Zobrazeno 1 - 10
of 315
pro vyhledávání: '"F. Cavicchioli"'
Autor:
V. Haley, Karen O’Leary, F. Cavicchioli, Peter Schmid, E Komulainen, A Shia, L Denne, Catherine Lenihan
Publikováno v:
Cancer Research. 73:P2-09
Background: Up to 30% of triple-negative breast cancers (TNBC) show expression of the androgen receptor (AR) and may therefore be candidates for AR-targeted therapy. Molecular profiling of TNBC has identified the luminal AR (LAR) subset, which shares
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::613c4e5070f21dbf3cf2a90c2cf725f7
https://doi.org/10.1158/0008-5472.sabcs13-p2-09-05
https://doi.org/10.1158/0008-5472.sabcs13-p2-09-05
Autor:
Francesco Mauri, Marco Merlano, Karen O’Leary, F. Cavicchioli, A Shia, Manfred Wischnewsky, Tim Crook, Peter Schmid, C. Lo Nigro, Alberto Comino, Kimberly Walter, Mark R. Lackner, V. Haley
Publikováno v:
British Journal of Cancer
Background: The transforming growth factor-beta (TGF- β) pathway has been implicated in proliferation, migration and invasion of various cancers. Endoglin is a TGF-β accessory receptor that modulates signalling. We identified Endoglin as an epigene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9fd6ac36bf4ed655a8abbf14ac5ec8d
https://pubmed.ncbi.nlm.nih.gov/26325105
https://pubmed.ncbi.nlm.nih.gov/26325105
Autor:
V. Haley, Peter Schmid, Karen O’Leary, Mark R. Lackner, F. Cavicchioli, Alistair Thompson, A Shia, Tim Crook, Nigro C Lo
Publikováno v:
Cancer Research. 72:P4-06
Background: Methylation-dependent transcriptional silencing of genes involved in amino acid synthesis can provide potential targets for novel synthetic lethality strategies. Glutamine synthetase (Glul) is the key enzyme in the biosynthesis of glutami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b813455d8bd27c98fb67ca160f8c189a
https://doi.org/10.1158/0008-5472.sabcs12-p4-06-10
https://doi.org/10.1158/0008-5472.sabcs12-p4-06-10
Autor:
Catherine Lenihan, A Shia, Ai Nagano, Peter Schmid, Victoria Haley, Karen O’Leary, Natasha Sahgal, Cristiana Lo Nigro, Claude Chelala, F. Cavicchioli, Juliette Chupin
Publikováno v:
Cancer Research. 77:104-104
HER2 is over-expressed in around 20-25% of breast cancers. Due to increased cell growth and differentiation signaling resulting from HER2 over-expression, this sub-type of the disease is associated with aggressive tumor progression and poor prognosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::810d21681cf49e00550b2ea25cdd0db5
https://doi.org/10.1158/1538-7445.am2017-104
https://doi.org/10.1158/1538-7445.am2017-104
Autor:
Dong, Zijun1 (AUTHOR) rivera.lem@gmail.com, Fuentes, Lemuel Rivera1 (AUTHOR) srao1@ualberta.ca, Rao, Sharon1 (AUTHOR) peter.kotanko@rriny.com, Kotanko, Peter1,2 (AUTHOR)
Publikováno v:
Toxins. Aug2024, Vol. 16 Issue 8, p351. 18p.
Autor:
Alberto Comino, C. Lo Nigro, V. Haley, Paola Vanella, Peter Schmid, Manfred Wischnewsky, Karen O’Leary, A Shia, F. Cavicchioli, Tim Crook
Publikováno v:
Annals of Oncology. 23:ix73-ix74
Background The transforming growth factor-beta (TGF-β) pathway is implicated in proliferation, migration, invasion, and metastasis of various cancers. Endoglin, a TGF-β accessory receptor which modulates TGF-β signalling, was identified in a genom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4f34209a56cce0d8e758ccbd14e3b68
https://doi.org/10.1016/s0923-7534(20)32750-2
https://doi.org/10.1016/s0923-7534(20)32750-2
Autor:
N. Syed, Tim Crook, Alistair Thompson, Carlo Palmieri, Peter Schmid, Karen O’Leary, A Shia, F. Cavicchioli, C. Lo Nigro, V. Haley
Publikováno v:
Annals of Oncology. 23:ix532-ix533
Background Loss of argininosuccinate synthetase (ASS1) or lyase (ASL) expression, critical for the biosynthesis of arginine in normal tissues, due to methylation-dependent silencing sensitises ovarian or glioblastoma cells to arginine depletion thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9a0a98ad22760f476ce10cfe3ffcf93
https://doi.org/10.1016/s0923-7534(20)34204-6
https://doi.org/10.1016/s0923-7534(20)34204-6
Autor:
Anaspure, Omkar1 (AUTHOR) omkar.anaspure@pennmedicine.upenn.edu, Patel, Shiv1 (AUTHOR), Baumann, Anthony N.2 (AUTHOR) abaumann@neomed.edu, Anastasio, Albert T.3 (AUTHOR) albert.anastasio@gmail.com, Walley, Kempland C.4 (AUTHOR) kcwalley@med.umich.edu, Kelly, John D.5 (AUTHOR) john.kelly@pennmedicine.upenn.edu, Lau, Brian C.3 (AUTHOR) brian.lau@duke.edu
Publikováno v:
Life (2075-1729). May2024, Vol. 14 Issue 5, p584. 17p.
Publikováno v:
European Journal of Cancer. 48:S132
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2812e434a06acc8b58d4091a6b2981c3
https://doi.org/10.1016/s0959-8049(12)71215-7
https://doi.org/10.1016/s0959-8049(12)71215-7
Autor:
Peter Schmid, Marco Merlano, F. Cavicchioli, Carlo Palmieri, Martino Monteverde, Laura Lattanzio, C. Lo Nigro, Tim Crook, Federica Tonissi, N. Syed, Ornella Garrone, Federico Roncaroli, AM Thompson, Angela McHugh, Alberto Comino
Publikováno v:
Journal of Clinical Oncology. 29:e11553-e11553
e11553 Background: Ecto-5-prime-nucleotidase (NT5E; CD73) catalyzes the conversion of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. Deficiency of NT5 occurs in a variety of immunodeficiency diseases and some studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c6c55d75b2556b1fa0aadf38c8a9300
https://doi.org/10.1200/jco.2011.29.15_suppl.e11553
https://doi.org/10.1200/jco.2011.29.15_suppl.e11553