Zobrazeno 1 - 10
of 25
pro vyhledávání: '"F. C. Lucibello"'
Autor:
F. C. Lucibello, Karin U Jooss, Andreas Sewing, Jörk Zwicker, Moira Behn, Sabine Brüsselbach, Rolf Müller
Publikováno v:
Oncogene. 18:19-25
Although cyclin D1 plays a major role during cell cycle progression and is involved in human tumourigenesis, its domain structure is still poorly understood. In the present study, we have generated a series of cyclin D1 N- and C-terminal deletion con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58cd35287806939a9ec72615843d3830
https://doi.org/10.1038/sj.onc.1202286
https://doi.org/10.1038/sj.onc.1202286
Publikováno v:
Oncogene. 16:2957-2963
Cell cycle regulation of the cyclin A gene is determined by a bipartite repressor binding site in the region of the basal promoter, termed CDE-CHR, which also controls the expression of cell cycle genes upregulated in S or G2 (such as cdc25C). The CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac464680140341090367da085a5e11cc
https://doi.org/10.1038/sj.onc.1201838
https://doi.org/10.1038/sj.onc.1201838
Autor:
F. C. Lucibello, Lawrence A. Wolfraim, Ningshu Liu, Rolf Müller, Jörk Zwicker, Kathrin Körner
Publikováno v:
Nucleic Acids Research. 25:4915-4920
The cdc25C , cdc2 and cyclin A promoters are controlled by transcriptional repression through two contiguous protein binding sites, termed the CDE and CHR. In the present study we have identified a factor, CDF-1, which interacts with the cdc25C CDE-C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a7869d7fb4be837c313b94e6d894993
https://doi.org/10.1093/nar/25.24.4915
https://doi.org/10.1093/nar/25.24.4915
Publikováno v:
Nucleic Acids Research. 24:2905-2910
B-myb belongs to a group of cell cycle genes whose transcription is repressed in G0/early G1 through a binding site for the transcription factor E2F. Here, we show that the B-myb repressor element is specifically recognised by heterodimers consisting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::382f50b880991582c37bd7db46c8bcf5
https://doi.org/10.1093/nar/24.15.2905
https://doi.org/10.1093/nar/24.15.2905
Publikováno v:
Nucleic Acids Research. 23:3822-3830
The late S/G2-specific transcription of the human cdc25C gene is dependent on an initiator-proximal repressor element (CDE) and an upstream activating sequence (UAS) of undefined nature. We now show that these upstream sequences harbour multiple in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af411c715912afb30925bd553e76bbc2
https://doi.org/10.1093/nar/23.19.3822
https://doi.org/10.1093/nar/23.19.3822
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. 1155:151-179
II. G1 restriction points in yeast: models for eukaryotic cell-cycle-control mechanisms . . . . . . . . . . . . 152 A. The G1 restriction point (START) in the budding yeast S. cerevisiae . . . . . . . . . . . . . . . . . . . . 153 1. The Cdc28 serine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c1e630a4f65784c7e69e5910f26cc07
https://doi.org/10.1016/0304-419x(93)90003-u
https://doi.org/10.1016/0304-419x(93)90003-u
Publikováno v:
Europe PubMed Central
The state of cellular senescence is characterised by an irreversible arrest in the G1 phase of the cell cycle. It has previously been shown that three cell cycle genes, cyclin A, cyclin B and cdc2, are not expressed in senescent human fibroblasts. Al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80000377f4e12ea11d03e756f51e67ed
https://doi.org/10.1242/jcs.105.1.123
https://doi.org/10.1242/jcs.105.1.123
Publikováno v:
Genes & Development. 5:1212-1223
We show that serum-stimulated fibroblasts transiently express two different forms of fosB mRNA, which are generated by alternative splicing of the transcript from a single gene. In addition to the known long form (fosB-L), encoding a protein of 338 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f70e74c7fd9bc4f7e9d56e6c040a1629
https://doi.org/10.1101/gad.5.7.1212
https://doi.org/10.1101/gad.5.7.1212
Publikováno v:
Nucleic Acids Research. 19:3583-3591
Although the induction of the mouse c-fos promoter by growth factors and specific signal transduction pathways has been analyzed in some detail, the mechanisms involved in the control of basal level transcription remain largely elusive. In this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dc8c6bde050487b922f1fb60cddba54
https://doi.org/10.1093/nar/19.13.3583
https://doi.org/10.1093/nar/19.13.3583
Publikováno v:
Science. 271:1595-1597
DNA-binding E2F complexes have been identified throughout the mammalian cell cycle, including the transcriptionally inactive complexes with pocket proteins, which occur early in the prereplicative G1 phase of the cycle, and the transactivating free E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9692fcecd4c72d59abf50d023de2e979
https://doi.org/10.1126/science.271.5255.1595
https://doi.org/10.1126/science.271.5255.1595