Zobrazeno 1 - 10
of 13
pro vyhledávání: '"F. C. Oback"'
Autor:
Björn Oback, F. C. Oback, Kathrin Stamms, Jingwei Wei, Pavla Turner, Andria Green, Romina Bennewitz, Fanli Meng
Publikováno v:
Biology of Reproduction. 103:114-125
Correct reprogramming of epigenetic marks in the donor nucleus is a prerequisite for successful cloning by somatic cell transfer (SCT). In several mammalian species, repressive histone (H) lysine (K) trimethylation (me3) marks, in particular H3K9me3,
Autor:
Pavla Turner, Kathrin Stamms, Björn Oback, F. C. Oback, Jingwei Wei, Romina Bennewitz, Andria Green, Fanli Meng
Correct reprogramming of epigenetic marks in the donor nuclei is a prerequisite for successful cloning by somatic cell transfer. In several mammalian species, repressive histone (H) lysine (K) trimethylation (me3) marks, in particular H3K9me3, form a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::653742d6e4f641ae06baafb2cd2dcaae
https://doi.org/10.1101/699181
https://doi.org/10.1101/699181
Publikováno v:
Molecular and Cellular Biology. 33:974-983
Correct reprogramming of epigenetic marks in the donor nuclei is crucial for successful cloning by nuclear transfer. Specific epigenetic modifications, such as repressive histone lysine methylation marks, are known to be very stable and difficult to
Autor:
Björn Oback, F. C. Oback, Kamran Ghaedi, Götz Laible, Mohsen Forouzanfar, Sayed Morteza Hosseini, Mehdi Hajian, Mohammad Hossein Nasr-Esfahani, Shahin Eghbalsaied
Publikováno v:
REPRODUCTION. 145:97-108
Transgenic mammals have been produced using sperm as vectors for exogenous DNA (sperm-mediated gene transfer (SMGT)) in combination with artificial insemination. Our study evaluated whether SMGT could also be achieved in combination with IVF to effic
Publikováno v:
Biology of Reproduction. 76:268-278
Our objectives were to compare the cellular and molecular effects of aggregating bovine embryonic vs. somatic cell nuclear transfer (ECNT vs. SCNT) embryos and to determine whether aggregation can improve cattle cloning efficiency. We reconstructed c
Autor:
Jingwei Wei, F. C. Oback, L. Popovic, David N. Wells, J. E. Oliver, S. R. Delaney, L. T. McGowan
Publikováno v:
Reproduction, Fertility and Development. 29:154
Dairy cattle breeding schemes increasingly integrate embryo-based genomic selection to accelerate genetic gain. In contrast to the single offspring produced with conventional animal-based genomic selection, multifactorial IVF between elite parents in
Autor:
Pavla Turner, Prasanna Kallingappa, Alice M. Chibnall, Michael P. Eichenlaub, David N. Wells, Björn Oback, F. C. Oback, Andria Green
Publikováno v:
Biology of Reproduction. 95:16-16
Reprogramming by nuclear transfer (NT) cloning forces cells to lose their lineage-specific epigenetic marks and reacquire totipotency. This process often produces molecular anomalies that compromise clone development. We hypothesized that quiescence
Autor:
J. E. Oliver, L. Popovic, Andria Green, L. T. McGowan, D. Carson, David N. Wells, D. L. Hyndman, F. C. Oback, S. J. Appleby, Fanli Meng
Publikováno v:
Reproduction, Fertility and Development. 28:144
Interspecies somatic cell NT (SCNT) can be used in the conservation of endangered animals but only when there is an abundant source of compatible oocytes and recipients. The objective of this study was to compare the efficiency of intra- and interspe
Autor:
F. C. Oback, David N. Wells
Publikováno v:
Reproduction, Fertility and Development. 25:221
Each in vitro produced bovine embryo has only a limited chance of developing into a live calf. As genetically superior embryos can now be identified (Humblot et al. 2010 Vet. Med. Int.), maximizing these odds is desirable. We aim to multiply the elit
Autor:
Brigid Brophy, Sally-Ann Cole, F. C. Oback, William G. Gavin, S. R. Delaney, J. E. Oliver, M. C. Berg, A. A. Cullum, Götz Laible, D. P. Pollock, H. M. Meade, David N. Wells, M. J. Wright
Publikováno v:
Reproduction, Fertility and Development. 25:315
Dairy animals provide an attractive production platform for biosimilar antibodies due to the high protein production capacity of the mammary gland and easy access to milk. Goats are well suited for this approach as they offer a relatively short gesta