Zobrazeno 1 - 10
of 26
pro vyhledávání: '"F. C. Szoka"'
Autor:
R E, Eliaz, F C, Szoka
Publikováno v:
Cancer research. 61(6)
Certain tumors, including many that are found in the lung, overexpress the CD44 cell-surface marker. CD44 is a receptor that binds to hyaluronan (HA), a carbohydrate consisting of beta1,3 N-acetyl glucosaminyl-beta1,4 glucuronide. We hypothesized tha
Autor:
S. C. Davis, F. C. Szoka
Publikováno v:
ACS Symposium Series ISBN: 9780841235953
Intelligent Materials for Controlled Release
Intelligent Materials for Controlled Release
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b050437468c29d01328d371e85503a80
https://doi.org/10.1021/bk-1999-0728.ch013
https://doi.org/10.1021/bk-1999-0728.ch013
Molecular modeling of the intestinal bile acid carrier: a comparative molecular field analysis study
Publikováno v:
Journal of computer-aided molecular design. 11(6)
A structure-binding activity relationship for the intestinal bile acid transporter has been developed using data from a series of bile acid analogs in a comparative molecular field analysis (CoMFA). The studied compounds consisted of a series of bile
Publikováno v:
Pharmaceutical research. 14(2)
To investigate the ability of the human intestinal bile acid transporter to transport cholic acid conjugates with potential HIV-1 protease inhibitory activity.Cholic acid was conjugated at the 24 position of the sterol nucleus with various amino acid
Intracellular distribution and mechanism of delivery of oligonucleotides mediated by cationic lipids
Autor:
O, Zelphati, F C, Szoka
Publikováno v:
Pharmaceutical research. 13(9)
To study the parameters influencing the intracellular trafficking of oligonucleotides delivered by cationic 1,2-dioleoyl-3-trimethy- lammonium-propane (DOTAP) lipids and to elucidate the mechanism of uptake.We have studied the intracellular localizat
Publikováno v:
Pharmaceutical research. 13(4)
To investigate whether transdermal iontophoresis may be potentially useful for delivery of oligonucleotide drugs, the electrotransport of representative bases (uracil and adenine), nucleosides (uridine and adenosine) and nucleotides (AMP, ATP, GTP an
Publikováno v:
Gene therapy. 3(3)
The expression of naked plasmid DNA coding for firefly luciferase (pRSVluc) or a secreted protein, human-alpha-1-antitrypsin (pRcCMVhAAT) in mouse skeletal muscle was characterized following administration by an improved intramuscular injection techn
Publikováno v:
Gene therapy. 2(7)
Intratracheal administration of plasmid DNA resulted in gene expression in mouse airways in the absence of any enhancing agent. Administration of plasmid DNA encoding the chloramphenicol acetyltransferase gene (CAT) in sterile water lead to CAT trans
Autor:
R A, Stull, F C, Szoka
Publikováno v:
Pharmaceutical research. 12(4)
Nucleic acids are increasingly being considered for therapeutic uses, either to interfere with the function of specific nucleic acids or to bind specific proteins. Three types of nucleic acid drugs are discussed in this review: aptamers, compounds wh
Autor:
J Y, Legendre, F C, Szoka
Publikováno v:
Pharmaceutical research. 9(10)
We compare the transfection efficiency of plasmid DNA encoding either luciferase or beta-galactosidase encapsulated in pH-sensitive liposomes or non-pH-sensitive liposomes or DNA complexed with cationic liposomes composed of dioleoyloxypropyl-trimeth