. Bazil
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Mitochondria have a remarkable ability to uptake and store massive amounts of calcium. However, the consequences of massive calcium accumulation remain enigmatic. In the present study, we analyzed a series of time-course experiments to ident
Externí odkaz:
https://doaj.org/article/10be602351054d3e97056f991fc7d5e6
Publikováno v:
Journal of Investigative Surgery, Vol 32, Iss 5, Pp 381-392 (2019)
It has been demonstrated that adipose-derived stromal cells (ASCs) are a regenerative cell population with potential uses for bone and cartilage regeneration. However, the biomarker expression and heterogeneity of the population has not been thorough
Externí odkaz:
https://doaj.org/article/e57f9da285f1499bb1152fa6ddd558a0
Publikováno v:
BMC Health Services Research, Vol 19, Iss 1, Pp 1-17 (2019)
Abstract Background Effective collaboration between speech and language therapists (SLTs) and teachers is essential in meeting the needs of children with developmental language disorders in school, but it is difficult to achieve. Currently, many chil
Externí odkaz:
https://doaj.org/article/010472be9d1a4f89aa38fd29e4eda2b2
Autor:
Aoife Lily Gallagher, Rose Galvin, Katie Robinson, Carol-Anne Murphy, Paul F Conway, Alison Perry
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229599 (2020)
BACKGROUND:Population-based studies provide important data to inform policy and service planning for vulnerable children in society. The aim of this study was to characterise social and educational circumstances and self-concept among a nationally re
Externí odkaz:
https://doaj.org/article/884a8be587dc4fd383eabfaab47aabb3
Autor:
Herman K H Fung, Shelley Grimes, Alexis Huet, Robert L Duda, Maria Chechik, Joseph Gault, Carol V Robinson, Roger W Hendrix, Paul J Jardine, James F Conway, Christoph G Baumann, Alfred A Antson
Publikováno v:
Nucleic Acids Research. 50:8719-8732
Many essential cellular processes rely on substrate rotation or translocation by a multi-subunit, ring-type NTPase. A large number of double-stranded DNA viruses, including tailed bacteriophages and herpes viruses, use a homomeric ring ATPase to proc