A redox-dependent thiol-switch and a Ca2+ binding site within the hinge region hierarchically depend on each other in α7β1 integrin regulation

Autor: Michele F. Caliandro, Felix Schmalbein, Luca Matteo Todesca, Matthias Mörgelin, Maryam Rezaei, Juliane Meißner, Isabel Siepe, Julius Grosche, Albrecht Schwab, Johannes A. Eble

Publikováno v: Free Radical Biology and Medicine. 187:38-49

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::823fe51aa97d77681cf8d7febd168397
https://doi.org/10.1016/j.freeradbiomed.2022.05.013

Extracellular Redox Regulation of α7β Integrin-Mediated Cell Migration Is Signaled via a Dominant Thiol-Switch

Autor: Christoph Westerhausen, Michele F. Caliandro, Lukas Bergerhausen, Juliane Meißner, Gereon Poschmann, Julius Grosche, Matthias Mörgelin, Maryam Rezaei, Andrej Kamenac, Dietmar Vestweber, Eva-Maria Hanschmann, Johannes A. Eble, Christina Hecker

Publikováno v: Antioxidants, Vol 9, Iss 3, p 227 (2020)
Antioxidants
Volume 9
Issue 3

While adhering to extracellular matrix (ECM) proteins, such as laminin-111, cells temporarily produce hydrogen peroxide at adhesion sites. To study the redox regulation of &alpha
7&beta
1 integrin-mediated cell adhesion to laminin-111, a co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48c589774506e65537a19ec1f9307247
https://www.mdpi.com/2076-3921/9/3/227

The Interaction between Laminin-332 and α3β1 Integrin Determines Differentiation and Maintenance of CAFs, and Supports Invasion of Pancreatic Duct Adenocarcinoma Cells

Autor: Johannes A. Eble, Augusto Martins Lima, Martin Stehling, Jörg Haier, Cord Brakebusch, Ana C. Martins Cavaco, Sameer A. Dhayat, Michele F. Caliandro, Maryam Rezaei

Publikováno v: Cancers, Vol 11, Iss 1, p 14 (2018)
Cancers
Volume 11
Issue 1
Cavaco, A C M, Rezaei, M, Caliandro, M F, Lima, A M, Stehling, M, Dhayat, S A, Haier, J, Brakebusch, C & Eble, J A 2019, ' The Interaction between Laminin-332 and α3β1 Integrin Determines Differentiation and Maintenance of CAFs, and Supports Invasion of Pancreatic Duct Adenocarcinoma Cells ', Cancers, vol. 11, no. 1, 14, pp. 1-20 . https://doi.org/10.3390/cancers11010014

Ranking among the most lethal tumour entities, pancreatic duct adenocarcinoma cells invade neighbouring tissue resulting in high incidence of metastasis. They are supported by tumour stroma fibroblasts which have undergone differentiation into cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e8b29523d38fd6f6f81adced6506eb5
http://www.mdpi.com/2072-6694/11/1/14

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

992 Nebulised Iloprost and Noninvasive Respiratory Support as a First Treatment for Hypoxaemic Respiratory Failure in Ex-Preterm Infants: Preliminary Experience

Autor: F. Caliandro, Marco Piastra, Laura Marzano, Ersilia Luca, Daniele De Luca, Federico Visconti, Domenico Pietrini, G. De Rosa, G. Conti

Publikováno v: Archives of Disease in Childhood. 97:A284-A284

Objective To describe a series of ex-preterm infants admitted to pediatric intensive care unit because of acute hypoxaemic respiratory failure complicated by pulmonary hypertension who were treated electively combining noninvasive ventilation (NIV) a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::db9646dad945f3df39575e20366e0b54
https://doi.org/10.1136/archdischild-2012-302724.0992